Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT03749538Recruiting
Brain stimulation test for autoimmune muscle weakness
This trial tests whether a noninvasive brain stimulation technique (through the scalp) can improve muscle weakness in people with certain autoimmune muscle diseases. It may help by changing brain signals that affect how muscles work.
São PauloAges 18–80 - NCT03092180Recruiting
Tests a treatment approach for certain muscle inflammation diseases
This trial looks at treatment strategies for people with idiopathic inflammatory myopathies, which are illnesses where the immune system attacks muscles. It may help improve how treatment is chosen and optimized for this group of conditions, but it specifically excludes several related muscle diseases.
São PauloAges 18 years+ - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT06464770Recruiting
Improving infection prevention before shoulder surgery
This study compares different ways to clean the skin before shoulder surgery to prevent infection. It might help if you are going to have shoulder surgery and want safer, more effective infection prevention.
Seattle, WashingtonAges 18–89 - NCT06569836Recruiting
Study on digital program for chronic knee pain
This trial tests a digital program to help people manage chronic knee pain. If you are 55 or older and have had knee pain recently, this study may be a good fit.
Hong KongAges 55 years+ - NCT06718283Recruiting
A study of blood tests in young people with lupus
This study looks at blood test results in children and teenagers with lupus to see if they relate to how active the disease is or if it has caused long-term damage. It may help doctors better understand the disease.
SohagAges Up to 18 years - NCT06717568Recruiting
Using 3D camera to check scoliosis in teens
This trial tests a 3D depth camera to measure spinal curves in teens with scoliosis. It may help avoid repeated X-rays while tracking your curve.
Hangzhou, ZhejiangAges 10–18 - NCT04117334Recruiting
Finding the best brace timing for scoliosis in growing teens
This study looks at adolescent idiopathic scoliosis—a common sideways curve in otherwise healthy teens—and tests which bracing approach is best for teens who are still growing. It may help guide families on the most helpful brace type and when it’s likely to work best.
Hong KongAges 10–18 - NCT03582917RecruitingPhase 2
Vitamin D during rehabilitation for teen scoliosis
This study looks at whether vitamin D affects recovery during rehab for teens with idiopathic scoliosis (a sideways spine curve without a known cause). It may help the rehab process by improving vitamin D–related factors in growing teens.
AsvestochóriAges 10–18 - NCT07589127Recruiting
Nerve Block for Pain Relief During Knee Replacement
This study tests whether blocking a specific nerve in the knee can reduce pain and improve recovery after total knee replacement surgery. You would receive this nerve block alongside standard anesthesia to see if it helps you need fewer pain medications afterward.
Hjelset, Møre og RomsdalAges 18–80 - NCT07588555Recruiting
Two surgical approaches for lumbar spine narrowing
This trial compares two slightly different surgical techniques for treating lumbar spinal stenosis (a narrowing of the spinal canal that causes leg pain). Both procedures fuse one level of your spine to relieve pain, but use slightly different approaches through the side of the spine.
Guangzhou, GuangdongAges 40–70 - NCT07587242RecruitingPhase 3
Testing a New Therapy for DMD with Exon 44 Mutations
This study tests whether a new medicine called AOC 1044 (delpacibart zotadirsen) can help boys with Duchenne muscular dystrophy (DMD) who have a specific genetic mutation. The medicine works by helping the body skip a damaged part of the gene to make a functional protein.
Westmead, New South WalesAges 7–16 - NCT07586774Recruiting
Complete Denture Outcomes: 3D Printed vs. Traditional Design
This study compares two ways of making complete dentures (upper and lower teeth replacements): using newer 3D printing technology versus traditional milling methods. Participants will wear these dentures for 5 years and report how well they work and feel.
Chapel Hill, North CarolinaAges 18 years+ - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT07590674Recruiting
Balance training for competitive tennis players
This study compares two types of balance training to see which one better improves tennis players' ability to move quickly and change direction on court. You'll do either reactive balance exercises (responding to sudden movements) or traditional balance exercises over the study period.
IslamabadAges 18–25 - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT07592871Recruiting
Knee Injury and Arthritis Long-Term Health Study
This study follows patients with knee injuries or wear-and-tear arthritis over time to understand how these conditions develop and change. Your health information helps doctors learn what treatments work best and how to prevent problems.
Ningbo, ZhejiangAges 18–90 - NCT07588061Recruiting
Neck Pain Treatment: Mobilization and Posture Exercises
This study tests whether combining two types of physical therapy—manual joint mobilization and specific posture-strengthening exercises—can reduce neck and upper back pain and improve how you hold your body. You may qualify if you have persistent neck pain linked to poor posture.
Peshawar, KPKAges 18–45 - NCT07589218Recruiting
Ankle Flexibility and Looseness in Young Basketball Players
This study measures how flexible your child's ankles are during weight-bearing activities and checks if loose ligaments (the bands that support joints) play a role. Researchers want to understand ankle flexibility in young basketball players aged 8–15 to help prevent injuries.
Valencia, ValenciaAges 8–15 - NCT07593235Recruiting
Treating Forward Head Posture with Two Physical Therapy Techniques
This study compares two hands-on treatment methods for forward head posture—a common problem where your head juts forward. Researchers want to see which technique works better at improving your posture and reducing strain on your neck and upper back.
Islamabad, Punjab ProvinceAges 18–40 - NCT07587346Recruiting
Vibration and Relaxation for Athlete Girls With Triad Syndrome
This study tests whether whole-body vibration (gentle shaking platforms) and relaxation techniques can help teenage female athletes with the Triad Syndrome—a condition involving low energy intake, missing periods, and weak bones. The goal is to improve bone health and restore normal menstrual cycles.
CairoAges 14–16 - NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65 - NCT07591675Recruiting
Sprint and Plyometric Training vs. Traditional Strength Training in Rugby
This study compares two different training approaches—one combining sprints and jumping exercises, the other traditional strength training—to see which better improves speed, agility, and power in intermediate rugby players. Researchers will measure how these training styles affect your athletic performance and movement quality.
IslamabadAges 18–25
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.