Clinical trials
Invasive Mechanical Ventilation clinical trials
Below are recruiting invasive mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT07774065Recruiting
Ventilation strategies in obese patients during laparoscopic surgery
This study tests different ways of using a breathing machine (ventilator) during laparoscopic surgery in people with obesity. The goal is to find a safer and more effective ventilation method for this group.
Galveston, TexasAges 18 years+ - NCT07751237Recruiting
Ultrasound of the diaphragm during breathing machine weaning
This study uses ultrasound to look at how well your diaphragm (the main breathing muscle) is working while you are on a breathing machine. The goal is to see if this can help doctors predict when you can safely breathe on your own and leave the ventilator sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT07613021Recruiting
Breathing Muscle Training to Help ICU Patients Stop Using Ventilators
This trial tests whether special breathing exercises can help patients who have been on a breathing machine (ventilator) in the ICU for at least 3 days get off the machine more successfully. The exercises focus on strengthening the muscles you use to breathe in.
ChalcisAges 18 years+ - NCT07590362Recruiting
Testing breathing readiness measures in ventilated COPD patients
This study compares two methods of measuring whether patients with COPD who are on breathing machines are ready to breathe on their own. The goal is to find the best way to predict which patients can successfully come off the ventilator.
Sohag, Sohag GovernorateAges 18 years+ - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07233304Recruiting
Lung opening procedure safety in children on breathing machines
This trial tests a lung opening procedure (alveolar recruitment maneuver) in children on a breathing machine to see if it's safe and helpful. It compares how well the procedure works with different machine settings.
Canuelas, Buenos AiresAges 1 month–14 years - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT07199881Recruiting
Breathing effort study after major abdominal surgery
This study checks how your breathing effort changes with different levels of breathing support from the ventilator after major abdominal surgery. It helps doctors find the best settings to help you breathe comfortably while you recover.
Bangkok, BangkoknoiAges 18 years+ - NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT05207046Recruiting
Study for people on a breathing machine after spine trauma
This trial studies how care is given to people who have a traumatic injury to the spine and need a breathing machine. It may help improve treatment and recovery for people who are ventilated after injury, including those with or without spinal cord damage.
Toronto, OntarioAges 16 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years
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Common questions
- Are there clinical trials for invasive mechanical ventilation?
- Yes. Clin2 currently lists 123 recruiting invasive mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a invasive mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a invasive mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.