Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,753 recruiting studies in this area right now.
By phase
- Not applicable3,099
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University30
- Mayo Clinic27
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York81
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,752 total
- NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75 - NCT06283199Recruiting
Tracking pain reports with a smartphone app
This trial compares pain reports recorded in real time using a smartphone app to those collected during monthly clinic visits. It aims to understand if daily tracking gives a more accurate picture of symptoms for people with musculoskeletal conditions.
BolognaAges 18 years+ - NCT06283862Recruiting
Virtual cannabis coaching for veterans with chronic pain
This study tests a virtual program to help veterans with chronic pain who are using (or planning to use) CBD or cannabis. You'll join educational sessions and track your symptoms and cannabis use on your smartphone.
Ann Arbor, MichiganAges 18 years+ - NCT06284473RecruitingPhase 4
Ketamine with numbing medicine for minor emergency procedures
This study tests whether adding ketamine to the usual numbing medicine makes minor procedures in the emergency department less painful. You may be a good fit if you are having a small procedure like stitches or abscess drainage.
Maywood, IllinoisAges 7–70 - NCT06288165Recruiting
Sinus reducer trial for persistent chest pain
This study tests a device called the sinus reducer for people with long-lasting chest pain that hasn't improved with medication or other procedures. It may help if you have limited options for treatment.
Lubin, Lower Silesian VoivodeshipAges 18 years+ - NCT06290063RecruitingPhase 2
CBD for older adults who use cannabis
This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.
Boulder, ColoradoAges 60 years+ - NCT06290024Recruiting
Nerve pain study: tracking long-term symptoms
This study follows people with nerve pain over time to learn more about their condition. You will not receive a new treatment, but your data will help doctors understand neuropathic pain better.
Shanghai, YangpuAges 18–85 - NCT06290011Recruiting
Mixed reality for chronic pain relief
This study tests a new therapy that uses mixed reality (a type of glasses that shows virtual images over the real world) to help distract you from pain and teach relaxation. It may help people with chronic pain who have not tried VR or MR before.
Shanghai, YangpuAges 18–85 - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT06291363RecruitingPhase 4
Esmolol for pain control during laparoscopic surgery
This trial tests a drug called esmolol to see if it helps control pain during and after laparoscopic surgeries that involve a small cut below the belly button. It may help people having a hysterectomy or left colon removal feel less pain during anesthesia.
Montreal East, QuebecAges 18–65 - NCT06295679Recruiting
Repatha plus standard care for heart disease in Chinese patients
This study tests whether adding Repatha (a weekly injection that lowers cholesterol) to your usual heart medications can reduce the risk of future heart attacks, strokes, or other heart problems. It is for people who have already had a heart attack or stroke, or have certain high-risk conditions.
Beijing, Beijing MunicipalityAges 18–150 - NCT06296979Recruiting
Nerve stimulation for shoulder pain from liver or gallbladder issues
This study tests if stimulating a nerve in the neck can reduce right shoulder pain caused by liver or gallbladder problems. It may offer a non-drug option for managing this type of pain.
Seville, SevillaAges 18 years+ - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT06297447Recruiting
Keeping it Simple: rehab for chronic pain
This study looks at how to better help people with ongoing muscle or joint pain who are getting rehabilitation through their local municipality. The goal is to learn what works best for you.
Holbæk, Region SjællandAges 18 years+ - NCT06299683Recruiting
Pain type and bladder pain syndrome treatment study
This study is testing if the type of pain you feel can help predict which treatments work best for interstitial cystitis (a condition that causes bladder pain and pressure). It may help match you with more effective care.
Franklin, TennesseeAges 18 years+ - NCT06303609Recruiting
Radiofrequency treatment for pelvic pain during sex
This study tests whether a special type of radiofrequency (a gentle heat treatment) can help women who have pain during vaginal penetration. You will not receive any other treatment for your pain during the study.
Salvador, Estado de BahiaAges 18–45 - NCT06306183Recruiting
Vitamin C for pain relief after an ER visit
This trial tests whether a high dose of vitamin C can help reduce pain for people who come to the emergency department with new muscle or bone pain. If you qualify, you will receive vitamin C or a placebo and track your pain over time.
Ottawa, OntarioAges 18 years+ - NCT06308029Recruiting
E-health pain self-management for breast cancer survivors
This trial tests an online program to help people manage lasting pain after breast cancer treatment. It's designed for those whose pain still gets in the way of daily life, even after finishing primary treatment.
AntwerpAges 18 years+ - NCT06310096Recruiting
Stretching for chronic low back pain
This study tests whether a special stretching technique for the connective tissue in your lower back can help reduce pain and improve function in people with chronic low back pain (pain lasting 3 months or more). You would attend physiotherapy sessions and do regular stretches.
AnkaraAges 20–60 - NCT06311461Recruiting
Acupuncture for stable chest pain
This trial tests whether acupuncture can help relieve symptoms of stable angina, a type of chest pain that happens when your heart isn't getting enough blood. If you have chest pain at least once a week and are already on heart medications, you may be able to join.
Los Angeles, CaliforniaAges 21 years+ - NCT06311240Recruiting
Chronic pain therapy in hemodialysis patients
This study looks at whether a certain kind of therapy can help people on dialysis who have chronic pain. If you have kidney failure and have been on hemodialysis for at least 3 months, you may be able to join.
Terrassa, BarcelonaAges 18 years+ - NCT06312696Recruiting
Neck movement study with spinal manipulation therapy
This study tests whether a special hands-on therapy (spinal manipulation) can help people with long-term neck pain. It will measure how the neck moves and whether the treatment improves movement and reduces pain.
Minneapolis, MinnesotaAges 18–39 - NCT06313645Recruiting
Blood vessel aging and heart attack risk study
This study looks at how blood vessel aging relates to the type of fatty buildup in your arteries that can cause heart attacks. If you've had a recent heart attack, chest pain (angina), or minor artery disease and do not have advanced heart failure, kidney failure, active cancer, or prior bypass surgery, you may be able to join.
Milan, LombardyAges 18–75 - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,753 recruiting pain medicine studies from the U.S. registry right now, out of 6,795 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.