Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07287826RecruitingPhase 4
Steroid mouthwash to prevent mouth sores during chemo
This trial tests if using a steroid mouthwash can prevent painful mouth sores caused by certain chemotherapy drugs. It aims to help patients who are starting or already receiving chemotherapy known to cause mouth sores.
Baton Rouge, LouisianaAges 18 years+ - NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT07290621RecruitingPhase 2
Toripalimab with standard treatment for HPV-positive throat cancer
This study tests adding a new immunotherapy drug (toripalimab) to standard chemo for HPV-positive throat cancer. It aims to see if this combination works better than chemo alone for patients whose cancer has spread to nodes but not to other parts of the body.
Chicago, IllinoisAges 18 years+ - NCT07290790Recruiting
Trimline Aligner Accuracy Study
This trial tests SureSmile clear aligners to see how accurately they fix common bite problems like crowding, spacing, and overbite. You may be able to join if you need mild to moderate orthodontic treatment.
Fresno, CaliforniaAges 18 years+ - NCT07292870Recruiting
Biological treatments for deep gum bone defects
This trial tests whether biological agents can help heal deep gum bone defects that remain after standard non-surgical cleaning. It may be an option for people who still have deep pockets around their teeth and need a minimally invasive surgical procedure.
Leuven, Vlaams BrabantAges 18 years+ - NCT07293013Recruiting
Olive oil mouthwash for mouth sores during cancer treatment
This study tests whether using an olive oil mouthwash can help prevent or reduce mouth sores caused by radiation and chemotherapy for head and neck cancer. If you are starting treatment, you may be able to join and receive the mouthwash to see if it helps keep your mouth healthier.
Chiayi City, Chia-Yi CityAges 20 years+ - NCT07293481Recruiting
Finding markers for gum disease diagnosis
This study looks for new markers in the body that could help diagnose gum disease. It's for adults with mild gum problems who haven't had recent dental treatment or antibiotics.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT07293962RecruitingPhase 2
Liquid S-PRF for gum disease treatment
This study tests whether a special liquid made from your own blood (called liquid S-PRF) can improve gum health during deep cleaning for people with advanced gum disease. It lasts 3 months and may help reduce inflammation and promote healing without surgery.
Jenjarum, SelangorAges 18–65 - NCT07295197Recruiting
Oral signs for early eating disorder screening
This study looks at signs in your mouth that might help detect eating disorders early. Dentists will examine your teeth, gums, and oral tissues to see if they can spot clues that could lead to faster diagnosis and care.
BolognaAges 18–40 - NCT07296250Recruiting
Tracking cancer cells after chemoradiation for oral cancer
This trial studies whether detecting circulating tumor cells in the blood after chemoradiation can help predict outcomes for people with oral cancer that has spread to lymph nodes. It may help doctors better monitor the disease.
Taoyuan CityAges 1.5 years–90 years - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07297836Recruiting
Dentist practices for treating baby teeth in France
This study surveys dentists in France about how they treat non-vital (nerve-damaged) baby teeth. It aims to understand current professional practices.
StrasbourgAges 18 years+ - NCT07298057RecruitingEarly Phase 1
Dental implant study for people with diabetes
This study tests if adding an antibiotic (Arestin) to standard gum cleaning can improve gum health and blood sugar control in people with type 2 diabetes.
Cleveland, OhioAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07301918Recruiting
Comparing two expanders for crossbite in children
This trial compares two types of expanders (Leaf Expander vs. Hyrax Expander) to fix crossbites in children who still have some baby teeth. The goal is to see which device works better and is more comfortable.
CairoAges 6–12 - NCT07302581Recruiting
Study of dental implants with natural ligament for single tooth replacement
This trial tests a new type of dental implant that includes a ligament (like a natural tooth's shock absorber). It's for people who need to have a single front or side tooth pulled and have healthy gum and bone around the area. The goal is to see if this implant works well and stays healthy over time.
Kōriyama, FukushimaAges 18 years+ - NCT07303023RecruitingPhase 3
Personalized neck radiation to prevent cancer spread
This trial tests whether a personalized radiation plan for the neck can prevent cancer from spreading in people with nasopharyngeal carcinoma. It's for those whose cancer hasn't spread beyond the head and neck area.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07304596Recruiting
Oral health impact questionnaire for periodontitis patients
This study evaluates a Hindi questionnaire that measures how periodontitis affects your daily life. It is designed for patients with periodontitis who can fill out forms on their own.
Rohtak, HaryanaAges 18 years+ - NCT07306533Recruiting
Menstrual phase and dental pain relief study
This trial tests whether the phase of your menstrual cycle affects how well local anesthesia works for a root canal. It may help dentists give you better pain control based on your cycle.
New Delhi, Delhi(दिल्ली)Ages 18–45 - NCT07309653Recruiting
A new single-shade filling for broken front teeth in kids
This study is testing a new single-shade filling material for broken front teeth in children. We want to see if the color matches well, stays strong, and makes kids and parents happy with the look.
BangkokAges 6–15 - NCT07310212Recruiting
Comparing two root canal techniques for pain and success
This study compares two methods of filling a root canal after cleaning it: a traditional lateral condensation technique and a newer warm vertical obturation technique. The goal is to see which one causes less pain afterward and has a better success rate.
Amman, Amman GovernateAges 18 years+ - NCT07311512Recruiting
Gum treatment and mouthwash study for gum disease
This trial tests if a professional gum cleaning combined with a special mouthwash can improve gum health and blood vessel function. It may help people with early gum disease who haven't had recent gum treatment.
Portsmouth, HampshireAges 30–75 - NCT07312045Recruiting
Gum health and healing after non-surgical treatment
This study looks at how certain blood and saliva measurements relate to gum disease and healing after a deep cleaning. It may help find better ways to track gum health.
Merkez, ErzincanAges 18–65 - NCT07312552Recruiting
Gum health, smoking, and saliva markers study
This study looks at how gum health and smoking affect certain proteins in your saliva. It may help researchers understand more about gum disease and inflammation.
IstanbulAges 18–65
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.