Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70 - NCT06829030Enrolling by invitationPhase 1/Phase 2
Comparing two injections for low back pain relief
This trial compares two types of injections—one standard anti-inflammatory drug and one simple sugar water solution—to see which works better for treating low back pain in an emergency setting. If you are an adult between 18 and 55 with isolated low back pain, this study may help find a more effective pain treatment.
AksarayAges 18–55 - NCT06822764Enrolling by invitation
Thinking about pain intensity
This study looks at how people think about and rate their own pain. You may be able to join if you have had muscle or bone pain for at least 3 months, in more than one area, and that pain varies in intensity.
Columbia, MissouriAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT06808620Enrolling by invitation
Peanut balls for labor support
This study tests if using a peanut-shaped ball during birth helps women in labor. It may make the process more comfortable and support a natural vaginal delivery.
ErzurumAges 18–45 - NCT06808386Enrolling by invitation
How often should you train for knee pain relief?
This study looks at how different training frequencies affect knee pain recovery. It may help active adults who have had front knee pain for at least three months.
São Paulo, São PauloAges 18–40 - NCT06808321Enrolling by invitation
Benidipine for high blood pressure or chest pain
This study looks at how well Benidipine works for people with high blood pressure or stable chest pain from heart disease. If you are already taking Benidipine for at least a month, this trial may help doctors learn more about its benefits.
AntalyaAges 18–80 - NCT06807229Enrolling by invitation
Core exercises vs. standard therapy for period-related back pain
This study compares core-strengthening exercises with standard physical therapy to see which works better for easing low back pain during your period. If you have painful cramps that affect your lower back, this trial may help find a treatment that works for you.
Gamasah, Al ManşūrahAges 18–35 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06800859Enrolling by invitation
Predicting headache after spinal puncture
This study looks at patients having spinal anesthesia to find patterns that might predict a post-dural puncture headache. It aims to create a risk model that can help prevent or manage this complication.
Wuhan, HubeiAges 3–34 - NCT06800846Enrolling by invitationPhase 4
Pain relief after knee replacement: injection methods compared
This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.
Khlong Luang, Changwat Pathum ThaniAges 50–80 - NCT06798493Enrolling by invitation
CRPS and chronic pain measurement study
This study is testing a new way to measure CRPS symptoms and other chronic pain in one arm or leg. It aims to help doctors better understand and treat your condition.
New York, New YorkAges 18 years+ - NCT06793293Enrolling by invitation
Laser therapy for c-section incision pain
This trial tests if a high-level laser can reduce pain and help healing after a cesarean section. If you've had a C-section and have incision pain, this treatment may offer relief without medication.
CairoAges 20–40 - NCT06785766Enrolling by invitation
Yoga for PMS: Balance, focus, and body awareness
This trial tests whether yoga can help with PMS symptoms like poor balance, brain fog, and posture. It looks at how yoga might improve your body awareness and overall well-being during your menstrual cycle.
Siirt, Si̇i̇rtAges 18 years+ - NCT06785363Enrolling by invitation
Pelvic ligament release for postpartum back pain
This study tests a technique to release a tight pelvic ligament that can cause lower back pain after pregnancy. It may help women who recently gave birth and have mechanical back or pelvic pain.
CairoAges 25–30 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06777862Enrolling by invitation
Neck pain study for long-term relief
This study tests if a new approach can help people with chronic neck pain that has lasted at least 6 months and hasn't been treated in the past year. It aims to improve quality of life by finding better ways to manage pain.
Kırşehir, MerkezAges 18–65 - NCT06777381Enrolling by invitation
Pain after root canal treatment in lower molars
This study compares how much pain people feel after a single root canal treatment on a lower back molar. It may help find a way to reduce discomfort after the procedure.
CairoAges 25–45 - NCT06758973Enrolling by invitation
Turkish pain anxiety scale study
This study is testing a short Turkish questionnaire about how pain affects your emotions. If you have chronic pain (lasting at least 3 months) that happens 4 or more days a week and is at least a 3 out of 10 in intensity, you may be able to help.
Kırşehir, MerkezAges 18–65 - NCT06754111Enrolling by invitation
Can the birth environment help with pain and fear?
This study looks at how the birth environment (like a calm, comfortable room) affects pain, fear, how you give birth (vaginal or C-section), and how long labor lasts. It's for first-time mothers who are healthy and not high-risk.
Burdur, BucakAges 18–35 - NCT06749509Enrolling by invitation
Musculoskeletal rehab courses and work ability study
This study looks at whether face-to-face or online rehabilitation courses help people with musculoskeletal disorders stay at work or return to work. It compares these courses to standard care.
HelsinkiAges 18 years+ - NCT06739460Enrolling by invitation
Comparing pain relief: ketamine vs magnesium for hysteroscopy
This study compares two different sedatives, ketamine and magnesium, to see which provides better pain relief for women having a hysteroscopy (a procedure to examine the uterus). It might help you if you are having this procedure and want to be more comfortable during sedation.
Ankara, YenimahalleAges 18–55 - NCT06726018Enrolling by invitation
Brain stimulation and pain conditioning in healthy adults
This study explores how the brain processes pain by using gentle magnetic pulses (TMS) and repeated cold or pressure stimuli. It is for healthy people who are pain-free and aims to understand pain control better.
El Paso, TexasAges 18–75 - NCT06721000Enrolling by invitation
Patient-controlled vs. standard epidural pain relief
This trial compares two types of epidural pain management during surgery. It tests whether letting you control your pain medication yourself works better than the standard method.
Karachi, SindhAges 19 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.