Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07671326Recruiting
Bioceramic vs calcium hydroxide for infected molars
This study compares two types of medication placed inside a root canal to fight infection. It may be an option if you have an infected lower molar and are in generally good health.
Istanbul, IstanbulAges 18–65 - NCT07671963Recruiting
Bone Graft Options for Gum Disease Surgery
This trial tests two bone-replacement materials (a synthetic bone substitute and a natural bone graft) placed during gum surgery to see which one better helps rebuild bone and gum support around teeth with deep pockets.
Cagliari, ItalyAges 18–80 - NCT07645417Enrolling by invitation
Comparing Wires for Moving Upper Canine Teeth During Braces
This study tests two types of orthodontic wires to see which one more effectively moves your upper canine teeth backward when you're already wearing fixed braces. The goal is to find the best method for straightening your bite with minimal side effects.
DhakaAges 1.3 years–2.9 years - NCT07644676Enrolling by invitation
Comparing Bonding Methods for Dental Crowns
This study tests different ways to attach a crown to your back tooth to see which method works best and lasts longest. If you need a single crown and have healthy teeth and gums, you may be able to participate.
Hörby, Skåne CountyAges 18 years+ - NCT07640074Enrolling by invitation
Coconut-based filling material for children's cavities
This study tests a new filling material made from coconut to repair cavities in children's primary (baby) teeth. Researchers want to see how well this material works compared to traditional fillings.
IslamabadAges 5–9 - NCT07619729Enrolling by invitationPhase 4
Oral Health Program for People With Type 2 Diabetes
This study tests whether a text-message and online program about caring for your teeth and gums can help people with type 2 diabetes. Researchers want to see if better oral health habits improve overall health outcomes.
Long Island City, New YorkAges 18 years+ - NCT07615361Enrolling by invitation
Tooth Graft and Laser Therapy for Dental Implants
This study tests whether material from extracted teeth, combined with low-level laser treatment, can help bone heal better before dental implants are placed. The goal is to improve implant success and reduce bone loss after tooth removal.
Istanbul, UskudarAges 18–65 - NCT07606638Enrolling by invitation
Pain Relief Options for Oral Cancer Patients
This study compares two different pain management approaches for people with oral cancer: opioid medication versus a combination of pregabalin (a nerve pain reliever) and naproxen sodium (an anti-inflammatory painkiller). The goal is to see which approach works better and is safer for controlling cancer-related pain.
Lahore, Punjab ProvinceAges 18 years+ - NCT07604142Enrolling by invitation
Donor bone to close sinus opening after tooth extraction
This trial tests using sterilized donor bone to repair a hole that opens into your sinus when a severely damaged upper back tooth is removed. The goal is to rebuild the bone so a dental implant can be placed safely later.
TantaAges 20 years+ - NCT07587606Enrolling by invitation
Studying Healing Tissue in Deep Gum Pockets
This study examines how gum tissue heals in deep pockets that remain after standard gum disease treatment. Researchers will collect small samples of healing tissue to better understand gum disease and improve future treatments.
Roma, RomaAges 18–75 - NCT07580534Enrolling by invitation
Dental implant overdentures using new attachment systems
This study compares traditional and 3D-printed dental implants with new attachment systems for people who have lost all their teeth. The goal is to see which approach works best for keeping dentures stable and comfortable long-term.
AsyutAges Up to 70 years - NCT07579338Enrolling by invitation
Bacteria and Gum Health: A Detection Study
This study examines specific bacteria in your mouth to understand their role in healthy gums versus gum disease. Researchers will collect samples to measure bacterial levels and help improve how gum disease is diagnosed and treated.
Hillah, BabelAges 30 years+ - NCT07573761Enrolling by invitation
Tooth Grafts to Help Bone Grow for Dental Implants
This trial tests whether material made from extracted teeth can help bone regrow in the jaw after tooth removal, so you can get a dental implant. Researchers will compare this new approach to see if it works better for rebuilding bone in areas where teeth need to be replaced.
Istanbul, UskudarAges 18–65 - NCT07566936Enrolling by invitation
Digital vs. Traditional Splints for Jaw Joint Disorders
This study compares two types of custom-made jaw splints—one designed using digital technology and one made the traditional way—to see which better relieves jaw pain and improves mouth opening in people with temporomandibular disorder (TMD), a common condition affecting the jaw joint.
Islamabad, IslamabadAges 18–40 - NCT07556211Enrolling by invitation
How Jaw Clenching Affects Athlete Performance
This study looks at whether jaw clenching during sleep or stress affects muscle strength and performance in swimmers and handball players. Researchers want to understand if treating jaw clenching might help athletes perform better.
LiègeAges 18–35 - NCT07519382Enrolling by invitation
Comparing two types of tooth-covering restorations
This study compares two different ways to restore damaged teeth using computer-designed tooth coverings (onlays). You would receive one type of restoration and have it checked regularly to see how well it works and lasts.
Budapest, BudapestAges 18 years+ - NCT07514208Enrolling by invitation
Headache Sensitivity and Pain Testing Study
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
Barcelona, BarcelonaAges 18 years+ - NCT07491627Enrolling by invitation
Nicotine's effect on gum disease treatment in smokers and non-smokers
This study looks at how smoking and nicotine affect the success of gum disease treatment. It compares results between smokers and non-smokers who have gum disease.
Liège, LiegeAges 18 years+ - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT07477873Enrolling by invitation
Emotions and jaw surgery recovery study
This study looks at how patients feel emotionally and physically before and after jaw surgery. It uses special software and questionnaires to track emotions, and checks the jaw joint and muscles after surgery. The goal is to see how these relate to recovery in patients having planned jaw surgery.
Kaunas, KaunoAges 18 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT07437924Enrolling by invitation
Bruxism and pelvic floor health in young women
This study looks at whether teeth grinding (bruxism) is linked to pelvic floor muscle function in young women. If you are 18–30 and either grind your teeth or do not, you may help researchers understand this connection.
KonyaAges 18–30 - NCT07436325Enrolling by invitation
Comparing gum health for two types of baby tooth crowns
This trial compares how gum health holds up with zirconia vs. stainless steel crowns on baby molars in children aged 3–7. It helps find which crown type may be better for keeping gums healthy.
Buraidah, Al-Qassim ProvinceAges 3–7 - NCT07426224Enrolling by invitation
Blood sugar screening for advanced gum disease patients
This trial checks if treating advanced gum disease at a specialist clinic can help find hidden high blood sugar and support you in managing your overall health.
StockholmAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.