Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06971601Recruiting
Testing physical exams for kneecap fat pad syndrome
This study aims to find out if simple physical exam tests can accurately diagnose impingement of the fat pad behind the kneecap. You would get a clinical exam and an MRl to compare the results, so researchers can see which tests best identify the problem.
Saint-MauriceAges 18–70 - NCT06820528Recruiting
Thumb arthritis surgery: is in-clinic therapy needed?
This trial compares recovery after thumb joint surgery with or without in-clinic physical therapy. It aims to see if patients can recover just as well with home exercises alone, which could reduce travel and costs.
Columbia, MissouriAges 18 years+ - NCT06947642Recruiting
Comparing numbing blocks for breast surgery
This study compares three ways of numbing the chest muscle and rib area with ultrasound during breast surgery to see which one works best for pain control. If you are having breast surgery and want to help improve pain management, this might be a good fit.
Tanta, El-GharbiaAges 21–65 - NCT06834113Recruiting
Testing pain relief from HIV shot location and virtual reality
This study looks at whether changing where you get your HIV injection (in the buttock area) and using a virtual reality headset during the shot can reduce pain. It is for people whose HIV is well-controlled with the injectable medicines cabotegravir and rilpivirine.
Orléans, LoiretAges 18 years+ - NCT06839690Recruiting
Comparing two exercises for De Quervain tenosynovitis
This study compares two types of exercises (sub-maximal isometric training vs eccentric training) to see which one helps more with thumb pain and tenderness caused by De Quervain tenosynovitis. You may qualify if you have had thumb pain for at least 3 weeks and meet certain diagnostic tests.
Rawalpindi, Punjab ProvinceAges 21–50 - NCT06879860Enrolling by invitation
Comparing stitch vs no stitch for groin hernia repair
This study compares two ways to fix a mesh during groin hernia surgery: 3D patch with one stitch versus no stitches at all. It aims to see which method leads to less long-term pain and fewer hernias coming back. If you have a first-time, moderately large groin hernia, you may qualify.
Nanchong, SichuanAges 18–80 - NCT06855199Recruiting
Epidural pain block for children's lower body surgery
This study tests a numbing injection (caudal epidural block) to improve pain relief during children's lower body surgeries. It is for children who are generally healthy (ASA 1–2) and having certain procedures.
Sivas, SivasAges 1–6 - NCT06886802Recruiting
Study of a new neck surgery for spinal stenosis
This study is looking at a new, less invasive neck surgery for people with cervical spinal stenosis (narrowing of the spinal canal in the neck). It tests whether this surgery helps relieve symptoms like pain, numbness, or weakness in the arms or legs.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT06852378Recruiting
Pain blocks for hip fracture surgery
This study compares two types of nerve blocks to see which one provides better pain relief during hip fracture surgery. It may help reduce pain and improve recovery after your procedure.
CairoAges 18–65 - NCT06840262Recruiting
Nerve surgery for pain after cancer amputation
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Houston, TexasAges 18 years+ - NCT06888934Recruiting
Testing a new toe implant for arthritis and crooked toes
This study tests a new implant called Lync® to fix arthritis or crooked toes (like hammer, claw, or mallet toes). The implant helps straighten the toe bone and may reduce pain.
LyonAges 18 years+ - NCT06845696Recruiting
Comparing exercises vs. taping for forward head posture
This study compares two treatments—Brugger's relief exercises and kinesio taping—to see which one improves forward head posture better. Forward head posture means your head sits too far forward from your shoulders, which can cause neck strain.
Islamabad, FederalAges 20–40 - NCT06858293Recruiting
Imagining exercises to boost knee strength after ACL surgery
This study tests whether imagining yourself doing exercises can help you regain strength in your thigh muscle after ACL surgery, and if it's something people can stick with during physical therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06846983Recruiting
Testing a new way to predict numbing success for children's surgery
This trial checks if a simple monitor reading (peripheral perfusion index) can help doctors know if a numbing shot (caudal block) will work well for children having belly or pelvic surgery. It may lead to better pain control during and after surgery.
Cairo, AbbasiaAges 1–5 - NCT06830655Enrolling by invitation
Climbing performance and body factors study
This study looks at how mobility, balance, and fatigue affect climbing performance. If you are a healthy climber, you may help researchers understand what makes a better climber.
Gdansk, GdańskAges 15–45 - NCT06823349RecruitingPhase 4
Pain relief study for normal labor
This trial compares a single injection of pain medicine into the spinal fluid to other methods during normal labor. It aims to see how well it works for women in active labor with a single, full-term baby in head-down position.
AswānAges Any age - NCT06815393Recruiting
Comparing two pain relief methods for abdominal hysterectomy
This trial compares two different pain relief methods for women having abdominal hysterectomy (surgery to remove the uterus through a cut in the belly). It may help find a better way to manage pain after surgery.
Erzurum, YakutiyeAges 18–65 - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06777940Recruiting
Kegel exercises vs. muscle release for period pain
This study compares two methods to reduce period pain: Kegel exercises (pelvic floor exercises) and a hands-on technique to release muscle knots (trigger points) in the lower belly, back, and hip. It may help if you are a young woman with painful periods and have tender spots in those muscles.
Lahore, Punjab ProvinceAges 17–25 - NCT06783114RecruitingPhase 2/Phase 3
Testing a new Botox-like injection for arm stiffness after stroke
This study tests an investigational botulinum toxin injection (YY001) to reduce muscle stiffness in the arm after a stroke. It may help you move your arm more easily and improve daily tasks.
Hefei, AnhuiAges 18–75 - NCT06752486RecruitingPhase 1
Gabapentin for pain after laser eye surgery
This study tests if a medicine called gabapentin can safely reduce pain after a type of laser eye surgery called surface ablation. It's looking for adults with stable vision who are generally healthy and have not had previous eye procedures.
GizaAges 18–65 - NCT06774547Recruiting
Early jumping exercises for leg tendon pain
This study tests whether adding jumping exercises early helps people with long-lasting leg tendon pain recover faster.
AalborgAges 18–50 - NCT06658210Recruiting
Soft tissue massage and pelvic exercises for pelvic scar tissue
This study tests whether gentle massage and pelvic floor exercises can help relieve pain and discomfort from pelvic scar tissue (adhesions) in women who have had a hysterectomy. It may be an option for you if you are married, between 40 and 60, and healthy enough for these treatments.
Lahore, Punjab ProvinceAges 40–60 - NCT06671743RecruitingPhase 3
Medication before root canal to reduce pain
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
AjmanAges 20–50
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.