Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06813495Recruiting
ACT for injury prevention in nurses and aides
This study tests a program called Acceptance and Commitment Therapy (ACT) to help nurses and nursing aides prevent injuries at work. If you work in a long-term care facility in specific areas of the US or Thailand, you may be able to join.
Bowling Green, OhioAges 18 years+ - NCT06813937Recruiting
Magnetic stimulation for feeling in upper limb amputation
This study tests whether magnetic stimulation can improve sensation in people who have lost an upper limb. It may help restore feeling in the residual limb.
MoscowAges 18–65 - NCT06816056Recruiting
Foot therapy for hemophilia ankle arthritis
This study tests if manual therapy can help patients with hemophilia who have arthritis in their ankle. It seeks to improve joint health and reduce pain.
MurciaAges 18–65 - NCT06816082Recruiting
Online therapy for chronic pain rehabilitation
This trial tests if adding internet-based acceptance therapy to standard pain rehabilitation helps adults with chronic pain. It is for patients at the Linköping pain clinic who have internet access.
Linköping, Östergötland CountyAges 18 years+ - NCT06817018RecruitingPhase 2
Ginger root extract for chronic sciatica pain
This study tests whether a ginger root extract can reduce pain in people with long-term sciatica. If you have had sciatic pain for at least 3 months and are not on blood thinners, you may be able to join.
Lubbock, TexasAges 18–85 - NCT06817135Recruiting
Shoulder exercises for breastfeeding neck pain
This trial tests if special shoulder-blade (scapular) exercises can help reduce neck pain in mothers who are exclusively breastfeeding. The exercises are simple and designed to strengthen the muscles that support your neck while you hold your baby.
Giza, DokkiAges 18–35 - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06818175Recruiting
Study of back muscle tissue and treatment for low back pain
This study looks at the tissue in your lower back using ultrasound and physical exams. It tests a treatment to see if it helps people with new or long-term low back pain, and also compares results to people without pain.
Blacksburg, VirginiaAges 18–50 - NCT06818396Recruiting
Pain relief for hip surgery: comparing two methods
This study compares two ways to manage pain during hip surgery: a nerve block in the groin area versus a spinal medication. The goal is to find which approach offers better pain control with fewer side effects.
CairoAges 21 years+ - NCT06819696Recruiting
Comparing two ACL reconstruction surgery methods
This trial compares two ways of doing anterior cruciate ligament (ACL) reconstruction surgery: using a tourniquet to control bleeding, or using a special sheath that allows fluid to flow in and out. The goal is to see which method works better during surgery.
Reims, MarneAges 18 years+ - NCT06821217Recruiting
App-based support for endometriosis quality of life
This trial tests whether using a smartphone app can improve quality of life for people with endometriosis. You'll use the app to track symptoms and get support, and researchers will see if it helps you feel better.
BernAges 18 years+ - NCT06821516Recruiting
Comparing two nerve blocks for hip replacement pain
This study compares two different nerve block techniques to manage pain after a total hip replacement. The goal is to find out which method provides better pain relief and recovery.
Istanbul, Türki̇yeAges 18 years+ - NCT06824337Recruiting
Walking program for healthy new mothers
This study tests a walking program for new mothers who had a healthy, full-term pregnancy. It uses a mobile phone to help you track your steps and recover safely.
NiğdeAges 1.5 years–35 years - NCT06825390Recruiting
Ear stimulation and brain imaging for chronic low back pain
This study tests if a non-invasive ear stimulation technique can change brain activity linked to chronic low back pain. You would have a brain scan before and after the treatment to see how your brain responds.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06825650Recruiting
Turkish adaptation of a pain questionnaire
This study aims to adapt a questionnaire about pain into Turkish and check if it works well. Researchers want to see if the questions are understandable and reliable for people with certain types of pain.
Ankara, AltındağAges 18 years+ - NCT06827730Recruiting
Ultrasound for chest or belly pain in the ER
This study uses a quick bedside ultrasound (called PoCUS) to help doctors diagnose chest or belly pain in the emergency room. If you join, you'll get this ultrasound early in your visit to see if it helps find the cause of your pain faster and more accurately.
BrusselsAges 18 years+ - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT06829875Recruiting
Access to muscle and joint therapy services
This study looks at how quickly people get appointments for muscle and joint problems. It includes patients waiting for foot therapy, occupational therapy, or physical therapy.
Cardiff, WalesAges 18 years+ - NCT06830876Recruiting
Testing muscle stimulator for pain and function after leg amputation
This trial tests if a noninvasive electrical stimulator (NMES) placed on the residual leg can reduce pain and improve muscle and function in people with a below-knee amputation. It aims to offer a drug-free option for managing chronic limb pain.
Pittsburgh, PennsylvaniaAges 18–100 - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17 - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65 - NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.