Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT05337631Recruiting
Care patterns for older people receiving head and neck radiation
This study looks at special ways of providing care for people age 65 and older with certain head-and-neck cancers when they receive radiation (with or without chemotherapy). It aims to understand how care should be organized to better support older patients during treatment.
Baltimore, MarylandAges 65 years+ - NCT06671106Recruiting
Mouthrinse for Teens with Early Gum Disease
This trial tests a special mouthrinse containing amine and zinc lactate to treat plaque-induced gingivitis (gum inflammation caused by plaque) in teenagers. If you or your teen have early gum disease and are eligible for free dental care through the Regional Health Service, this study may offer a home-based treatment option.
FerraraAges 12–14 - NCT06819033RecruitingPhase 4
Light therapy for canker sores in children
This study tests whether a special light treatment (photobiomodulation) can help reduce pain from canker sores (aphthous ulcers) in children. It may be a good option for kids who get painful mouth sores during dental visits.
Houston, TexasAges 5–17 - NCT06893614Recruiting
Facial mesh study for jaw surgery patients
This trial uses computer scans to create facial shape meshes for patients who had jaw surgery to correct an underbite. It aims to improve planning for future surgeries.
Cairo, AbbassiaAges 18–50 - NCT06895395Recruiting
Speech therapy for kids with cleft palate
This study compares different types of speech therapy for children born with a cleft palate who have developed certain speech errors. The goal is to learn which therapy works best from the perspective of the child, their family, and the speech therapist.
GhentAges 4–12 - NCT06755034Recruiting
Single implant to hold lower denture on preferred chewing side
This study tests whether a single dental implant placed in the canine area of your preferred chewing side can better stabilize your lower denture. It may be an option if you are at least 60 years old, have full upper and lower dentures that fit well or can be adjusted, and have healthy jawbone in the front area.
Geneva, Canton of GenevaAges 60 years+ - NCT06819995Recruiting
3D-printed vs milled guides for dental implants
This study compares two types of surgical guides used to place dental implants: one made with a 3D printer and one milled from a solid block. If you're missing one to four teeth and have healthy healed gums and bone, this trial may help determine which guide works best.
MadridAges 21 years+ - NCT07260344Recruiting
Testing two new ways to find early mouth precancer
This study compares two non-invasive methods to detect precancerous sores in the mouth. It aims to find a simpler way to catch early changes before they become cancer.
Taipei, TaipeiAges 30–80 - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT07261735Recruiting
Custom attachments for clear aligner therapy
This study tests whether custom-made attachment composites improve the effectiveness of clear aligners for treating mild-to-moderate crowding or spacing. It may help you achieve better tooth movement during orthodontic treatment.
Ankara, AnkaraAges Any age - NCT07264842RecruitingPhase 2
Comparing two pastes for infected baby molars in children
This trial tests whether a special antibiotic paste or a medicine called simvastatin works better to treat infected baby molars in children. It aims to save the tooth and heal the infection without pulling it.
Karachi, SindhAges 5–8 - NCT07264218Enrolling by invitation
Helping burn survivors with a tight mouth using a custom 3D-printed brace
This study tests a custom-made mouth brace created from a 3D scan of your mouth. The brace may help stretch and improve the opening of a tight mouth caused by burn scars, making daily activities like eating and speaking easier.
SeoulAges 18 years+ - NCT07264127Recruiting
I-arch system for early orthodontic treatment
This study tests a new orthodontic tool, the I-arch system, for straightening the lower front teeth when they are moderately crowded. It aims to see how well the I-arch works during the first stage of braces treatment.
KarbalaAges 12 years+ - NCT07264036Recruiting
Nasal Speech After Head and Neck Cancer Treatment Study
This study is for people who have had treatment for head or neck cancer and now have a nasal-sounding voice. It tests a procedure to help improve speech by adding a small amount of filler material to the back of the throat.
Charlottesville, VirginiaAges 18 years+ - NCT07264491Recruiting
Testing ceramic crowns for front teeth
This study tests how well a new type of ceramic crown (one-piece, tooth-colored) works for teeth in the front of your mouth. It aims to see if these crowns are a good option for people who need a strong, natural-looking replacement.
Cairo, ManialAges 21 years+ - NCT07265830RecruitingPhase 3
School-based program to prevent tooth decay in kids
This trial tests a program in schools to help prevent cavities (tooth decay) in children ages 5 to 13. The goal is to see if school-based care makes it easier for kids to get treatment and keep their teeth healthy.
Glenwood Springs, ColoradoAges 5–13 - NCT07262086Enrolling by invitation
Bioactive filling for deep cavities in back teeth
This trial tests a new type of self-hardening tooth-colored filling material that may help repair and protect deep cavities in back teeth. It is looking for people with two molars that need deep fillings, to see if the material stays strong and helpful over time.
Ismailia, IsmaliaAges 21–45 - NCT07266701Enrolling by invitation
Bite Force Test for Better Treatment Plans
This trial studies a simple bite force test to help doctors assess risks and create personalized treatment plans. It is for adults who can understand Swedish.
Malmö, Skåne CountyAges 18 years+ - NCT07262892Recruiting
3D study of jaw widening methods in children
This trial uses 3D imaging to compare two ways of widening the upper jaw in children. It may help your child if they need jaw expansion and haven't had it before.
Istanbul, FatihAges 6–12 - NCT06068270Recruiting
MOPs cleaning aid for gum disease patients getting braces
This trial tests whether a special type of oral hygiene device (called MOPs) helps protect teeth and gums during orthodontic treatment (braces or aligners) in people with severe gum disease (stage IV periodontitis). It may help prevent further damage and improve the success of moving teeth.
Madrid, MadridAges 18–80 - NCT06711744Recruiting
Comparing dental implants after tooth extraction
This study compares different types of dental implants placed right after a tooth is removed. It may help people with a failing tooth who have healthy gums and surrounding teeth.
Rome, RMAges 18–99 - NCT06320665Recruiting
3D study of wisdom teeth and jaw growth
This study uses a 3D dental x-ray (CBCT) to look at how wisdom teeth that are stuck (impacted) relate to the growth pattern of your jaw. It might help doctors understand why some wisdom teeth get stuck.
NancyAges 15 years+ - NCT06428149Recruiting
Comparing gum surgery techniques for deep pockets
This study looks at three different ways to make cuts in the gums during surgery for deep pockets caused by gum disease. It aims to find which technique helps heal better and save more bone.
Murcia, MurciaAges 18–80 - NCT05592314Recruiting
How dental implant shape affects gum and bone disease rates
This study looks at whether the way a dental implant is restored (the “prosthetic emergence profile,” or how it comes up through the gum) affects how often gum and tissue problems happen around implants. It may help clinicians choose restoration styles that lower the risk of peri-implant diseases.
Sant Cugat del Vallès, BarcelonaAges 18–80
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.