Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT06753669Recruiting
Mothers' action project for child health
This study looks at how to help mothers from South Asian communities support their child's health and development. You and your child would join a program that provides guidance and resources over 12 months.
New York, New YorkAges 1–45 - NCT06755372Recruiting
TLR-4 in gum disease patients with kidney failure
This study looks at a specific immune marker (TLR-4) in people with gum disease, comparing those who also have end-stage kidney disease (on dialysis) to those who are otherwise healthy. The goal is to understand how gum disease might be different when kidney failure is also present.
Al Fayyum, Faiyum GovernorateAges 30–60 - NCT06760884Recruiting
Pregnancy and jaw function study
This study looks at jaw joint function, oral habits, and pain in pregnant and non-pregnant women. It aims to understand how pregnancy might affect these issues.
TrabzonAges 18–45 - NCT06763419Recruiting
Light therapy for jaw joint pain
This trial tests if a non-invasive light therapy (photobiomodulation) can reduce pain and clicking in the jaw joint. It may help people with jaw pain caused by muscle tension or joint issues.
AlexandriaAges 20–40 - NCT06766253Recruiting
Comparing three breathing tube devices for head-down laparoscopic surgery
This study is comparing three different breathing tube devices (GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask) for people having laparoscopic surgery while tilted head-down. The goal is to see which device works best and most safely.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06767670Recruiting
Oral hygiene and germs in kids' mouths with two types of crowns
This study looks at how different types of ready-made crowns for baby molars affect the number of germs in a child's mouth and how oral hygiene plays a role. It might help dentists choose the best crown for kids.
Cairo, Nasr CityAges 4–8 - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT06772051Recruiting
Testing a shorter etching time for cavities
This study is testing if a shorter acid etching time works just as well for filling cavities in children's or adults' back teeth. It may help make the filling process quicker and more comfortable.
Al Mansurah, DakahliyaAges 35–50 - NCT06776653Recruiting
Snoezelen for anxiety during dental care
This trial tests whether adding a calming Snoezelen element to dental care reduces anxiety. It is for adults who can share their feelings during treatment.
Nantes, NantesAges 18 years+ - NCT06776471Recruiting
Sealant study for children with weak enamel
This study compares two types of dental sealants applied to the first permanent molars of children aged 6-12 who have a condition called molar incisor hypomineralization (MIH), which means their back teeth have soft or chalky spots. The goal is to see which sealant works better at protecting these teeth from cavities.
AnkaraAges 6–12 - NCT06778473Recruiting
Acupuncture plus self-rehab for severe Bell's palsy
This study tests whether combining a gentle type of acupuncture (intradermal acupuncture) with a self-guided rehabilitation program can help people with severe Bell's palsy recover better. It is for adults having their first episode of Bell's palsy with significant facial weakness.
Suzhou, JiangsuAges 18 years+ - NCT06778590Recruiting
Comparing two ways to remove lower wisdom teeth
This study compares two methods for removing lower wisdom teeth before they are fully grown. It uses a special ultrasound tool (piezoelectric) versus traditional surgical tools to see which is gentler and leads to faster healing.
CatanzaroAges 14–24 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT06780462RecruitingPhase 3
Steroids with or without blood thinners for Behçet's vein clots
This trial tests whether adding a blood thinner (anticoagulant) to steroid therapy is more effective than steroids alone for treating deep vein thrombosis (a blood clot in a large vein) in people with Behçet's syndrome. It aims to find the best way to prevent future clots and reduce side effects.
BordeauxAges 18 years+ - NCT06782035Recruiting
Effect of dressings on donor site comfort after gum graft surgery
This trial tests whether special dressings applied to the area where a gum graft is taken from can improve patient comfort and quality of life after surgery.
IzmirAges 18–85 - NCT06782191Recruiting
Arthroscopic treatments for jaw joint disc displacement
This trial tests two types of jaw joint surgery for people with a displaced disc that still moves. It compares a simpler procedure (flushing the joint) with a more involved one (surgical repair) to see which helps more with pain and jaw function.
HuddingeAges 18 years+ - NCT06782178Recruiting
Comparing two jaw joint procedures for limited mouth opening
This study compares two minimally invasive procedures (arthroscopy using a tiny camera vs. arthrocentesis using a needle to flush the joint) to see which works better for people with a displaced jaw disc that limits mouth opening. It might help you if simple treatments haven't worked.
HuddingeAges 18 years+ - NCT06783595Recruiting
Gum changes after removing temporary implant crown
This study looks at how the gums around a dental implant change after the temporary crown is removed, in the front upper teeth area. It helps dentists understand healing and gum shape to improve future implant treatments.
Loma Linda, CaliforniaAges 18 years+ - NCT06784817Recruiting
Gum health in smokers and heated tobacco users
This study compares gum health in three groups: daily cigarette smokers, exclusive users of heated tobacco products (like IQOS), and never-smokers. It aims to see if heated tobacco has different effects on gums compared to traditional smoking.
Budapest, Pest CountyAges 18 years+ - NCT06785051Recruiting
AI physiotherapy for oral cancer patients
This study tests an AI-based physiotherapy program for people with newly diagnosed oral cancer. It aims to help patients maintain or improve their movement during cancer treatment, such as surgery, chemotherapy, or radiation.
TaipeiAges 20–65 - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06796270Recruiting
Short-course radiation for nasopharyngeal cancer
This trial tests a shorter course of radiation therapy for people with nasopharyngeal cancer, a type of head and neck cancer. The goal is to see if a hypofractionated (fewer, larger doses) approach is safe and effective.
Haikou, HainanAges 18–75
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.