Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06999395Recruiting
Virtual program for pelvic pain with vestibulodynia
This study tests whether a virtual program can help reduce pelvic pain and improve sexual experiences in people with a specific type of pain called provoked vestibulodynia. It is a completely online program, so you can participate from home.
Kingston, OntarioAges 18 years+ - NCT06999772Recruiting
Combining brain stimulation with physiotherapy for chronic back pain
This study tests if adding a non-invasive brain stimulation technique to physiotherapy can help veterans with chronic low back pain. It aims to improve pain and function by targeting both the brain and the body.
Québec, QuebecAges 18–65 - NCT07000409Recruiting
Ultrasound-guided nerve block for shingles pain
This trial tests if a nerve block with betamethasone can reduce long-term shingles pain on the trunk. It may help people who still have pain more than 3 months after the rash appeared.
CairoAges 18–75 - NCT07001631Recruiting
EMDR for pain relief in children with sickle cell disease
This trial tests if EMDR therapy can help children with sickle cell disease reduce pain interference in daily life. If you or your child has sickle cell disease and experiences significant pain, this study may offer a new way to manage it.
AmsterdamAges 6–18 - NCT07001566Recruiting
Neck nerve issues and shoulder function after rotator cuff repair
This study looks at how neck-related nerve problems (cervical radiculopathy) affect shoulder function in people who have had rotator cuff repair surgery. It aims to understand if neck issues can slow recovery or make it harder to use your arm normally.
Istanbul, IstanbulAges 41–65 - NCT07001709RecruitingPhase 4
How abiraterone affects oxycodone in prostate cancer
This study looks at how a common prostate cancer drug (abiraterone) affects how the body processes a painkiller (oxycodone). Men with prostate cancer who take abiraterone will be compared with those who do not, to see if the painkiller works differently.
Deventer, OverijsselAges 18 years+ - NCT07002541Recruiting
Nerve block comparison for breast surgery pain
This study tests two different nerve-block methods (PECS-II and ESP) to see which better reduces painkiller use during breast surgery. A special monitor guides how much pain medicine you need. The goal is to help you recover with less opioid side effects.
IstanbulAges 18–80 - NCT07002853Recruiting
Nature walks for chronic back pain in older adults
This trial tests whether spending time in nature can help older adults with long-term low back pain feel better and move more easily. If you are 65 or older and have had back pain for at least three months, you may be able to join.
Saguenay, QuebecAges 65 years+ - NCT07002944Recruiting
Testing nerve treatment for shoulder pain after mastectomy
This study compares two types of pulsed radiofrequency (a minimally invasive treatment using radio waves) to see which better relieves shoulder pain in women who have had a mastectomy. It's for women who still have pain despite taking a high dose of tramadol.
CairoAges 18–65 - NCT07003113Recruiting
Blood flow therapy for knee and back pain
This study tests a treatment called ischemic preconditioning, which uses a blood pressure cuff to temporarily restrict blood flow to your leg. It may help reduce pain from osteoarthritis in the knee or chronic back pain.
Chicago, IllinoisAges 50 years+ - NCT07004166Recruiting
New injection techniques to reduce pain and leakage
This study tests two different injection methods (TPR and Z-track) to see if they cause less pain and less medication leakage when giving the painkiller diclofenac sodium into the hip muscle.
SivasAges 18–40 - NCT07004634Recruiting
Comparing Drain Types After Minimally Invasive Esophageal Cancer Surgery
This study compares two different ways of placing drains after minimally invasive surgery for esophageal cancer. It aims to find which method helps you recover better and with fewer complications.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07005973Recruiting
Mindfulness app for surgery anxiety
This trial tests if a mobile mindfulness program can help reduce anxiety before surgery. If you feel anxious about an upcoming non-emergency surgery under general anesthesia, you may be able to join.
Hong KongAges 18 years+ - NCT07006610Recruiting
Tape or cooling therapy for jaw surgery recovery
This study tests whether cooling with a hilotherapy device or taping with kinesio tape helps reduce swelling and pain after double-jaw surgery. Results may lead to a gentler recovery for you.
Istanbul, BağcılarAges 18–50 - NCT07006675RecruitingPhase 3
NSAIDs for Tibia Fracture Pain and Healing Study
This study tests whether NSAID pain relievers (like ibuprofen) affect bone healing after a broken tibia and if they can help reduce the need for stronger painkillers. If you qualify, you could help doctors learn the safest way to manage pain after this common injury.
Indianapolis, IndianaAges 18–80 - NCT07008092Recruiting
Using PGE-M to predict appendicitis in children
This trial checks if a substance called PGE-M found in urine can help predict acute appendicitis in children with belly pain. If it works, it could help doctors diagnose appendicitis faster and without needing a blood test or CT scan.
SplitAges 5–17 - NCT07008105Recruiting
One session therapy for chronic pain
This study tests whether a single 90-minute online session can help people with chronic pain feel better. If you live with ongoing pain and want to try a brief psychological approach without medication, you may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT07008261Recruiting
Robot-assisted bladder removal surgery study
This study is for people who are scheduled to have their bladder removed (radical cystectomy). It looks at whether using a robot helps with blood loss, pain, and the need for blood transfusions during and after surgery.
Frankfurt am MainAges 18 years+ - NCT07008391Recruiting
High-sensitivity troponin test in ambulance care
This trial tests whether using a high-sensitivity troponin I test in the ambulance, along with standard care, can help emergency medical services better identify heart attacks. This might lead to faster treatment for patients with chest pain or suspected heart attack.
Stockholm, ÅrstaAges 18 years+ - NCT07008703RecruitingPhase 1/Phase 2
Study of sss40 for cancer bone pain
This trial tests a new injection called sss40 to treat moderate-to-severe pain caused by cancer that has spread to the bones. The goal is to see if it is safe and effective for people whose pain is not being controlled by current treatments.
Zhengzhou, HenanAges 18 years+ - NCT07009028Recruiting
Storigami to reduce pain and fear from IV insertion in kids
This study tests a fun storytelling-and-paper-folding method called 'storigami' to see if it helps children feel less pain, fear, and worry when they get an IV. It's for children who need an IV for the first time during this hospital visit.
Izmir, BornovaAges 6–9 - NCT07009951Recruiting
Virtual reality during heart device implant
This trial tests if using a virtual reality (VR) headset during pacemaker or defibrillator implant surgery can help reduce pain and anxiety. It may offer a drug-free way to help you feel more comfortable during the procedure.
CosenzaAges 18 years+ - NCT07010029Recruiting
Heart vein device for angina with no blocked arteries
This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.
WarsawAges 18 years+ - NCT07012278Recruiting
St. John's Wort oil for c-section recovery
This study tests if St. John's Wort oil helps heal the wound and reduce pain after a first cesarean section. If you've just had your first c-section and speak Turkish, this trial might be for you.
SakaryaAges 18–45
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.