Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07590674Recruiting
Balance training for competitive tennis players
This study compares two types of balance training to see which one better improves tennis players' ability to move quickly and change direction on court. You'll do either reactive balance exercises (responding to sudden movements) or traditional balance exercises over the study period.
IslamabadAges 18–25 - NCT07588087Recruiting
Shoulder Release Therapy for Frozen Shoulder Pain
This study tests whether adding a specific muscle-release technique to shoulder exercises helps reduce pain and improve movement in frozen shoulder (adhesive capsulitis). Frozen shoulder causes stiffness and pain that limits arm movement; this trial explores whether combining two physical therapy methods works better than standard care.
Islamabad, Punjab ProvinceAges 35–70 - NCT07590882Enrolling by invitation
Sports Recovery After Hip Realignment Surgery
This study follows patients who had hip socket realignment surgery (PAO) to understand how well they return to sports and physical activities. Researchers will review medical records from the past 7+ years to learn what helps patients get back to the sports they love.
BolognaAges 12–40 - NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65 - NCT07593235Recruiting
Treating Forward Head Posture with Two Physical Therapy Techniques
This study compares two hands-on treatment methods for forward head posture—a common problem where your head juts forward. Researchers want to see which technique works better at improving your posture and reducing strain on your neck and upper back.
Islamabad, Punjab ProvinceAges 18–40 - NCT06721104Recruiting
Balance and jaw health in autism
This study looks at balance, jaw joint function, and social skills in people with autism. It aims to understand how these areas are connected and could help improve care.
KirikkaleAges 4–21 - NCT06716281RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This study tests a new stem cell treatment for knee osteoarthritis. It aims to see if injecting these cells into the knee can reduce pain and improve function compared to other treatments.
ShanghaiAges 40–80 - NCT06720376Recruiting
Uveitis and arthritis study for Turkish patients
This study follows people with uveitis (eye inflammation) to learn more about how it relates to spondyloarthritis (arthritis of the spine). You may be able to join if you have uveitis, but not if you already had spondyloarthritis before your uveitis started or if your uveitis is caused by an infection.
Istanbul, MaltepeAges 18–75 - NCT06720779Recruiting
Virtual rehab platform for knee replacement patients
This trial tests a virtual rehab platform for people recovering from knee replacement surgery. It may help you do your rehab exercises more easily at the hospital.
Barakaldo, Basque CountryAges 18–85 - NCT04678635Recruiting
Brain stimulation study for autoimmune muscle disease
This trial tests whether a noninvasive brain stimulation treatment can help people with systemic autoimmune muscle diseases. It may improve symptoms by changing how the brain and muscles communicate.
São Paulo, São PauloAges 18–70 - NCT05962463Recruiting
Compare two pain injections for advanced knee arthritis
This trial compares pulsed radiofrequency therapy versus a targeted nerve pain block to help reduce knee pain from advanced osteoarthritis. You might join if you have knee osteoarthritis in the more severe range (Kellgren-Lawrence grade 3–4) and meet safety requirements.
LjubljanaAges 45–100 - NCT06184100Recruiting
Online Self-Management Program for Teens with JIA
This study tests an online self-management program for teens with newly diagnosed JIA. It helps you learn skills to manage your condition, connect with others, and feel more in control.
Calgary, AlbertaAges 12–17 - NCT07580222Recruiting
Using Mobile Technology to Track Knee Arthritis Health
This study uses smartphone or tablet technology to measure how your knee osteoarthritis (wear-and-tear arthritis) changes over time. You'll be helping researchers understand how well a previous arthritis treatment works by tracking your knee health at home.
Palo Alto, CaliforniaAges 30 years+ - NCT07578610Recruiting
Registry study of symptom descriptions using OpenGenome platform
This is an observational registry study that collects and analyzes symptom descriptions from patients using the OpenGenome platform. The goal is to better understand and extract health information from how people naturally describe their symptoms.
Friedrichshain, State of BerlinAges 18 years+ - NCT07583056Recruiting
Brain Stimulation Treatment for Fibromyalgia Pain
This study tests whether a non-invasive brain stimulation treatment called tDCS (transcranial direct current stimulation) can help reduce fibromyalgia pain. You'll use a small device at home that sends mild electrical currents to your scalp, and researchers will monitor your progress via video calls.
ValenciaAges 18 years+ - NCT07579936RecruitingPhase 2
SAL056 bone-strengthening treatment for postmenopausal osteoporosis
This study tests a new injectable medication called SAL056 to strengthen bones and prevent fractures in postmenopausal women with osteoporosis. Researchers want to find the best dose and how often to give it.
Beijing, Beijing MunicipalityAges 45–80 - NCT07580716RecruitingPhase 2
Knee Injection Treatment for Moderate Osteoarthritis
This study tests a new cell-based injection (Allocetra) directly into the knee joint for people with moderate osteoarthritis who haven't benefited from other treatments. The goal is to reduce pain and improve knee function.
Longwood, FloridaAges 64 years+ - NCT07583563Recruiting
Observational study of octreotide depot injections for acromegaly
This study watches how patients with acromegaly respond to octreotide, a medication given as injections under the skin. Researchers will collect information about how well the treatment works and any side effects you experience.
AachenAges 18 years+ - NCT07578831Recruiting
Neck Pain Relief: Comparing Two Exercise Methods
This study compares two types of therapeutic exercises—Kendall and Feldenkrais—to help reduce neck pain and improve posture in people with upper crossed syndrome (a common postural condition where neck and shoulder muscles become tight and weak). You'll do one type of exercise program to see which helps your neck pain and function better.
Lahore, Punjab ProvinceAges 20–50 - NCT07585305Recruiting
Blood Flow Restriction Training for Knee Pain in Athletes
This study compares two types of exercise—resistance training and cycling—both using a special technique that temporarily reduces blood flow to your leg muscles. The goal is to see which approach works better for reducing knee pain and improving strength in athletes with patellofemoral pain (pain around or behind the kneecap).
IslamabadAges 18–40 - NCT07582367Recruiting
How Foot Arches Affect Walking and Thinking in Older Adults
This study looks at whether the shape of your foot arches—how high or flat your arches are—affects how you walk and your thinking and memory skills. Researchers want to understand if foot structure plays a role in these abilities as we age.
Balıkesir, BigadiçAges 65 years+ - NCT07581470Recruiting
Steroid Injection to Reduce Pain After Hip Replacement Surgery
This study tests whether adding a steroid medication (dexamethasone) through an IV line during hip replacement surgery reduces pain afterward. Researchers will compare three different doses to see which works best when combined with a nerve block (numbing medicine injected near the hip).
PoznanAges 18–100 - NCT07580365Recruiting
Virtual Reality Training for Kids With Muscle Diseases
This study tests whether a virtual reality-based exercise program can help children and teens with diagnosed muscle diseases improve their strength and function. Participants use a special exercise bike while wearing a VR headset to make training more engaging.
Bosisio Parini, LCAges 6–18
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.