Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07749053Recruiting
Endometriosis research study for women aged 18 to 45
This study gathers information from women with endometriosis and healthy women to better understand the condition. By participating, you help researchers learn more about endometriosis, which may lead to better care in the future.
Guangzhou, GuangdongAges 18–45 - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT07750626Recruiting
Vibration and ShotBlocker for injection pain in children
This study tests two methods to reduce pain and fear during a shot in the emergency department. It compares using a vibration device or a ShotBlocker device against standard care.
BurdurAges 5–10 - NCT07750236Recruiting
Stress ball for easing fear and pain during allergy testing
This trial gives children a stress ball to hold during their allergy skin test, to see if it helps reduce fear, anxiety, and pain, and makes the experience more satisfying for the family.
TarsusAges 4–10 - NCT07745881Recruiting
Pain relief after lung cancer surgery
This trial tests a nerve block that may reduce pain after surgery for lung cancer. It's a technique that numbs a specific area in the back to help you feel more comfortable during recovery.
Nanjing, JiangsuAges 18–80 - NCT07674836Recruiting
Comparing two nerve blocks for chronic pain after breast surgery
This study tests two types of nerve blocks (SPSIP and ESP blocks) to see which one works better for long-term pain after a single-sided breast surgery like mastectomy. It aims to find a safer, more effective way to manage chronic pain after surgery.
İzmit, KocaeliAges 18–65 - NCT06902636Recruiting
Trauma care program for older adults living alone
This trial tests a special care program for older adults who live alone and have limb injuries. It aims to help them recover safely at home using smartphone support for three months.
Kaohsiung City, KaohsiungAges 65 years+ - NCT07541040Recruiting
Nerve Blocks for Breast Surgery Pain Relief
This trial tests two different nerve-block techniques to reduce pain after breast surgery. The study compares a serratus block with an ESP block—both are injections of numbing medication near nerves—to see which works better for managing pain without heavy opioid use.
İzmit, KocaeliAges 18–65 - NCT07750639Enrolling by invitationPhase 4
Reducing painkiller use after hand surgery
This study tests a new approach to prescribing fewer opioid pain pills after hand, wrist, or elbow surgery. It aims to help reduce the risk of opioid misuse while still controlling pain after surgery.
Orlando, FloridaAges 18 years+ - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07032480Recruiting
Sleep, Neck Pain, and Depression Study
This study looks at how sleep problems, neck pain, and depression might be connected in healthy young adults. It aims to help understand these common issues better.
Istanbul, ÜsküdarAges 18–28 - NCT07154849RecruitingPhase 4
Preventing shivering after abdominal surgery with two IV drugs
This trial tests two intravenous medicines—hydrocortisone and dexmedetomidine—to see which one works better at preventing shivering after abdominal surgery. It may help you stay comfortable and recover more smoothly.
CairoAges 18–65 - NCT07048769RecruitingPhase 4
Pain relief shot for saline ultrasound of the uterus
This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.
Hartsdale, New YorkAges 18–50 - NCT07016971RecruitingPhase 1
CBG/CBD oil for nerve pain from chemotherapy
This trial tests whether a blend of CBG and CBD oils can help relieve nerve pain, tingling, or weakness caused by platinum-based chemotherapy in people with certain gastrointestinal cancers. If you have had colorectal, biliary, pancreatic, esophageal, gastric, or small intestinal cancer and completed chemo in the last 2 years, you may be able to join.
Hershey, PennsylvaniaAges 21 years+ - NCT07088146RecruitingPhase 4
Dexamethasone to prolong spinal anesthesia in C-section
This study tests whether giving dexamethasone (a steroid) during spinal anesthesia can make the numbness last longer during a planned C-section. It may help reduce the need for extra pain medicine after surgery.
Rawalpindi, Punjab ProvinceAges 16–40 - NCT07067125Recruiting
Augmented reality physiotherapy for teens with scoliosis
This study explores how teens with scoliosis feel about using augmented reality (a technology that overlays digital images on the real world) during their physical therapy sessions. It aims to understand if AR makes therapy more engaging or helpful.
GaziantepAges 10–18 - NCT07056244Recruiting
Comparing two pain medicines for children’s hernia surgery
This study tests whether adding dexmedetomidine or dexamethasone to the standard numbing medicine (bupivacaine) provides better pain relief for children getting hernia surgery. The medicine is given through a shot in the lower back (caudal epidural block) to help keep your child comfortable during and after the operation.
SohagAges 2–6 - NCT06990893Recruiting
Oliceridine vs morphine for pain after lumbar surgery
This study compares a new pain medicine called oliceridine with morphine or sufentanil to see which works better after lumbar spine surgery. It aims to find a safer and more effective way to manage pain after your operation.
Anqing, AnhuiAges 18–65 - NCT06972680Enrolling by invitation
Finding the best dose for a shoulder block before surgery
This trial tests different volumes of a long-lasting numbing medicine (Exparel) injected around the shoulder nerves before arthroscopic surgery. The goal is to find the dose that provides the best pain relief.
Jiaxing, ZhejiangAges 18 years+ - NCT06992375Recruiting
Shoulder manipulation study for volleyball players
This trial tests a shoulder manipulation technique in healthy volleyball players to see if it improves shoulder function and performance. It may help if you play regularly and haven't had recent injuries or surgeries.
GdanskAges 18–30 - NCT06964282Recruiting
Comparing Two Nerve Blocks for Hip Replacement Pain Relief
This study compares two types of nerve blocks (iliopsoas block and PENG block) to see which one provides better pain relief and recovery after hip replacement surgery. If you are having a hip replacement with spinal anesthesia, you may be a good candidate.
LiègeAges 18 years+ - NCT06966557Recruiting
Nerve block for chronic jaw pain
This trial tests a nerve block treatment for people with long-term jaw pain that hasn't improved with other treatments. It aims to see if this injection can help reduce pain.
Haifa, NorthAges 18 years+ - NCT06979583Enrolling by invitation
Stent and sheath size and pain after kidney stone surgery
This study compares whether the size of the stent and the sheath used during kidney stone surgery affects how much pain you feel afterward. If you are having a stone removal procedure and will get a stent with a string, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06910982Enrolling by invitation
Yoga and Mindfulness for Chronic Low Back Pain
This study tests whether a combination of yoga and mindfulness exercises can help reduce chronic lower back pain. It compares this program to usual care, and may be a good fit if your pain is bothersome but you are not too afraid that moving will make it worse.
Karachi, SindhAges 25–45
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.