Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07349095Recruiting
AI-assisted color test for gum redness around dental implants
This trial uses an AI tool to check for redness (erythema) in the gum tissue around dental implants. It aims to make diagnosis faster and more accurate during regular check-ups.
ShanghaiAges 18 years+ - NCT07344025Recruiting
Comparing two bone graft materials for tooth socket preservation
This trial tests two different bone graft materials used to preserve the jawbone after a tooth extraction. The goal is to see which material works better to maintain bone for future dental implants.
AlexandriaAges 21–50 - NCT07350343Enrolling by invitation
Comparing 3D-printed vs thermofit clear aligners
This study compares two ways of making clear plastic aligners to straighten teeth. It looks at whether directly 3D-printed aligners work better than ones made by pressing a plastic sheet over a 3D model. This could be for people with mild to moderate teeth alignment issues.
KarbalaAges 16–40 - NCT07351812Recruiting
Two treatments for jaw muscle pain
This study compares two different treatments for people who have pain in their jaw muscles (not the joint itself). It aims to find which treatment works better for muscle-related temporomandibular disorders (TMD).
AlexandriaAges 18–45 - NCT07344038Recruiting
Bioceramic Putty vs MTA and Crowns for Baby Teeth
This study compares two types of putty used to treat the nerve of a deep cavity in a baby tooth, and then looks at two types of crowns (caps) placed on top. It's for healthy children ages 5–7 who need this treatment on a back baby tooth.
AlexandriaAges 5–7 - NCT07345351Enrolling by invitation
Pilates vs. lifestyle advice for jaw muscle pain
This study compares two non-drug treatments for jaw muscle pain: clinical Pilates vs. lifestyle counseling. It aims to see which approach better reduces pain and improves jaw function in women.
Antakya, HatayAges 18–45 - NCT06278194Recruiting
Masseter muscle thickness in gasser ganglion radiofrequency treatment
This trial studies how radiofrequency treatment for facial pain affects the thickness of your chewing muscle. It may help improve future treatments.
Istanbul, BaşakşehirAges 40–85 - NCT07337109Recruiting
Study on tooth sensitivity and quality of life
This study looks at how tooth sensitivity affects your daily life and what treatments people use. It is for people who have recently started having sensitive teeth and have tried products for it.
Las Vegas, NevadaAges 18 years+ - NCT07343050Recruiting
Testing flowable composites for tooth fillings and sensitivity
This trial is testing if a special type of dental filling material (flowable composite) causes less tooth sensitivity after getting a cavity filled. It may help people with cavities in the back teeth.
Merkez, Rize ProvinceAges 18 years+ - NCT07339774RecruitingPhase 2
Traditional Chinese medicine for mouth sores from radiation
This trial tests whether a traditional Chinese medicine can help prevent or reduce the severity of mouth sores caused by radiation therapy for head and neck cancer. If you are scheduled to get radiation for non-spreading head or neck cancer, this treatment might help protect your mouth.
Chengdu, SichuanAges 18–65 - NCT07337057Recruiting
Standardized dental implant outcomes
This study is creating a standard way to measure the success of dental implants. It is for people who need a new implant or a replacement implant, and who do not have major health or mouth problems that would complicate the procedure.
Rotterdam, South HollandAges 18–75 - NCT07340242Recruiting
3D-Printed Braces vs. MARA for jaw alignment
This trial compares two types of braces (a 3D-printed removable brace and a fixed brace called MARA) to see which works better for correcting a bite problem where the lower jaw is too far back. It is designed for teenagers who are still growing and have a large overbite.
Al Mansurah, Dakahlia GovernorateAges 9–14 - NCT07336082Recruiting
Sensory training vs. exercise for awake teeth clenching
This study compares two non-drug treatments—sensory training and exercise therapy—to help people who clench or grind their teeth while awake. It aims to reduce jaw pain and improve daytime function.
AydinAges 18–45 - NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery
This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.
LjubljanaAges 6 months–3 years - NCT07343063Recruiting
Comparing tooth-colored fillings for front teeth cavities
This trial tests different tooth-colored materials for fixing cavities on the front teeth (Class III and IV restorations). It aims to find which type lasts longest and works best for patients in good general health.
Merkez, Rize ProvinceAges 18 years+ - NCT07340515RecruitingPhase 3
Proton vs standard radiation for advanced nasopharyngeal cancer
This trial is testing whether a newer, more precise type of radiation (proton therapy) works better than standard radiation (IMRT) for people with advanced nasopharyngeal cancer. It also includes chemotherapy and immunotherapy to see if the combination can improve outcomes.
Jinan, ShandongAges 18–70 - NCT07340606Recruiting
AI predictions for root canal success in painful molars
This study tests whether an AI tool can help predict if a simpler root canal treatment (pulpotomy) will work for back teeth with adult, painful pulp infections. If successful, it may help avoid more complex procedures.
CairoAges 20–45 - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT06699199RecruitingPhase 4
Testing silver diamine fluoride on mouth bacteria in kids
This study tests if a liquid medicine (silver diamine fluoride) painted on baby teeth cavities can change the bacteria in a child's mouth. It is for healthy children ages 4–10 with an open cavity.
Jeddah, Mecca RegionAges 4–12 - NCT06853639Recruiting
Oral health study for USP students
This trial looks at the oral health of current and former students at the University of São Paulo. It may help understand how to better support dental care in this group.
São PauloAges 18–60 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT05938166Recruiting
Training foreign caregivers with an augmented reality system
This study tests whether an augmented reality (AR) training system can help foreign care workers learn how to provide care. It involves Indonesian caregivers training for caring for older adults in Kaohsiung, with tests based on the older adult’s ability to follow instructions.
Kaohsiung City, Sanmin DistAges 21–65 - NCT06745232Recruiting
New 3D camera system for full mouth dental impressions
This trial tests a new 3D camera system to capture impressions for dental implants. It may help you if you need full mouth implants and have good bone and gum health.
Roma, RMAges Any age - NCT07324928Enrolling by invitation
Pulpotomy treatment for baby teeth using iron sulfate or MTA
This study compares two materials (iron sulfate and a special cement called MTA) used during a pulpotomy—a procedure to treat cavities in baby molars when the nerve is exposed. It aims to find which material works better to keep the tooth healthy until it falls out naturally.
Jizan, Jazan RegionAges 6–10
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.