Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT05654168Enrolling by invitation
Ultrasound study of muscle changes in professional dancers
This study uses ultrasound to look at how dancers’ muscles look and develop over time. It may help researchers understand muscle health and patterns in professional dancers.
Madrid, MadridAges 18 years+ - NCT05636137Enrolling by invitation
Study links internet habits with pain and body awareness
This study asks high school students about internet use, musculoskeletal pain (pain in muscles and bones), and body awareness (how well you notice your body). It aims to understand whether these things are connected and may help guide future supports for teens.
Muğla, MenteşeAges 15–18 - NCT05513417Enrolling by invitation
Digital pelvic health program for women with pelvic pain
This study tests a digital (phone/app-based) program to help women with pelvic pain or pelvic health symptoms. It may help by guiding pelvic-focused exercises and care, especially if you’re recovering from pelvic surgery or managing ongoing symptoms.
Draper, UtahAges 18–99 - NCT05477004Enrolling by invitation
Study of ketamine infusions for ongoing chronic pain
This study is observing people with chronic pain who are getting ketamine infusions at Stanford. You may help by completing email surveys about how you feel, which can help the team understand the treatment’s impact.
Stanford, CaliforniaAges 18 years+ - NCT05474274Enrolling by invitation
Home pain app that teaches treatment after outpatient plastic surgery
This trial tests a home-based “pain coaching” system (using a phone app and a TENS device) to help people manage pain after lower-risk outpatient plastic surgery. It may help you feel more in control of pain at home using guided exercises and device-based pain relief.
Jacksonville, FloridaAges 18 years+ - NCT05315596Enrolling by invitation
Tracking pain and recovery answers after surgery
This study checks how patients report pain and recovery over time after surgery. It may help improve how hospitals understand and manage pain after operations.
JenaAges 18 years+ - NCT05266339Enrolling by invitation
Testing mirror training after rotator cuff repair
This trial looks at whether mirror-based arm exercises (“cross-education”) help recovery after arthroscopic rotator cuff surgery. It may help improve shoulder movement and function by training the other arm to support rehab.
Istanbul, BakırkoyAges 35–65 - NCT05247255Enrolling by invitationEarly Phase 1
Nerve block during hip replacement surgery
This early-stage study tests whether a specific nerve block to numb the lower back area can make total hip replacement surgery more comfortable. It looks at patients who are having planned (elective) hip replacement and whether the nerve block is safe and works well.
Santa Monica, CaliforniaAges 18 years+ - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT05183503Enrolling by invitation
Study of pain, stress, anxiety, and depression in jaw disorder
This study looks at how chronic jaw pain from temporomandibular disorder (TMD) relates to stress, anxiety, and depression in adults. Your results may help researchers better understand what affects symptoms and how people respond to care.
WroclawAges 18–80 - NCT05116722Enrolling by invitation
Shoulder pacemaker for abnormal shoulder blade movement
This study looks at a special “pacemaker” device to help with scapular dyskinesis (abnormal movement of the shoulder blade) and posterior shoulder instability (the shoulder tending to slip backward). It may help people who have these movement and stability problems but not certain other shoulder conditions.
Salt Lake City, UtahAges 18–80 - NCT05115461Enrolling by invitation
Study pain and balance in lumbar disc nerve pain
This trial studies how nerve pain from a slipped/herniated low-back disc affects postural (balance) stability. It may help researchers understand better ways to support balance and reduce nerve-related pain symptoms.
IzmirAges 18–60 - NCT05064891Enrolling by invitation
Ultrasound therapy for shoulder movement after stroke
This trial studies whether using ultrasound on a shoulder nerve (the suprascapular nerve) and guided shoulder movement exercises can improve shoulder motion in people after a stroke. It may help if your biggest problem is pain and limited shoulder movement after stroke.
TaipeiAges 20–80 - NCT04251429Enrolling by invitation
Healthy workplace program for public healthcare workers
This trial studies a workplace program delivered by trained peers to improve health in public-sector healthcare facilities. You may be able to join if you are a direct employee of the agency that runs the facility.
Ages 18 years+ - NCT04008173Enrolling by invitation
Survey study of acute heart attack symptoms
This study collects information about symptoms and experiences during acute coronary syndromes, which are sudden, serious heart events like heart attacks or unstable angina. It may help researchers understand patterns of care and symptoms to improve future treatment and support.
Bologna, BolognaAges 18 years+ - NCT04003311Enrolling by invitation
Follow-up for specific shoulder implant types and surgery
This study checks outcomes in people who already received certain Zimmer Biomet shoulder implant components using the correct surgical technique. It may help improve how these specific implants are used and monitored after surgery.
Boise, IdahoAges 18 years+ - NCT04003272Enrolling by invitation
Reverse shoulder implant study for severely damaged rotator cuff
This trial studies a specialized reverse shoulder implant system for people whose rotator cuff is badly damaged or who had a prior shoulder replacement that failed. It aims to reduce pain and improve function by improving how your shoulder works, especially when the rotator cuff can’t do its job.
Louisville, KentuckyAges 18 years+ - NCT03674255Enrolling by invitation
Tests how accurate heart ultrasound is during stress
This study checks how well a heart ultrasound (echocardiography) works when your heart is at rest and under stress. You may benefit by getting closer attention to how the test is done, especially if it’s being used to look for blocked-heart-blood-flow problems.
Ages 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.