Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06056180Recruiting
Motor imagery training for balance in older adults
This study tests whether imagining moving your body (motor imagery training) can improve balance in older adults. It will compare this mental practice with usual activities to see if it helps prevent falls and improves stability.
Menteşe, MuğlaAges 60–80 - NCT07505914Recruiting
Breathing exercises for better thinking in older adults
This trial tests whether simple breathing exercises can improve memory and thinking skills in adults aged 65 and older. You would attend two sessions each week for 8 weeks.
IstanbulAges 65 years+ - NCT07021287Recruiting
Cold therapy after knee replacement surgery
This study compares different cold therapy programs to see which works best for pain and swelling after total knee replacement. Everyone in the study receives cold therapy, and the researchers will track recovery outcomes.
Yiwu, ZhejiangAges 18 years+ - NCT07660926Recruiting
Better Hamstring Activation With a Feedback Device
This study tests a device called Hamshell that uses electrical signals from your muscles (EMG) to give feedback on how well your hamstring is working. It may help you activate your hamstring better during exercise.
MuttenzAges 18–40 - NCT06474429Recruiting
Movement test for chronic low back pain recovery
This study tests whether a simple movement screening test can help physical therapists decide when someone with chronic lower back pain is ready to stop treatment. If you join, you will do a few basic movements to see how your back is doing.
Plano, TexasAges 18–49 - NCT07480057Recruiting
Bone health changes after liver transplant
This study tracks how liver transplantation affects your bone density and mineral metabolism. It aims to find changes early, which can help prevent fractures later.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT07658326Recruiting
Stress and rotator cuff surgery study
This study looks at how stress before surgery might affect recovery in people having rotator cuff surgery. You may be able to join if this is your first surgery for a torn rotator cuff and you don't have certain other health problems.
CornebarrieuAges 18 years+ - NCT07190339Recruiting
Nerve block for hip osteoarthritis pain
This trial tests whether blocking specific nerves in the hip and groin area can reduce pain from hip osteoarthritis when standard treatments like painkillers or physical therapy haven't worked.
AnkaraAges 18–75 - NCT04106674Recruiting
Treating displaced shoulder fractures: non-surgery vs surgery options
This trial compares non-surgical care with two different surgical fixation methods for a displaced two-part shoulder (upper arm) fracture. It aims to see which approach leads to the best recovery and function.
Lørenskog, OsloAges 60–85 - NCT07634627Recruiting
Understanding why teens get scoliosis – a protein study
This study looks at how proteins in the blood may help us understand why teenagers develop scoliosis (a sideways curve in the spine). If you have mild to moderate scoliosis and are getting care at Children's Hospital Colorado, you may be able to join this study to help researchers learn more about the condition.
Aurora, ColoradoAges 10–17 - NCT04609735Recruiting
Compare manual therapy, exercise, and ultrasound for golfer’s elbow
This study compares two treatment plans for golfer’s elbow—manual therapy plus exercise, and whether adding ultrasound helps more. It aims to reduce elbow and inner-forearm pain and improve how well you can use your arm.
Fort Wayne, IndianaAges 18–60 - NCT06478485Recruiting
A new way to plan neck surgery using MRI measurements
This trial is testing a new method to plan cervical spine surgery called laminoplasty. The goal is to use special measurements from MRI scans to better decide how to operate. This could lead to better recovery for people with spinal cord compression in the neck.
Nantong, JiangsuAges 18 years+ - NCT06466408Recruiting
Enzyme supplement and exercise in older adults
This trial is testing if taking a fruit and vegetable enzyme supplement can help older adults recover better after short, intense exercise using video games. You would exercise and take the supplement to see how it affects your muscles, breathing, and blood.
TainanAges 65 years+ - NCT06025331Recruiting
BIO-RSA vs standard reverse shoulder replacement study
This study compares two types of reverse shoulder replacement: one that uses a bone graft (BIO-RSA) and one that doesn't. It aims to see if the BIO-RSA method gives better pain relief and function for people with arthritis, large rotator cuff tears, or failed prior cuff surgery.
Skien, TelemarkAges 45–80 - NCT06138236RecruitingEarly Phase 1
Comparing shockwave therapy and collagen for plantar fasciitis
This study tests whether shockwave therapy or collagen supplements work better for reducing heel pain from plantar fasciitis. If you have heel pain and haven't had foot surgery, you may be able to join.
BariAges 18–80 - NCT07501468Recruiting
Comparing two breathing devices for shoulder surgery
This trial tests two types of breathing tubes (SafeLM and I-gel) to see which works better for people having shoulder surgery while sitting up. It aims to find a safer way to keep your airway open during the procedure.
Ankara, AnkaraAges 18–80 - NCT06025448Recruiting
Comparing two types of reverse shoulder replacement
This study compares two types of reverse shoulder replacements: one that uses a small piece of your own bone (BIO-RSA) and another that uses a special metal implant (MIO-RSA) to fill the socket. The goal is to see which one stays more stable in the bone after surgery.
OsloAges 45–80 - NCT07477860RecruitingPhase 1
Achilles tendon pain treatment trial
This trial tests a minimally invasive treatment for chronic Achilles tendon pain that hasn't improved with at least 3 months of rest, therapy, or other non-surgical care. It aims to help people who want to avoid surgery.
Libertyville, IllinoisAges 25–80 - NCT06462209Recruiting
Ladder vs. plyometric training for female cricket players
This study compares two types of training—ladder drills and plyometric jumps—to see which one might improve your performance on the cricket field. If you're a healthy female cricket player who hasn't had a recent leg injury, you could help find out which training works best.
Lahore, Punjab ProvinceAges 18–25 - NCT06023212RecruitingPhase 1/Phase 2
Tranexamic acid to prevent bleeding in spine surgery for lung cancer
This trial tests if a medicine called tranexamic acid can help reduce bleeding during surgery for lung cancer that has spread to the spine. It may be an option if you have a single tumor in your spine and are having separation surgery.
Hangzhou, ZhejiangAges 10–80 - NCT07498608Enrolling by invitation
Running training study for recreational runners aged 20-45
This study compares two types of running workouts to see which helps you run faster and improve your body shape. It is for recreational runners living near Bogotá, Colombia, who have some experience and a GPS watch.
Bogotá, Bogota D.C.Ages 20–45 - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT07509866Recruiting
Comparing pain relief options for knee replacement surgery
This trial tests two different numbing medicines for knee replacement surgery. It compares a long-acting numbing medicine (liposomal bupivacaine) with a standard one (ropivacaine) mixed with other drugs to see which provides better pain control. The goal is to find a way to reduce pain and improve recovery.
Wuhan, HubeiAges 18–80 - NCT06643780RecruitingPhase 4
Denosumab for muscle loss in older adults with osteoporosis
This study tests whether a drug called Denosumab, which is used to treat bone loss, can also help improve muscle strength and mass in older adults who have both osteoporosis and sarcopenia. If you qualify, you would receive the drug and be monitored over time to see if it helps your bones and muscles.
Hong KongAges 65 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.