Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07767344Recruiting
Video education for gallbladder surgery recovery
This trial tests whether watching an educational video before gallbladder removal surgery can improve trust in your doctor, reduce pain, and lower anxiety. It may help you feel more prepared and calm before and after your procedure.
Sanliurfa, EyyübiyeAges 18–65 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT04206215Recruiting
Noninvasive brain stimulation for carpal tunnel pain relief
This study tests whether a noninvasive brain stimulation treatment can reduce chronic carpal tunnel (CTS) pain, especially when pain spreads beyond the usual nerve area. If you have long-lasting CTS pain that hasn’t improved with standard treatments, you may be able to try this therapy while being closely monitored for safety.
Charlestown, MassachusettsAges 18–80 - NCT07771816Enrolling by invitation
Mouth rinse and cold therapy for lower molar pain
This study tests whether using different strengths of a disinfectant rinse inside the tooth, sometimes combined with cold therapy, can reduce pain after a type of root canal treatment for lower molars. It aims to find the most comfortable and effective approach for managing post-procedure pain.
Cairo, Cairo GovernorateAges 15–40 - NCT07770139Enrolling by invitation
Online yoga and breathing for student stress relief
This study compares two online programs—one with yoga poses and breathing, the other adding a special breathing technique—to see if they help reduce stress and improve well-being in university students.
IstanbulAges 18–30 - NCT07689162RecruitingPhase 2
Long-acting vs standard numbing for nose surgery pain
This study compares two types of numbing medicine used during open rhinoplasty (nose surgery) to see which one controls pain better after surgery. One is a long-acting version (liposomal bupivacaine) and the other is the standard numbing medicine (bupivacaine).
St Louis, MissouriAges 18 years+ - NCT07586189Recruiting
Comparing two anesthesia methods for spine surgery
This study compares two different ways doctors can put patients to sleep for spine surgery and measures how the patient's heart and blood pressure respond. The goal is to see which method is safer and more stable during surgery.
IstanbulAges 18 years+ - NCT07760103Recruiting
Core exercises for lower back pain in recreational athletes
This trial compares two sets of core-strengthening exercises to see which works better for athletes with recurring lower back pain. It may help you find a routine that reduces pain and lets you keep being active.
IstanbulAges 18–45 - NCT07369726Recruiting
Mobilization and caffeine after cesarean
This trial tests whether getting out of bed and drinking coffee after a planned cesarean can help reduce pain and speed up recovery. It is for women who have moderate to severe pain after surgery.
Konya, KonyaAges 18–35 - NCT07329309Recruiting
Breathing exercises for pain after cesarean
This study tests if a gentle breathing technique called Pranayama can help reduce pain after a planned cesarean. It compares the breathing exercise to usual care to see if it improves recovery.
Konya, KonyaAges 18–35 - NCT07769385Enrolling by invitation
Robotic fish and aquarium to ease pain and fear in children
This trial tests whether using a robotic fish or watching an aquarium can help reduce pain, fear, and anxiety in children during medical procedures. It might make the experience more comfortable for your child.
Bingoel, TurkeyAges 5–10 - NCT07489573RecruitingPhase 4
Study of secukinumab for Chinese adults with moderate-to-severe HS
This study tests if a drug called secukinumab (a self-injected biologic) is safe and effective for adults with moderate-to-severe hidradenitis suppurativa (HS) in China. It may help reduce the number of painful HS lesions.
Guangzhou, GuangdongAges 18 years+ - NCT06206486Recruiting
Gut germs and pain after kidney transplant
This study looks at whether the germs in your gut (microbiome) and certain chemicals in your blood affect pain after a kidney transplant. By joining, you may help doctors better understand and manage pain for future kidney transplant patients.
Chicago, IllinoisAges 18 years+ - NCT07149870Recruiting
Pain management team for veterans with chronic pain
This study is testing whether a team-based pain management approach helps veterans with chronic pain and long-term opioid use. It aims to improve function and safety by addressing opioid concerns.
Birmingham, AlabamaAges 18 years+ - NCT07412223RecruitingPhase 4
Tegileridine for bowel recovery after abdominal surgery
This trial tests a painkiller called Tegileridine to see if it helps your bowels work normally again after abdominal surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07740382Recruiting
Pain block comparison for recovery after liver surgery
This study compares two types of pain-relieving nerve blocks used during liver surgery to see which one helps you breathe better and recover more comfortably after the operation.
Alexandria, Sbein-ElkomAges 18–75 - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT06658821Enrolling by invitation
Study of LDL557 for knee arthritis in older adults
This trial tests whether a supplement called LDL557 can improve early-stage knee arthritis in people over 65. It aims to reduce pain and slow joint damage.
TaichungAges 45–80 - NCT07696741Recruiting
Pain Reprocessing Therapy for Chronic Lower Back Pain
This study tests a type of talk therapy called pain reprocessing therapy (PRT) for adults with chronic lower back pain. The goal is to see if PRT can help reduce pain and improve quality of life.
Toronto, OntarioAges 18–65 - NCT07222943Recruiting
Guided Imagery App for Kids with Stomach Pain
This study tests a mobile app that uses guided imagery (a relaxation technique using your imagination) to help children ages 7–12 with stomach pain disorders. The goal is to see if the app is easy to use and helpful for managing pain.
Austin, TexasAges 7–12 - NCT06910150Enrolling by invitation
Pain relief after knee surgery: electric stimulation study
This trial tests two types of mild electric stimulation (one with tiny needles, one without) applied to the thigh muscle to reduce pain in people who had ACL knee surgery in the last six weeks. The goal is to see if this can help you feel better and recover quicker.
Madrid, MadridAges 18–55 - NCT06892795Enrolling by invitation
Predicting low body temperature during surgery in children
This study aims to predict which children might get too cold during surgery under general anesthesia lasting more than 30 minutes. It's trying to create a simple checklist to help doctors keep kids warm and safe.
Harbin, HeilongjiangAges Up to 15 years - NCT06849557Recruiting
Chair exercises for frail older adults in nursing homes
This trial tests if chair-based video games (exergaming) can help improve strength and mobility in older adults who are frail or pre-frail and live in nursing homes. It is designed for people who can sit on a chair or wheelchair without help.
KowloonAges 60 years+ - NCT06777589Recruiting
Monitoring sedation depth during lower GI endoscopy
This study tests a new way to monitor how deeply sedated you are during a colonoscopy or similar procedure. It uses a special consciousness index to help the doctor give you just the right amount of sedation.
Chongqing, Chongqing MunicipalityAges 18–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.