Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06975358Recruiting
Faster braces with gum surgery and growth factor injections
This study tests if a small gum surgery (alveolar decortication) plus a natural growth factor injection (CGF) can speed up tooth movement in people who need braces and have two teeth removed. It may help you have a shorter treatment time.
Tanta, TantaAges 16–22 - NCT06980714Enrolling by invitation
Electric vs. manual toothbrush for advanced gum disease
This study compares electric and manual toothbrushes to see which one works better for people with advanced gum disease (stage 3 or 4 periodontitis). It might help you find a more effective way to care for your teeth and gums at home.
L’AquilaAges 18 years+ - NCT06974591Recruiting
How your teeth affect your balance
This study looks at how small disturbances to your posture affect your jaw and balance. It compares people with all their natural teeth to those who wear full dentures, to see if the type of teeth you have changes how your body responds.
Boston, MassachusettsAges 30–65 - NCT06967649Enrolling by invitation
Dental implant healing and success over 5 years
This study will check how well dental implants heal and stay healthy over 5 years. It uses implants made by SIN Implant System. The goal is to see if the implant bonds well with your bone and if the gums around it stay healthy.
Niterói, Rio de JaneiroAges 18 years+ - NCT06967402Recruiting
Mouthwash study for gum disease treatment
This study tests two types of mouthwash to see which helps treat gum disease better when used with regular dental care. It may be a good option if you have moderate to severe gum disease and are generally healthy.
Hong KongAges 18 years+ - NCT06967896Recruiting
Comparing breathing tube types for women having thyroid surgery
This trial is testing different types of breathing tubes used during thyroid surgery in women. It aims to find which tube works best to keep the airway safe and reduce side effects.
Anqing, AnhuiAges 18–65 - NCT06968780Recruiting
Comparing two gum grafts for dental implants in the upper jaw
This trial compares two surgical techniques using tissue from the cheek or the roof of the mouth to improve gum health around special implants placed in the cheekbone. It may be an option if you have severe bone loss in your upper jaw and need implants but don't have enough bone for standard ones.
Cairo, Giza GovernorateAges 18 years+ - NCT04340024Recruiting
Testing blood markers linked to how well radiation works
This study looks for “biomarkers,” or measurable signs (often from blood or samples), that may show which cancers respond better to radiation therapy. It may help doctors choose radiation treatment more precisely, especially for people who had significant side effects before.
SingaporeAges 21–99 - NCT05051072Recruiting
MRI study in adults with trigeminal neuralgia pain
This study uses a special MRI scan to look at how the trigeminal nerve system is working in people with essential trigeminal neuralgia (face pain) and whether there is nerve involvement. You may be asked to get MRI scans while resting, which can help doctors better understand the cause and guide future treatments.
ParisAges 18 years+ - NCT06958445Enrolling by invitationPhase 2
Preventing mouth sores during breast cancer radiation
This trial tests whether a natural alginate treatment can reduce painful mouth sores and improve quality of life for women with breast cancer who are receiving radiation after surgery. If you are getting radiation to the breast area and have lymph node involvement, this treatment may help you feel better during therapy.
TaipeiAges 18 years+ - NCT06960460Recruiting
ZygoFix dental implant study for people with severe bone loss
This study tests a new type of zygomatic (cheekbone) dental implant for people who have lost many teeth and have severe bone loss in the upper jaw. The goal is to see how well the implant works and if it stays safe over time.
Toulouse, FranceAges 18 years+ - NCT06955429Recruiting
Testing Biodentine XP for tooth fillings and root treatments
This study tests how well Biodentine XP works over time for fixing cavities or treating tooth roots in children and adults. It aims to see if this material is safe and lasts long in both baby teeth and permanent teeth.
KraainemAges 2 years+ - NCT06511830Recruiting
Comparing plaque detection methods for better dental care
This study compares different ways of checking dental plaque (the sticky film on teeth) to see which method works best. It may help you understand how to better care for your teeth and gums.
Lincoln, NebraskaAges 19–85 - NCT06961045Enrolling by invitation
Nerve repositioning study for dental implants in lower jaw
This study tests a computer-guided technique to move a nerve in the lower jaw so that dental implants can be placed in areas with thin bone. It looks at whether this procedure causes any numbness afterward.
Tanta, Gharbia GovernorateAges 30–75 - NCT06959602Enrolling by invitation
Comparing two root canal cleaning methods for infected teeth
This trial compares two ways of cleaning infected root canals during a root canal procedure. The goal is to see which method better removes bacteria and improves healing.
AthensAges 18–80 - NCT06960070Recruiting
Comparing different types of resin fillings for root‑canal‑treated molars
This study compares two types of resin onlays (custom‑made fillings) to see which works better for molars that have had a root canal. If you have a back tooth with a root canal and a cavity on the top and one side, this trial may help decide the best repair.
Mersin, MersinAges 18–84 - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years - NCT06957509Recruiting
Saliva test to predict cavities in 3-year-olds
This study looks at proteins in the spit of 3-year-old children to see if they can help doctors better predict which kids might get cavities. The goal is to improve how we assess cavity risk at a young age.
StockholmAges 3–3 - NCT05740033Recruiting
Closing the radial forearm donor site after mouth surgery
This study looks at how best to close the skin area on the forearm after surgeons take tissue to rebuild part of the mouth. If you need a radial forearm tissue reconstruction, you may be asked about outcomes afterward using English questionnaires.
Vancouver, British ColumbiaAges 18 years+ - NCT06943443Enrolling by invitation
Vitamin D and expander treatment for teens
This trial looks at whether vitamin D levels affect how well a special expander (MARPE) works to fix a narrow upper jaw in teens. If you are 15–18 and have a narrow upper jaw, you may be able to join.
Konya, MeramAges 16–18 - NCT06943846Recruiting
Platelet gel for healing after tooth removal in older adults
This study tests if a gel made from your own blood can help your gums heal faster after a back tooth is removed. It is for patients getting dental care at the University of Nebraska Medical Center.
Lincoln, NebraskaAges 14–80 - NCT06949436RecruitingPhase 2
Early Gamma Knife for Trigeminal Neuralgia
This study tests if giving Gamma Knife radiosurgery (a precise beam of radiation) early after diagnosis can help control facial pain from trigeminal neuralgia. It is for people who have not yet tried many medications or are satisfied with their current pain control.
Edmonton, AlbertaAges 18 years+ - NCT06944028Enrolling by invitation
Stepwise cavity treatment for deep decay in young teeth
This trial tests a gentler way to remove deep cavities in young permanent molars or premolars, aiming to save more of the tooth and protect the nerve. It may be an option for children and teens with deep decay that hasn't reached the pulp.
StockholmAges 8–19 - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.