Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06982989Recruiting
Wearable light therapy for pelvic pain
This study tests a wearable device that uses LED light to treat pelvic pain. It may be an option for people who want a non-medicine approach to managing their pain.
Beijing, Beijing MunicipalityAges 18–35 - NCT06983678Recruiting
Quitting smoking and pain sensitivity study
This study looks at how quitting smoking affects pain sensitivity in people who smoke, especially those with chronic low back pain. Researchers will use brain scans and daily surveys to understand these changes.
Durham, North CarolinaAges 21–65 - NCT06984354Recruiting
Digital treatments for chronic low back pain
This trial tests a smartphone app to help people with long-term low back pain. It aims to see if digital treatments can reduce pain and improve daily function.
Randwick, New South WalesAges 18 years+ - NCT06984939Recruiting
Handheld distraction tool for kids during needle procedures
This study tests a small handheld tool that may help distract children and teenagers during painful procedures like getting an IV, a blood draw, a dental needle, or if you have just been diagnosed with type 1 diabetes and need frequent blood checks and insulin shots. The tool is meant to make the experience less stressful.
Bergen, VestlandAges 8–15 - NCT06984952Recruiting
ERAS program for recovery after minimally invasive stomach cancer surgery
This study tests whether a special care program called ERAS (Enhanced Recovery After Surgery) helps people recover better and faster after keyhole surgery for stomach cancer. It aims to improve your hospital experience and reduce complications.
BusanAges 19 years+ - NCT06985849Recruiting
Gentle exercise for chronic low back pain
This study compares two gentle exercise programs (Feldenkrais and Otago) to see which one helps people with chronic low back pain and balance problems feel better and move more easily. It focuses on adults who have had pain for at least 3 months and have some trouble with balance.
LahoreAges 18–65 - NCT06986694Recruiting
Voodoo flossing for knee arthritis pain and mobility
This study tests if a special flossing technique (tight elastic bands wrapped around the knee) can improve pain, stiffness, and walking in people with knee osteoarthritis. It is designed for patients who have had knee pain for at least 3 months and have trouble walking or balancing.
Lahore, Punjab ProvinceAges 45–65 - NCT06986707Recruiting
Hands-on therapy for low back pain from muscle knots
This study compares two gentle hands-on techniques to relieve low back pain caused by muscle knots in the quadratus lumborum (a deep lower back muscle). It may help if you have had back pain for at least 3 months and find it hard to move certain parts of your lower back.
Lahore, Punjab ProvinceAges 20–45 - NCT06987175Recruiting
Sedante Neo therapy for low back pain
This study tests a therapy called Sedante Neo to see if it reduces pain, improves movement, and boosts quality of life in people with common low back pain. It is designed for adults aged 20–40 whose back pain is mild to moderate and affects daily life.
Lahore, Punjab ProvinceAges 5 months–9 months - NCT06991075Recruiting
TENS for pain relief during IUD placement
This study tests if a small device called TENS (which uses mild electrical pulses) can reduce pain when getting an IUD placed. If you are coming to MUSC Women's Health for an IUD insertion and choose a specific type, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06991205Recruiting
Web mind-body program for pain and substance use
This trial tests a web-based mind-body program to help people who have ongoing arm or hand pain and also use substances like alcohol or cannabis. It aims to improve resilience and reduce pain without requiring in-person visits.
Boston, MassachusettsAges 18 years+ - NCT06991231Recruiting
Cryoablation benefits in knee replacement surgery
This trial tests if a special cold treatment (cryoablation) can help reduce pain or improve recovery for people getting knee replacement surgery for arthritis. It might offer an extra option to feel better after the procedure.
New York, New YorkAges 18 years+ - NCT06991387Recruiting
Myofascial release for text neck pain
This study tests a hands-on therapy called myofascial release to see if it can quickly ease neck pain and related symptoms from 'text neck' (pain from using devices too much). If you are a young adult who spends a lot of time on your phone and has neck pain, you might be a good fit.
Karabük, Karabük ProvinceAges 18–40 - NCT06992895Recruiting
Hologram for pain and fear during burn dressing changes in children
This trial tests whether watching a hologram during burn dressing changes can reduce pain, anxiety, and fear in children. It may help make the experience less stressful for kids aged 3 to 12 with small, second-degree burns.
Erzurum, YakutiyeAges 3–12 - NCT06993922Recruiting
Scalp block with added sedative for brain surgery pain
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
CairoAges 18–65 - NCT06994559Recruiting
Music with ketamine for chronic pain
This study tests if listening to music during ketamine infusions helps reduce chronic pain better than ketamine alone. It is for people already getting ketamine infusions for non-cancer pain.
Montreal, QuebecAges 18 years+ - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT06995248Recruiting
Laughter yoga for cancer patients and caregivers
This trial explores whether laughter yoga can help reduce pain and fatigue and improve overall well-being for people with cancer and the people who care for them.
AnkaraAges 18–65 - NCT06995534Recruiting
Splint or Exercise for De Quervain's Wrist Pain
This trial compares wearing a splint versus doing specific exercises to treat De Quervain's tenosynovitis, a condition that causes wrist pain and swelling. It may help if you have new or worsening wrist pain without other injuries or diseases.
KonyaAges 18–65 - NCT06996015Recruiting
SNAGs and CBT for neck pain relief
This study tests whether combining two hands-on techniques (SNAGs and CBT) can reduce neck pain, improve head posture, and help you move better. It's for people with moderate neck pain that hasn't been treated recently.
Faisalabad, Punjab ProvinceAges 18–28 - NCT06996340Recruiting
White noise during IVF treatment for women with infertility
This study tests whether listening to white noise can help reduce stress in women undergoing in vitro fertilization (IVF) for the first time. It may help you feel more relaxed during treatment.
Samsun, AtakumAges 18–35 - NCT06996561RecruitingPhase 2/Phase 3
How your genes affect pain relief after surgery
This study looks at how your genes might affect pain relief from a medication called nalbuphine after abdominal or pelvic surgery. It aims to personalize pain management based on your genetic makeup.
Karachi, SindhAges 18–70 - NCT06996574Recruiting
Comparing an all-in-one procedure with at-home screening for chronic pain
This trial tests if a single, all-in-one procedure works as well as the usual two-step process (screening at home first) for people with long-term nerve pain. It looks at how well pain is controlled and whether the simpler approach saves money.
AmsterdamAges 18 years+ - NCT06996639Recruiting
Can eating before cardiac catheterization help? Study for heart patients
This study looks at whether it's safe to let patients eat a light meal before a scheduled heart catheterization, instead of fasting. It aims to improve comfort and experience for people with stable chest pain or certain types of heart attacks.
Tampa, FloridaAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.