Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT06243718Recruiting
Surgery for paralyzed diaphragm nerve
This trial looks at how patients feel and recover after surgery to fix the nerve that controls the diaphragm. It aims to learn about people's experiences to improve care for diaphragmatic paralysis.
Red Bank, New JerseyAges 18–70 - NCT01344200RecruitingPhase 2
Celecoxib drug study in children on leukemia treatment
This trial studies how celecoxib moves through a child’s body and how much reaches the fluid around the brain and spinal cord. It’s for children (age 2–12) who are in the maintenance phase of certain blood cancers, to better understand dosing and safety.
Ottawa, OntarioAges 2–12 - NCT07866040Recruiting
Biofeedback exercises versus Mulligan method for neck pain
This trial compares two non-surgical treatments for ongoing neck pain: biofeedback exercises, which use sensors to help you learn to relax and strengthen neck muscles, and the Mulligan method, a hands-on technique that improves movement and posture. It aims to see which is better for reducing pain, improving mobility, and correcting posture in women.
Badr, Cairo GovernorateAges 18–45 - NCT05424198Recruiting
A new device for neck pain treatment compared to the standard one
This study tests a new device that uses heat to treat neck pain that has lasted at least 3 months. It compares the new device to the standard one to see if it works better or is safer.
Farmington, UtahAges 18 years+ - NCT07856498Recruiting
Understanding pain and movement in postmenopausal women with low back pain
This study looks at how thoughts and fears about pain affect physical activity in women after menopause who have chronic low back pain. The goal is to learn more about these connections to help improve future treatments.
Istanbul, IstanbulAges 45–65 - NCT07868315Recruiting
Single-visit root canal pain and success comparison
This study compares pain after a single-visit root canal treatment using different sealers (materials used to fill the root canal) in asymptomatic (pain-free) teeth. It aims to find which sealer causes less discomfort and has a better success rate.
Istanbul, EsenlerAges 18–65 - NCT07855549Enrolling by invitation
Nerve blocks for pain relief after chest surgery
This study compares two types of nerve blocks (numbing injections) to see which one works better for pain relief after chest surgery. The goal is to help you feel more comfortable and use less pain medicine after your operation.
Minya, Minya GovernorateAges 18–70 - NCT07860476Recruiting
Osteopathy and hypnosis for cancer pain
This study tests whether combining osteopathy with hypnosis can help reduce chronic pain and emotional distress in cancer patients. If you have had pain for 3 months or more and are feeling emotionally affected by it, this treatment might offer additional relief.
Levallois-Perret, Île-de-France RegionAges 18 years+ - NCT07855445Recruiting
Nerve pain and MRI findings in lumbar spinal stenosis
This study looks at how nerve pain relates to MRI results in people with lumbar spinal stenosis, a condition where the spinal canal narrows and presses on nerves. It aims to better understand the link between symptoms and imaging, which could help improve care.
Istanbul, IstanbulAges 18 years+ - NCT06270121Recruiting
Mobile health app for healthy aging at home
This study is testing a mobile health app designed to help seniors live independently at home. If you join, you will use the app and answer surveys to see if it supports healthy aging.
SeoulAges 65 years+ - NCT06217029Recruiting
MRI Study of Neck Pain in Adults
This study uses MRI scans to look at how neck pain affects young and middle-aged adults. It helps doctors understand the condition better and may guide future treatments.
Xi'an, ShaanxiAges 18–50 - NCT07854028Recruiting
Muscle release techniques for low back pain
This study tests two hands-on treatments—strain counter strain and muscle energy technique—to ease low back pain and improve movement. It may help if you have had low back pain for 3–6 months and have specific tender spots in your back muscles.
Lahore, Punjab ProvinceAges 20–40 - NCT07855380Recruiting
Ultrasound-guided pain block for chronic pain after cancer surgery
This study tests a pain-relieving injection placed near the belly muscles using ultrasound guidance, to see if it helps reduce long-term pain after abdominal surgery for cancer. It may offer a new way to manage pain without strong painkillers.
CairoAges 18–65 - NCT07861906Recruiting
Wearable device for jaw muscle pain
This study tests a 24-hour wearable device that tracks jaw muscle activity to better understand and manage chronic jaw muscle pain. You would wear the device for a day to see how your muscles behave, which could help improve future treatments.
Downers Grove, IllinoisAges 18 years+ - NCT05325580RecruitingPhase 3
IV magnesium vs placebo for sudden non-injury headaches
This trial tests whether giving magnesium sulfate through a vein in the emergency room can reduce sudden (non-injury) acute headaches compared with a placebo. It may help people whose headache comes on suddenly and is not caused by an injury.
MonastirAges 18–85 - NCT07860983Enrolling by invitation
Morning exercise program for school children
This study tests a 16-week morning exercise program at school to see how it affects children's physical health and emotional well-being. If your child enjoys being active, this program could help them feel better both physically and mentally.
Istanbul, KartalAges 6–12 - NCT07867951Recruiting
Pain after two root canal medicines
This study compares two medicines placed inside a tooth during root canal treatment to see which one reduces pain better afterward. It may help people with an infected tooth causing pain.
Swāt, KpkAges 16–50 - NCT07853664RecruitingPhase 2/Phase 3
Dexamethasone and diclofenac gel for facial surgery pain
This study tests a gel containing two pain and swelling medicines applied to the skin after facial surgery or facial injury repair. The goal is to see if it provides better pain relief and less swelling than usual care.
DhamarAges Any age - NCT06288165Recruiting
Sinus reducer trial for persistent chest pain
This study tests a device called the sinus reducer for people with long-lasting chest pain that hasn't improved with medication or other procedures. It may help if you have limited options for treatment.
Lubin, Lower Silesian VoivodeshipAges 18 years+ - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT06279663Recruiting
Comparing bypass surgery vs stenting for high-risk heart attacks
This study compares two common treatments (bypass surgery vs. stenting) for people having a high-risk heart attack that involves blockages in multiple arteries. It aims to find which approach leads to better long-term outcomes.
Novosibirsk, Novosibirsk OblAges 18 years+ - NCT06336447Recruiting
Virtual reality and nerve block for chronic knee pain
This study tests whether using virtual reality (VR) before a standard heat-based nerve block (radiofrequency ablation) can improve relief of long-term knee pain caused by arthritis. If you qualify, you'll receive the RFA procedure and may be randomly assigned to also use VR.
Chicago, IllinoisAges 18 years+ - NCT05923736Recruiting
Study of cardiovascular risk in people with digital osteoarthritis
This study looks at how heart-and-blood-vessel risk differs in people with digital osteoarthritis (arthritis affecting the fingers). It may help doctors understand whether finger osteoarthritis is linked with higher cardiovascular risk.
Clermont-FerrandAges 18 years+ - NCT06211231Recruiting
Mindfulness & yoga self-management program for endometriosis
This study tests a digital mindfulness and yoga program designed to help people with endometriosis manage symptoms like pelvic pain and fatigue. You would practice at home for about 30-45 minutes almost every day over the treatment period.
Aarhus, Central JutlandAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.