Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07171593Enrolling by invitation
High protein drink for Crohn's with muscle loss
This trial tests if a high protein oral nutrition drink with HMB can help people with active Crohn's disease who also have muscle loss (sarcopenia). The goal is to see if it improves muscle strength and overall health.
Guangzhou, GuangdongAges 18–50 - NCT07166328Recruiting
Body Image and Spine Curvature in Scoliosis
This study looks at how teenagers with scoliosis see their own body shape and posture. It may help doctors understand how scoliosis affects self-image and movement.
New Cairo, Cairo GovernorateAges 11–18 - NCT07171216Recruiting
Parathyroid hormone control and bone density in kidney disease
This trial tests whether regulating parathyroid hormone (PTH) can improve bone density in people with advanced chronic kidney disease (CKD) who are not on dialysis. It may help you if you have stage 4-5 CKD and high PTH levels.
Herlev, Capital RegionAges 50 years+ - NCT07164937Enrolling by invitation
Imaging and gait study for FSHD patients
This study looks at muscle MRI images and walking patterns (3D gait analysis) in people with FSHD. It helps researchers understand how the disease affects movement and muscle over time.
RomeAges 18 years+ - NCT07171008Recruiting
Ney music for comfort after lumbar disc surgery
This study tests whether listening to ney music can help reduce pain and anxiety after lumbar disc surgery. If you are eligible, you would listen to the music in the hospital, and researchers will measure how you feel.
YalovaAges 18–70 - NCT07172568Recruiting
Blood flow restriction training for tennis elbow
This study tests whether a special type of strength training that temporarily limits blood flow to the arm can help treat tennis elbow (lateral epicondylitis). It may be an option for people who have tried physical therapy without success.
Munich, BavariaAges 18–65 - NCT07174102Recruiting
Looking at lung scans in rheumatoid arthritis and related diseases
This trial studies lung scans (HRCT) from patients with rheumatoid arthritis, interstitial lung disease, or connective tissue disease to better understand lung involvement. If you have one of these conditions and have had a lung CT, you may be able to help.
PragueAges 18 years+ - NCT07171320Recruiting
Combination therapy for fibromyalgia pain
This study tests whether combining two medications, pregabalin (often used for nerve pain) and desvenlafaxine (an antidepressant that can also help with pain), is safe and effective for people with fibromyalgia who still have moderate to severe pain after trying non-drug treatments like exercise or therapy.
BeijingAges 18 years+ - NCT07166198Recruiting
Stopping age-related muscle weakness in women during inactivity
This study tests if a gentle hand exercise or a noninvasive brain stimulation can prevent muscle weakness in middle-aged women when they limit arm use for a period. It may help protect your strength and nerve function during recovery or downtime.
Manhattan, KansasAges 40–65 - NCT07166016Recruiting
Walking study for people with hammertoe and nerve damage
This study looks at how different treatments affect walking in people with hammertoe and nerve damage in their feet. It may help find better ways to improve foot function and comfort.
Harlingen, TexasAges Any age - NCT07170930Enrolling by invitation
Training program for soccer players in preseason
This trial tests a training program for soccer players during their preseason. It looks at how fitness, blood markers, and body function change. It may help soccer players improve performance and prepare for the season.
Athens, DaphniAges 18–35 - NCT07171151Recruiting
Cyst fluid study for disease markers
This trial looks at fluid from cysts to find markers that might show disease. If you have a cyst and are not pregnant or breastfeeding, you may be able to join.
SanliurfaAges 12–80 - NCT07169474Recruiting
Thumb base joint replacement for arthritis
This trial tests a surgery that replaces the joint at the base of the thumb to treat arthritis pain. It may help if you have thumb arthritis that hasn't improved with nonsurgical treatments.
MontpellierAges 18 years+ - NCT07172971RecruitingPhase 1
SGLT2i drug for heart health in Duchenne muscular dystrophy
This trial tests if an SGLT2i medication can help protect heart function in people with Duchenne muscular dystrophy (DMD). The drug is already approved for other conditions, and researchers want to see if it can slow or prevent heart muscle damage.
Nashville, TennesseeAges 8–18 - NCT07167927Recruiting
Decision support tool for children with neuromuscular scoliosis
Researchers are developing a decision support tool to help parents and doctors make decisions about surgery for children with neuromuscular scoliosis. The tool aims to provide clear information and support during the consultation.
Los Angeles, CaliforniaAges 8 years+ - NCT07170813Enrolling by invitation
Studying back braces for spine movement in healthy adults
This trial tests how different back braces affect how your spine moves. It is looking for healthy young adults to see if these braces change the way you bend or move your spine.
YalovaAges 18–35 - NCT06950463Recruiting
Circuit training for bone health after menopause
This trial tests whether a specific exercise program (circuit training) can improve bone density in women after menopause who have low bone mass. It may help strengthen bones and reduce fracture risk.
CairoAges 50–60 - NCT06950853Recruiting
Spinal surgery study using endoscopy to avoid fusion
This trial tests a less invasive spinal surgery using an endoscope (a small camera) to treat certain spine problems without fusing bones together, which may help you recover faster. It is for adults with specific types of back or leg pain from conditions like a failed previous fusion, a slipped vertebra, or a curved spine with narrowing.
BordeauxAges 18 years+ - NCT04153994Recruiting
Numbing injection study for kids’ scoliosis back surgery pain
This trial tests whether a specific numbing injection (placed in the muscles of the back) can improve pain control for children having one-stage scoliosis surgery. It may help reduce post-surgery pain needs and improve comfort.
Palo Alto, CaliforniaAges Up to 18 years - NCT06750055Recruiting
Walking assessment after lumbar spinal stenosis surgery
This study looks at how well people walk after surgery for lumbar spinal stenosis. It may help you understand your recovery if you had surgery 6 weeks to 3 months ago.
DenizliAges 20–65 - NCT06935799Recruiting
Freezing for 1 vs 2 minutes after Nuss surgery
This study compares how well one minute of freezing (cryoanalgesia) works versus two minutes to control pain after Nuss surgery for pectus excavatum. It will help find the best way to freeze nerves to reduce pain after surgery.
Warsaw, Wybierz WojewództwoAges 12–18 - NCT07159867Enrolling by invitation
Hypermobility-related problems in young women with anorexia
This study is for young women with anorexia nervosa or atypical anorexia nervosa. It explores whether they also have joint hypermobility (loose, flexible joints) and related problems, to help improve care for both conditions.
Gothenburg, Västra Götaland CountyAges 13–25 - NCT07162168Recruiting
Using AI to measure bone age from abdominal CT scans
This study uses artificial intelligence to estimate bone age from standard abdominal CT scans. It may help researchers understand how bone age relates to health conditions without extra X-rays.
BeijingAges 18 years+ - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.