Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07578168Enrolling by invitation
Kinesio Tape for Rotator Cuff Shoulder Pain
This study tests whether kinesiology tape (a special stretchy tape applied to the skin) can reduce pain and improve function in people with rotator cuff syndrome, a common shoulder condition. You'll be randomly assigned to receive the tape or a control treatment and tracked over several weeks.
Kırşehir, MerkezAges 18–65 - NCT07584356Recruiting
Comparing Shoulder Replacement Methods for Arthritis
This study compares two different surgical approaches for replacing a shoulder damaged by arthritis, but only in patients whose rotator cuff (the muscles that stabilize the shoulder) is still working well. The goal is to find which method works better for your specific situation.
Rochester, MinnesotaAges 60–85 - NCT07581457Recruiting
Tranexamic Acid to Reduce Bleeding in Scoliosis Surgery
This study tests whether a medication called tranexamic acid can safely reduce blood loss during surgery to straighten the spine in teenagers with idiopathic scoliosis (a curved spine with no known cause). The goal is to help patients need fewer blood transfusions and recover better.
PoznanAges 10–18 - NCT07580365Recruiting
Virtual Reality Training for Kids With Muscle Diseases
This study tests whether a virtual reality-based exercise program can help children and teens with diagnosed muscle diseases improve their strength and function. Participants use a special exercise bike while wearing a VR headset to make training more engaging.
Bosisio Parini, LCAges 6–18 - NCT07585305Recruiting
Blood Flow Restriction Training for Knee Pain in Athletes
This study compares two types of exercise—resistance training and cycling—both using a special technique that temporarily reduces blood flow to your leg muscles. The goal is to see which approach works better for reducing knee pain and improving strength in athletes with patellofemoral pain (pain around or behind the kneecap).
IslamabadAges 18–40 - NCT07578831Recruiting
Neck Pain Relief: Comparing Two Exercise Methods
This study compares two types of therapeutic exercises—Kendall and Feldenkrais—to help reduce neck pain and improve posture in people with upper crossed syndrome (a common postural condition where neck and shoulder muscles become tight and weak). You'll do one type of exercise program to see which helps your neck pain and function better.
Lahore, Punjab ProvinceAges 20–50 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT07582367Recruiting
How Foot Arches Affect Walking and Thinking in Older Adults
This study looks at whether the shape of your foot arches—how high or flat your arches are—affects how you walk and your thinking and memory skills. Researchers want to understand if foot structure plays a role in these abilities as we age.
Balıkesir, BigadiçAges 65 years+ - NCT07577362Recruiting
Core Training for Amateur Soccer Players
This study tests a specialized core (abdominal and back muscle) training program designed for amateur soccer players. Researchers want to see if this training improves performance and reduces injury risk in young athletes.
KarabükAges 18–35 - NCT07578935Recruiting
Stability and Jump Training After ACL Surgery
This study compares two types of exercise programs for people who had ACL (knee ligament) reconstruction surgery 1-3 years ago. The goal is to see which training approach—focusing on balance and stability or on jumping and power—helps restore better knee function and strength.
Lahore, Punjab ProvinceAges 20–40 - NCT07578220Recruiting
Ultrasound-guided acupotomy for ankylosing spondylitis
This study tests an ultrasound-guided needle procedure called acupotomy to treat ankylosing spondylitis, a type of arthritis that affects the spine. It might help reduce pain and improve movement.
Henan, ZhengzhouAges 18–75 - NCT07582510Recruiting
Telehealth vs. In-Person Physical Therapy for Golfer's Elbow
This study compares doing physical therapy exercises at home with video guidance versus attending in-person sessions for medial epicondylitis (golfer's elbow). The goal is to see which approach helps reduce pain and improve function better.
Banhā, BenhaAges 18–60 - NCT07583836Recruiting
Early vs. delayed surgery for spinal cord injury recovery
This trial compares whether having surgery sooner or waiting longer after a spinal cord injury helps patients recover better. Researchers will track how well patients regain movement and function over time.
RawalpindiAges 18–60 - NCT07583498Recruiting
Treating Muscle Stiffness After Spinal Cord Injury With Oxygen Therapy
This study tests whether brief periods of low oxygen (called acute intermittent hypoxia) can reduce muscle stiffness and tightness that develops after a spinal cord injury. Researchers believe this approach may help improve arm and hand function.
Chicago, IllinoisAges 18 years+ - NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT07581470Recruiting
Steroid Injection to Reduce Pain After Hip Replacement Surgery
This study tests whether adding a steroid medication (dexamethasone) through an IV line during hip replacement surgery reduces pain afterward. Researchers will compare three different doses to see which works best when combined with a nerve block (numbing medicine injected near the hip).
PoznanAges 18–100 - NCT06723730Recruiting
Mobilization and core strength for rotator cuff pain
This trial tests if adding a specific type of shoulder movement therapy and upper body core exercises can reduce pain and improve function in people with rotator cuff-related shoulder pain. It may help you if you have had shoulder pain for more than 6 weeks and it started after an injury.
Rawalpindi, Punjab ProvinceAges 18–65 - NCT02196155Recruiting
Botox or steroid shots for long-term heel pain
This trial compares botulinum toxin A (“Botox”) to steroid injections for chronic plantar fasciitis, a common cause of heel and foot pain. It aims to see which shot helps symptoms better when other treatments haven’t worked for at least 3 months.
BernAges 18–60 - NCT07573631Enrolling by invitationPhase 2
Long-term Safety Study of BMN 351 for Duchenne Muscular Dystrophy
This study continues treatment with an investigational medicine called BMN 351 for people with Duchenne muscular dystrophy (a genetic muscle-weakening condition). It checks whether the medicine remains safe and effective when used over a longer period, building on results from an earlier trial.
Milan, ItalyAges 4 years+ - NCT07574632Recruiting
Testing a New Scoliosis Brace for Growing Kids
This study tests a new brace called RESILIENT designed to help prevent scoliosis curves from getting worse in children. You'll wear the brace and the research team will track whether it helps slow or stop curve progression.
Wilmington, DelawareAges 9–16 - NCT07574385RecruitingPhase 2
Nerve Block Pain Relief After Bunion Surgery
This study tests a new nerve-blocking medication (ALX006) injected near the sciatic nerve to reduce pain after bunion surgery. The goal is to see if it provides better pain relief compared to standard care.
Millcreek, UtahAges 18 years+ - NCT05816226RecruitingPhase 3
Topical cream for jaw joint pain
This Phase 3 study tests a skin-applied treatment (a cream or gel) to reduce pain in the jaw joint (TMJ). You may benefit if you have TMJ pain and can safely use the study medication without conflicting treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT07576816Recruiting
Hip vs. Knee Exercises for Flat Feet
This study compares two types of exercises—one focusing on hip muscles and one on knee muscles—to see which better improves flat feet, balance, and leg strength. If you have flexible flat feet without pain, this trial may help you strengthen your feet and improve stability.
Faisalābad, Punjab ProvinceAges 25–40
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.