Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07075276Recruiting
Comparing a new growth factor treatment to standard care for jaw joint pain
This study tests a new treatment for a common jaw joint problem called disc displacement. It compares a concentrated growth factor from your own blood to standard care to see which helps more with pain and jaw movement.
Damietta, New DamiettaAges 18–45 - NCT07066709RecruitingPhase 2
Hip pain study after hip surgery
This study tests if a second hip surgery can help people who still have pain at least 6 months after their first hip surgery. It may help you if you have ongoing hip pain and haven't needed strong pain pills.
Madison, WisconsinAges 18–45 - NCT07065591RecruitingEarly Phase 1
Metformin, Exercise, and Diet for Knee Osteoarthritis
This trial tests whether a common diabetes drug (metformin) combined with exercise and a healthy diet can help people with knee osteoarthritis who are overweight.
Hong Kong, Sandy BayAges 40–80 - NCT07068880Recruiting
New flexor tendon repair technique study for adults
This study tests a new device for fixing certain torn tendons in the hand and arm. It may help if you have an injury in specific areas (zones 2-5) and fit size requirements.
Orlando, FloridaAges 22–88 - NCT07072091Recruiting
Whole-body vs shoulder physiotherapy for volleyball players
This trial compares two physiotherapy approaches for volleyball players: one focusing only on the shoulder, and another looking at the whole body. It aims to find which method helps prevent or reduce shoulder problems.
Trieste, TriesteAges 17–30 - NCT07065266Enrolling by invitation
Pain survey for ACL knee surgery patients
This trial is testing a simplified pain questionnaire for people who are having ACL knee surgery. The goal is to see if this shorter questionnaire can effectively measure pain levels after surgery.
Redwood City, CaliforniaAges 18 years+ - NCT07069179Recruiting
Choose to Move replacement study for older adults
This study tests a program called Choose to Move Replacement Ready (CTM-RR) designed for older adults. It looks at how well activity coaches and healthcare referral partners can help people get active.
Vancouver, British ColumbiaAges 50 years+ - NCT07072676Enrolling by invitation
Can a walker help prevent falls in neuromuscular disease?
This study tests if using assistive walking devices, after a short training period, can lower the risk of falls in people with neuromuscular diseases. It aims to help you stay steady and safe on your feet.
Bad FeilnbachAges 65–65 - NCT07066228Recruiting
Rebuilding bone using a patient's own stem cells
This trial tests whether using a patient's own bone marrow stem cells can help repair large gaps in the shin or arm bones that haven't healed on their own. The stem cells are grown in a lab to create new bone tissue, which may avoid the need for metal implants or donated bone.
Xinxiang, HenanAges 18–55 - NCT07069959Recruiting
Measuring leg muscle recovery after ICU breathing support
This study checks how leg muscles recover after being in the ICU on a breathing machine. It uses a strength test and a special ultrasound to measure muscle health.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07066852Enrolling by invitation
Hip screening for Turkish newborns at risk
This trial checks how well a hip screening program works for Turkish babies born in a specific hospital. It aims to find developmental hip problems early so they can be treated.
Ankara, AnkaraAges Any age - NCT07065747Recruiting
Understanding inflammation in uveitis using advanced eye imaging
This study uses a special eye scan (OCT) to measure and classify inflammatory cells inside the eye. It aims to better understand different types of uveitis and improve diagnosis and treatment.
Portland, OregonAges 5–85 - NCT02842424RecruitingPhase 4
Ramipril for walking pain from blocked leg arteries
This study tests whether ramipril (a blood-pressure medicine) can improve leg muscle problems linked to poor blood flow in people with chronic claudication—pain that limits walking. It’s mainly looking at changes related to oxidative stress and muscle scarring (fibrosis).
Omaha, NebraskaAges 18–90 - NCT05418218Recruiting
International headache registry for people with headache diagnoses
This study collects information from people who have headaches to better understand different headache types. You may help researchers by keeping headache records and allowing follow-up over time.
Hangzhou, ZhejiangAges 4–99 - NCT05519007Recruiting
Tested no-rinse cleanser to prevent joint infections after surgery
This study compares a no-rinse cleaning solution used during primary joint replacement surgery versus the usual care. It looks at how many people still have a joint infection 90 days after surgery.
Manhasset, New YorkAges Any age - NCT07058636Recruiting
Nerve block plus trigger point shots for neck pain relief
This study tests if adding a nerve block to standard trigger point injections provides better relief for people with chronic neck pain caused by myofascial pain syndrome.
AnkaraAges 18–65 - NCT07058623Recruiting
Nurse-led telehealth vs in-person follow-up after knee replacement
This trial compares follow-up care with a nurse via video calls or phone versus in-person visits after your first total knee replacement. It aims to see if telehealth is as good as in-person for your recovery.
Hong KongAges 18 years+ - NCT07059065Recruiting
New bone graft for spinal fusion surgery
This trial tests a new bone graft material called FIBERGRAFT Aeridyan for people needing spinal fusion to stabilize their lower back. It aims to see if it helps bones heal together safely and effectively.
Sacramento, CaliforniaAges 18 years+ - NCT07062588RecruitingPhase 2
AGA2115 for osteogenesis imperfecta in adults with COL1A1/COL1A2 variations
This trial tests a new drug called AGA2115 for people with osteogenesis imperfecta (also known as brittle bone disease) who have a confirmed genetic change in the COL1A1 or COL1A2 genes. The study aims to see if the drug can help strengthen bones and reduce fracture risk.
Phoenix, ArizonaAges 18–75 - NCT07058662RecruitingPhase 1/Phase 2
Gene therapy study for Duchenne muscular dystrophy in boys 4-8
This study tests a new gene therapy called BBM-D101 for boys with Duchenne muscular dystrophy. The goal is to see if it is safe and can help improve muscle function. It is for boys aged 4 to 8 who can still walk.
Beijing, Beijing MunicipalityAges 4–9 - NCT07062978RecruitingPhase 3
Comparing QL1206 to Prolia for postmenopausal osteoporosis
This trial tests a new medication, QL1206, against an approved drug, Prolia, to see if it works as well for treating osteoporosis in postmenopausal women. You may be eligible if you have low bone density and at least one risk factor for fractures.
GuizhouAges 50–85 - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT07061782Recruiting
Neck stretching techniques for IT workers with upper cross syndrome
This trial compares two types of stretching exercises to see which one helps reduce neck and shoulder pain in IT professionals with upper cross syndrome. It may help you move better and feel less pain from long hours at the computer.
IslamabadAges 20–40 - NCT07055971Enrolling by invitation
Pain education and brain training for fibromyalgia
This trial tests whether a program that teaches you about pain and helps your brain control pain better can improve fibromyalgia symptoms. It also looks at how emotions play a role.
Granada, AndalusiaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.