Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT04783454Recruiting
Preventing neck and back pain in teleworkers
This study tests ways to prevent neck and back pain in people who work at a computer from home or an office. If you qualify, you may be assigned to an intervention aimed at reducing pain and improving comfort.
Ghent, East FlandersAges 18–69 - NCT05863312Recruiting
Study of outcomes after retinal detachment repair
This study looks at how well surgery works for people with a specific type of detached retina (rhegmatogenous retinal detachment). It may help improve how doctors choose and manage treatment, based on what outcomes happen after repair.
Québec, QuebecAges 18 years+ - NCT06134791Recruiting
Comparing neck test results in cervicogenic headache patients
This study compares people with cervicogenic headache (headache from neck problems) to see if a simple neck test can tell them apart. It aims to help doctors diagnose this type of headache better.
Ghent, Oost-VlaanderenAges 18 years+ - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60 - NCT05967663Recruiting
Staged vs same-day heart artery repair after a heart attack
This study compares doing all heart artery procedures right away versus doing part of them later in people who had a heart attack and have blockage in more than one artery. It aims to see which approach is safer and works better after the initial emergency procedure.
ShanghaiAges 18 years+ - NCT06094660Recruiting
Nerve blocking for knee arthritis pain
This study tests two treatments for knee arthritis pain when knee replacement isn't an option: a nerve block using heat (radiofrequency ablation) or a chemical injection (phenol), compared to standard care. It aims to find a better way to reduce pain and improve daily function.
Hoorn, North HollandAges 35–90 - NCT06182943Recruiting
Electroacupuncture for recent mild to moderate ankle sprains
This study tests whether a type of acupuncture with mild electrical current (electroacupuncture) can help heal a fresh, mild-to-moderate ankle sprain. You may be eligible if you sprained your ankle within the last 48 hours, have no broken bones, and do not have serious health issues.
Hangzhou, ZhejiangAges 18–60 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT07854119Recruiting
Exercise with and without hands-on therapy for upper crossed syndrome
This trial compares two types of physical therapy—one using exercises alone and the other adding a hands-on technique called positional release—to see which better relieves neck pain and improves posture in people with upper crossed syndrome.
Lahore, Punjab ProvinceAges 20–40 - NCT07867808Enrolling by invitation
Magnetic therapy versus water therapy for chronic pelvic pain
This study compares two non-drug treatments—pulsed electromagnetic therapy and hydrotherapy (warm water therapy)—to see which one better relieves long-term pelvic pain in men. If you have chronic pelvic pain from non-bacterial prostatitis, this trial could help you find a new way to manage your symptoms.
AmmanAges 42–52 - NCT07863232Recruiting
Melatonin and nutrition for fibromyalgia pain relief
This study tests whether taking melatonin, a sleep and pain hormone, along with special nutrition supplements, can help reduce fibromyalgia pain. It may offer a new way to manage symptoms.
LarissaAges 18 years+ - NCT07872215Recruiting
AI-assisted teaching before stitches for minor cuts
This study tests whether using artificial intelligence to explain stitches before the procedure helps patients feel more informed and at ease. It is for adults with minor cuts that can be closed with stitches in the emergency room.
AnkaraAges 18 years+ - NCT02346396Recruiting
At-home brain stimulation trial for long-lasting nerve pain
This study tests a device that delivers mild electrical stimulation to the brain from home to help reduce chronic nerve pain. It focuses on people whose pain has not improved enough despite stable pain medicines.
BronAges 18–80 - NCT04853732Recruiting
Pain research registry for chronic low back pain
This study is a research registry that collects information from people with chronic low back pain (and some people without chronic pain). It may help researchers better understand pain patterns and guide future treatments.
Fort Worth, TexasAges 21–79 - NCT07864025Recruiting
Better imaging for heart artery blockages in stable angina
This study uses advanced imaging techniques to look at the build-up inside heart arteries in people with stable angina. It aims to help doctors understand and treat these blockages more accurately.
LondonAges 18–79 - NCT07868484Recruiting
Pain relief after chest surgery: comparing two numbing injections
This study tests two different numbing injections given before chest surgery to see which one controls pain better and improves recovery. It may help reduce discomfort after the procedure.
Denpasar, BaliAges 18–65 - NCT07857499Recruiting
Nerve stimulation plus exercise for lipedema leg pain
This trial tests whether a gentle nerve stimulation device worn on the ear, combined with exercise, can reduce leg pain and swelling in women with lipedema. It aims to improve how well standard rehabilitation works for this condition.
Istanbul, EyupsultanAges 18–65 - NCT07864896RecruitingPhase 3
Study of a new pain medicine after knee replacement surgery
This trial tests a new oral pain medicine called suzetrigine for people who have a knee replacement. It aims to see if it helps control pain after surgery better or with fewer side effects than usual care.
New York, New YorkAges 18–80 - NCT06767566RecruitingPhase 1
Ketamine for depression and pain after cesarean delivery
This study tests whether ketamine, a medicine given during cesarean delivery, can help prevent or reduce postpartum depression and pain. It aims to find the best dose for new mothers.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06205355Recruiting
Pain measurement tool for jaw surgery patients
This study tests a device that measures your body's response to pain during jaw surgery. It may help doctors better manage your pain during and after the procedure.
SeoulAges 18 years+ - NCT05726331Recruiting
Tai chi and chiropractic for long-term neck pain
This trial looks at whether a program of tai chi and chiropractic care can improve chronic, non-specific neck pain and daily function. It may help people who have had neck pain for months and want a structured exercise-and-care approach.
Chestnut Hill, MassachusettsAges 18–65 - NCT07866885Recruiting
Spinal vs general anesthesia for laparoscopic hernia repair
This study compares two ways to manage pain during laparoscopic inguinal hernia surgery: spinal anesthesia (numbing the lower body) versus general anesthesia plus a nerve block (TAP block). The goal is to see which approach provides better pain control and recovery.
Istanbul, IstanbulAges 18–65 - NCT06232473RecruitingPhase 4
Education and duloxetine for multisystem functional somatic disorder
This trial tests whether a combination of patient education and the medication duloxetine can help people with a condition that causes multiple unexplained physical symptoms (functional somatic disorder). It aims to see if using both treatments together works better than either alone.
AarhusAges 18–60 - NCT06237075Recruiting
Brain imaging and mild stimulation for nerve pain
This study uses brain imaging (fMRI) and a mild electrical stimulation (tDCS) to understand and potentially help nerve pain. You may be eligible if you have nerve pain or numbness from peripheral neuropathy or a stroke, and can avoid caffeine/alcohol before visits.
TaipeiAges 20–90
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.