Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07314034Recruiting
Digital full-mouth dental restoration trial
This trial tests a fully digital, face-guided approach to replace missing teeth and fix bite or cosmetic issues. It may help if you need a complete mouth rebuild and are open to a modern digital treatment process.
Shibīn al Kawm, MenoufiaAges 20–45 - NCT07314580Recruiting
Transplanting premolars to replace lost front teeth in teens
This trial tests whether moving a back tooth (premolar) to replace a lost or damaged front tooth works well in young people aged 7–15. It aims to help avoid bridges or implants by using the patient's own tooth.
Barcelona, BarcelonsAges 7–15 - NCT07315607Recruiting
Study of same-day implant crowns made with digital planning
This trial tests a new digital planning and guided surgery method for placing and placing a temporary crown on a dental implant right after tooth removal. It aims to see how accurate these same-day, screw-retained crowns are, which could mean fewer visits and faster results for you.
Madrid, MadridAges 18 years+ - NCT07316023RecruitingPhase 2
Light therapy for gum disease treatment
This trial tests a new light treatment for gum disease using a special dye that targets and kills harmful bacteria. It may help if you have advanced gum disease and haven't had treatment recently.
CairoAges 36–50 - NCT07317570Recruiting
Body awareness therapy for jaw pain and function
This study tests whether body awareness therapy (gentle exercises that help you notice how your body moves and feels) can reduce jaw pain, improve function, and help with related emotional stress. It is for people with long-term jaw joint problems.
RizeAges 18 years+ - NCT07320417Recruiting
Preserving sinus lining during maxillary surgery
This study tests a modified surgery technique that keeps the sinus membrane intact while removing part of the upper jaw. It aims to reduce complications and help bone healing for patients with growths in the upper jaw that haven't spread to the sinus cavity.
ShanxiAges 18–75 - NCT07323433Recruiting
Chitosan dressing for pulp treatment in immature teeth
This trial tests a special chitosan dressing used during a partial root canal treatment (pulpotomy) for immature permanent front teeth. It may help the tooth continue to develop and heal without the need for more complex procedures.
MinyaAges 7–15 - NCT07325539RecruitingPhase 2
Radiation and immunotherapy with chemo for nose and throat cancer
This trial tests combining low-dose radiation with an immunotherapy drug (toripalimab) and chemotherapy for people whose nose and throat cancer has come back or spread. The goal is to see if this combination works better than standard treatments.
Guangzhou, GuangdongAges 18–65 - NCT07325604Recruiting
Electrical stimulation for facial weakness after stroke
This trial tests whether a gentle electrical stimulation (called NMES) can help people with facial weakness after a first stroke. You would do facial exercises during the stimulation to see if it helps you regain movement.
HammelAges 18 years+ - NCT07325747Recruiting
Immediate vs. delayed surgery for infected dental implants
This study compares getting surgery right away versus waiting for infected dental implants. If you have a failing implant with bone loss around it, this trial may help decide the best time to fix it.
Ann Arbor, MichiganAges 18 years+ - NCT07326358Recruiting
AI help for doctors finding problems in nose and throat exams
This study uses artificial intelligence to help doctors better see and find issues during nose and throat camera exams. If you are getting this exam and agree to participate, your images may be checked by the AI system to see if it can improve detection.
ShanghaiAges 18 years+ - NCT07327216RecruitingPhase 3
Comparing two inhalations for mouth sores from cancer treatment
This trial tests if an inhaled medication called Sapylin can prevent or reduce severe mouth sores caused by chemoradiation, compared to a standard steroid inhalation. It is for people with advanced nasopharyngeal cancer who have not yet started treatment.
Zhanjiang, GuangdongAges 18–75 - NCT07327658Recruiting
Periodontal treatment and pocket depth changes
This trial looks at how much gum pocket depth decreases after standard gum disease treatment. It is for people with advanced periodontitis who are otherwise healthy.
Konya, KonyaAges 18–65 - NCT07328269Recruiting
Mulligan vs Maitland technique for jaw pain relief
This trial compares two manual therapy methods (Mulligan and Maitland) to improve jaw movement and reduce pain in people with temporomandibular joint (TMJ) dysfunction. If you have limited jaw opening or jaw pain, you may be able to join.
Islamabad, Punjab ProvinceAges 19–44 - NCT07328854RecruitingPhase 3
Lower versus standard radiation in stage II nasopharyngeal cancer
This trial compares a lower dose of radiation (40.2 Gy) to the standard dose (49.2 Gy) for patients with stage II nasopharyngeal carcinoma that has shrunk after initial chemoimmunotherapy. The goal is to see if the lower dose works just as well while potentially causing fewer side effects.
Hefei, AnhuiAges 18–75 - NCT07328841RecruitingPhase 3
Lower radiation dose study for advanced nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with advanced nasopharyngeal cancer that shrank after chemotherapy and immunotherapy. The goal is to see if a lower dose works just as well with fewer side effects.
Guangzhou, GuangdongAges 18–70 - NCT07330089Recruiting
Sealant study: pit and fissure sealing for kids
This trial will see if dental sealants work better on healthy teeth versus those with early signs of decay. If you have a child between 7 and 18 with fully grown back molars that have no fillings, they may be able to join.
Islamabad, FederalAges 7–18 - NCT07331935Recruiting
Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia
This study tests whether a cream containing coenzyme Q10 and curcumin can help treat a common mouth condition called oral leukoplakia (a white patch that can sometimes turn into cancer). It is for people with a specific type of white patch that is not severe and can be easily reached with a cream.
AlexandriaAges 40 years+ - NCT07332247RecruitingPhase 2
Immunotherapy plus chemo then immediate vs selective re-radiation for advanced recurrent NPC
This trial is for people with nasopharyngeal cancer that has come back in the same area. It tests whether giving additional radiation right after chemo plus immunotherapy works better than waiting to see if more radiation is needed later.
Guangzhou, GuangdongAges 18–70 - NCT07336082Recruiting
Sensory training vs. exercise for awake teeth clenching
This study compares two non-drug treatments—sensory training and exercise therapy—to help people who clench or grind their teeth while awake. It aims to reduce jaw pain and improve daytime function.
AydinAges 18–45 - NCT07337057Recruiting
Standardized dental implant outcomes
This study is creating a standard way to measure the success of dental implants. It is for people who need a new implant or a replacement implant, and who do not have major health or mouth problems that would complicate the procedure.
Rotterdam, South HollandAges 18–75 - NCT07337109Recruiting
Study on tooth sensitivity and quality of life
This study looks at how tooth sensitivity affects your daily life and what treatments people use. It is for people who have recently started having sensitive teeth and have tried products for it.
Las Vegas, NevadaAges 18 years+ - NCT07339605Recruiting
Gum bone regeneration with hyaluronic acid vs enamel matrix
This trial compares two treatments to help regrow bone and gum tissue around teeth with deep bone defects. It tests if hyaluronic acid works as well as enamel matrix derivative, both applied during a minimally invasive procedure.
Valencia, ValenciaAges 18 years+ - NCT07340008Recruiting
Comparing medicines for calm stitch removal in children after cleft surgery
This study compares three different medicines (ketamine, nalbuphine, and dexmedetomidine) to help keep children calm and comfortable while their stitches are removed after cleft surgery. It may help find the best way to reduce pain and anxiety in young children during this procedure.
LjubljanaAges 6 months–3 years
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.