Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07798830Recruiting
Nerve block options for pain relief after hip replacement surgery
This study compares two types of nerve blocks to see which one provides better pain relief after hip replacement surgery. The blocks are given during the surgery to help reduce pain after the operation.
Tanta, El-GharbiaAges 18 years+ - NCT07793214Recruiting
Whole-body infrared hyperthermia for advanced solid tumors
This study looks at how well a treatment called whole-body infrared hyperthermia works for people with advanced solid tumors. The treatment uses heat to warm the whole body and may help fight cancer. The study will review medical records of people who already had this treatment at Zhejiang Hospital, and some people may join going forward.
Hangzhou, ZhejiangAges Any age - NCT07797374Recruiting
Nausea, vomiting, and pain after weight-loss surgery
This study looks at how patients feel after weight-loss surgery, specifically nausea, vomiting, and pain. It uses national registry data to understand these symptoms better, which may help improve care for future patients.
SundsvallAges 18 years+ - NCT07800403Recruiting
Nanoparticle disinfection for root canal infection in diabetes
This trial tests a new disinfection approach during root canal treatment for people with type 2 diabetes who have an infected front tooth. It aims to improve the effectiveness of the cleaning step, which may help treat the infection better.
MinyaAges 18–40 - NCT07798180Recruiting
Ear stimulation for belly pain in teens
This study tests a small earpiece that sends gentle signals to help reduce belly pain in teens with disorders of the gut-brain interaction. It may offer a drug-free way to manage pain.
Columbus, OhioAges 12–18 - NCT07794852Enrolling by invitation
Ultrasound-guided spinal anesthesia for prostate surgery
This study tests a new way to give spinal anesthesia (numbing medicine injected in your back) for prostate surgery. It uses ultrasound to measure the fluid space around your spinal cord to find the right dose, which may make the anesthesia safer and more effective.
IstanbulAges 40 years+ - NCT07796399RecruitingPhase 2/Phase 3
Comparing two pain blocks for children after chest surgery
This study compares two types of nerve blocks to see which provides better pain relief for children after chest surgery. The goal is to reduce pain and improve recovery.
Cairo, EgyptAges 5–18 - NCT07799155Recruiting
Epidural steroid injection for leg pain from nerve compression
This study tests a common pain-relieving injection for people with nerve pain in the lower back and leg caused by a pinched nerve. It aims to see how well the injection reduces pain and improves quality of life.
Istanbul, IstanbulAges 18–65 - NCT07797309Enrolling by invitation
Privacy drape for vaginal exams
This study tests a special drape that helps keep you covered and private during a vaginal exam. It may make the exam feel more comfortable and respectful.
OsmaniyeAges 18 years+ - NCT07800364Recruiting
Tizanidine before leg surgery for better pain and sleep
This study tests whether taking a muscle relaxant called tizanidine before leg surgery improves pain control and sleep quality after the operation. It may help you recover more comfortably.
Tanta, Gharbia GovernorateAges 21 years+ - NCT07795697Recruiting
Remote rehab after spine surgery
This trial tests whether doing physical therapy at home using video calls or an app helps you recover as well as in-person rehab after spine surgery. It could make it easier for you to get the care you need without traveling.
KuopioAges 20–85 - NCT07794475RecruitingPhase 1/Phase 2
Trimetazidine for diabetic nerve pain
This trial tests whether the drug trimetazidine can improve nerve damage symptoms in people with type 2 diabetes and diabetic neuropathy. It also looks at how the drug affects a substance in the blood called endothelin-1, which may be involved in nerve damage.
CairoAges 18–65 - NCT07792629Recruiting
Mirror therapy for postpartum recovery
This trial tests whether using mirror therapy during labor can improve postpartum recovery. It is for women who are at least 18, can read and write Turkish, and are having a vaginal delivery without complications.
Ağrı, AğriAges 18 years+ - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06413381Recruiting
Endometriosis hormone therapy: who may not respond
This study looks for reasons why some people with endometriosis don't get pain relief from hormone medications. It aims to find out who might need a different treatment approach.
Bologna, BOAges 18–50 - NCT07790705Enrolling by invitation
Comparing two massage techniques after hip replacement
This study compares two types of massage therapy after hip replacement surgery to see which one works better for recovery. If you join, you will be randomly assigned to one of the two massage methods and will practice it at home for 6 weeks.
Cumming, GeorgiaAges 18 years+ - NCT07790471Recruiting
Recovery checklists after cesarean delivery
This study looks at how following a recovery plan after a planned cesarean birth affects how well mothers feel and recover. It involves filling out questionnaires before and after the surgery to track your recovery.
Bursa, NilüferAges 18 years+ - NCT07789301Recruiting
Predicting severe pain after planned cesarean with spinal anesthesia
This study looks at how to predict severe pain after a planned cesarean delivery done under spinal anesthesia. It aims to find factors that may help doctors better manage pain after surgery.
Bursa, NilüferAges 18–45 - NCT06536582Recruiting
Nutrition’s role in PRGF treatment for shoulder tendon pain
This trial studies how diet affects the success of a special blood-based treatment (PRGF) for shoulder tendon pain. It may help you heal better from tendinopathy.
MilanAges 18–70 - NCT07792044Enrolling by invitation
Pain relief after shoulder surgery
This study tests a numbing medicine injected near the shoulder to see if it gives better pain relief after arthroscopic shoulder surgery than the standard approach. It might help you recover with less pain and fewer side effects.
Jiaxing, ZhejiangAges 18 years+ - NCT07789340Recruiting
Radiofrequency treatment for knee osteoarthritis pain
This study compares two types of radiofrequency treatment to reduce knee pain from osteoarthritis. It may help people whose knee pain has not improved with other treatments like physical therapy or injections.
Tanta, El-GharbiaAges 50 years+ - NCT07790874Recruiting
Eye exercises for neck-related dizziness
This trial tests whether eye exercises can help reduce dizziness and neck pain in people with chronic neck-related dizziness that started without an injury. It may help you if your dizziness has lasted for at least 3 months and is linked to your neck.
Faisalābad, Punjab ProvinceAges 20–40 - NCT07784998Recruiting
Weight-bearing physiotherapy for knee osteoarthritis
This study compares how men and women respond to a special type of physiotherapy that uses gradual weight-bearing exercises to reduce knee pain and improve function. It may help you if you have moderate knee osteoarthritis and are looking for a non-surgical treatment option.
Gujar Khan, Punjab ProvinceAges 40–60 - NCT07785804Enrolling by invitation
Testing a smartphone app for preventing and treating low back pain in nurses
This study tests a smartphone app called SelfBack to see if it helps prevent and manage low back pain in nurses. If you join, you'll use the app and answer questionnaires online over some time.
Brussels, Brussels CapitalAges 18–18
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.