Clinical trials
Invasive Mechanical Ventilation clinical trials
Below are recruiting invasive mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Iowa City, IowaAges 19 years+ - NCT06330610Recruiting
Intermittent tube feeding for organ failure in the ICU
This trial tests if giving tube feeding at certain times of day, instead of continuously, helps people on breathing machines recover from organ failure faster. It is for patients who need a breathing tube and are receiving medicine to support their blood pressure.
Rouen, FranceAges 18 years+ - NCT06454006Recruiting
Light therapy for patients on breathing machines
This study tests a light therapy (called PBMT-sMF) on people in the ICU who need a breathing machine. It aims to see if the treatment helps muscles and recovery.
Porto Alegre, Rio Grande do SulAges 21 years+ - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT06501118Recruiting
Oxygen levels in ICU patients on breathing machines
This study tests whether giving a little more oxygen to ICU patients on breathing machines leads to better recovery. It compares usual oxygen levels to a more liberal target to see which is safer and more effective.
Aurora, ColoradoAges 18 years+ - NCT06579157Recruiting
Using pressure-sensing mattresses to help newborns breathe on their own
This trial tests whether a special mattress that senses breathing movements can help doctors decide when to remove breathing support from newborns. It may reduce the time babies need a breathing machine.
New Taipei CityAges Up to 1 year - NCT06694740RecruitingPhase 2/Phase 3
Interferon gamma for immune recovery in the ICU
This trial tests if a drug called interferon gamma can help boost the immune system of patients in the ICU who are fighting serious infections. It is for adults who are on a breathing machine and have low immune function.
ParisAges 18 years+ - NCT06835842Recruiting
Rib mobilization for pneumonia patients on a ventilator
This study tests whether a gentle rib movement technique (called rib mobilization) can help people with pneumonia who are on a breathing machine get ready to breathe on their own. It aims to see if this therapy makes it easier to wean off the ventilator.
CairoAges 40–50 - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT06999603RecruitingPhase 2
Inhaled study drug for virus infections on ventilators
This study tests an inhaled study drug (SNG001) for adults on a breathing machine in the ICU due to a viral lung infection. The goal is to see if the drug can help patients recover faster.
Sacramento, CaliforniaAges 18 years+ - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07590362Recruiting
Testing breathing readiness measures in ventilated COPD patients
This study compares two methods of measuring whether patients with COPD who are on breathing machines are ready to breathe on their own. The goal is to find the best way to predict which patients can successfully come off the ventilator.
Sohag, Sohag GovernorateAges 18 years+ - NCT07613021Recruiting
Breathing Muscle Training to Help ICU Patients Stop Using Ventilators
This trial tests whether special breathing exercises can help patients who have been on a breathing machine (ventilator) in the ICU for at least 3 days get off the machine more successfully. The exercises focus on strengthening the muscles you use to breathe in.
ChalcisAges 18 years+ - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT07582211Recruiting
BPAP breathing support for severe asthma attacks in children
This study tests whether a special breathing mask (BPAP) can help children ages 5–17 who come to the emergency room with severe asthma attacks. The mask gently pushes air into the lungs to help them breathe more easily.
New York, New YorkAges 5–17
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Common questions
- Are there clinical trials for invasive mechanical ventilation?
- Yes. Clin2 currently lists 129 recruiting invasive mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a invasive mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a invasive mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.