Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07404514Recruiting
Study of Long-Term Ulnar Hand Deficit
This study looks at how a rare hand condition (ulnar deficiency) changes over time. It may help doctors better understand the long-term outcomes for people with this condition.
Saint-MauriceAges 3–18 - NCT07402122Recruiting
Registry for duchenne and becker muscular dystrophy
This registry collects health information from people with Duchenne or Becker muscular dystrophy using a telemedicine platform. Joining helps doctors better understand the disease and may improve future care.
GrazAges Any age - NCT07402447Recruiting
Leg strengthening for knee osteoarthritis and walking
This study tests if strengthening your thigh and calf muscles can improve walking in people with knee osteoarthritis. It may help you walk better and feel more stable.
Peshawar, Khyber PakhtunkhwaAges 40–60 - NCT07407036Recruiting
Virtual reality rehab for wrist instability
This study tests whether adding virtual reality exercises to standard physical therapy helps people with a specific wrist ligament injury. It compares usual rehab with a program that uses fun, virtual-reality games to improve strength and control.
IstanbulAges 18–65 - NCT07400146RecruitingPhase 4
Numbing medicine for pain relief in laparoscopic surgery
This trial tests if numbing medicine (bupivacaine with epinephrine) placed over the diaphragm during laparoscopic surgery can reduce shoulder and other pain. It may help patients undergoing gynecologic laparoscopy recover more comfortably.
Los Angeles, CaliforniaAges 18 years+ - NCT07399834Enrolling by invitation
Studying two surgical methods for shoulder separation repair
This study compares two surgery techniques (using one tunnel or two tunnels) to fix a shoulder separation (AC joint injury). It may help surgeons choose the best method for healing and recovery.
Chon Buri, Changwat Chon BuriAges 18–45 - NCT07405450Recruiting
Robotic walking training for better mobility
This study tests a robotic walking trainer (Trexo) to see if it helps improve walking. It is for people who can safely use the robot and stick to the training plan.
Calgary, AlbertaAges Any age - NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07401732Recruiting
Dysphagia in rheumatoid arthritis study
This study looks at swallowing problems (dysphagia) in people with rheumatoid arthritis to understand how common they are and what might cause them. It uses a flexible scope through the nose to examine swallowing function.
Tanta, ElgharbiaAges 18 years+ - NCT07404384Enrolling by invitation
Slow breathing and resistance exercise for fibromyalgia
This study tests whether combining slow breathing exercises with light weightlifting (biceps curls) can help women with fibromyalgia feel better. It focuses on improving symptoms through a simple home-based routine.
Málaga, MálagaAges 18 years+ - NCT07404046Recruiting
Comparing tendon grafts for ACL surgery
This trial compares two types of grafts using the semitendinosus tendon for ACL reconstruction. It aims to see if adding a part of the tendon's muscle improves healing and stability after surgery.
ZagrebAges 18–50 - NCT07398872Enrolling by invitationPhase 1
Gene therapy trial for children with ML4
This trial tests a gene therapy given by a one-time injection into the spinal fluid for children with Mucolipidosis type IV. It aims to see if the therapy is safe and can help slow or stop the disease.
Hangzhou, ZhejiangAges 1.5 years–8 years - NCT07402408Recruiting
Blood flow restriction training for knee osteoarthritis
This trial tests whether using a special band to limit blood flow during exercise can help reduce pain and improve movement in people with mild knee osteoarthritis. It may be an option if you have knee pain and stiffness but no other serious health conditions.
Islamabad, FederalAges 40–60 - NCT07401758Recruiting
Shockwave therapy for knee tendon pain
This study tests whether a noninvasive treatment called shockwave therapy can help reduce pain and improve function in people with patellar tendinitis, a common overuse injury of the knee tendon. It may be a good option for you if you have moderate knee pain and are otherwise healthy.
Guangzhou, GuangdongAges 18–45 - NCT07406893Recruiting
Reducing Infection Risk in Shoulder Replacement Surgery
This trial tests whether a special gel (Prontosan) applied during shoulder replacement surgery can reduce the risk of infection. It is for men having their first shoulder replacement.
St Louis, MissouriAges 18 years+ - NCT07405827Recruiting
Shoulder instability surgery study in France
This study follows patients who have surgery for shoulder instability, like Bankart repair or the Latarjet procedure. It helps doctors learn which treatments work best over time.
Paris, Île-de-France RegionAges 7 years+ - NCT07405060Recruiting
How age and muscle fatigue affect balance and control
This study looks at how getting older and muscle tiredness change your ability to keep your balance and control your movements. It may help explain why some people are more likely to fall.
TaoyuanAges 20–85 - NCT07404618Recruiting
Video pain relief study for older adults
This study tests a video program to help older adults with ongoing muscle or joint pain learn skills to manage pain and improve daily life. It may be a good fit if pain has been bothering you most days for at least 3 months and gets in the way of your normal activities.
Providence, Rhode IslandAges 55 years+ - NCT07400848Recruiting
Symptoms and recovery after COVID-19 vaccine
This study looks at people who developed new, long-lasting symptoms after a COVID-19 vaccine. It aims to understand their symptoms, do lab tests, and see how they recover over time.
BernAges 18 years+ - NCT07403929Recruiting
Fermented grape juice for fibromyalgia symptoms
This trial tests whether drinking fermented grape juice can help relieve fibromyalgia symptoms like pain and cramping. If you are a woman between 20 and 40 with mild excess weight and fibromyalgia, you may be eligible.
Istanbul, IstanbulAges 20–40 - NCT07406685RecruitingPhase 4
Comparing two bone medicines after stopping denosumab
This study compares two medicines (ibandronate and zoledronic acid) to see which one works better at keeping bones strong after stopping denosumab (Prolia). It's for postmenopausal women with mild to moderate bone thinning.
TaipeiAges 50–85 - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT06826898Recruiting
Hydrogel to prevent scar tissue after ankle ligament repair
This trial tests a special gel placed during ankle ligament repair surgery to see if it prevents painful scar tissue from forming. It might help people with chronic ankle sprains who need surgery.
ChanghuaAges 18–60 - NCT06828016Recruiting
Foot Reflexology for Chronic Low Back Pain
This study tests whether foot reflexology—a gentle massage of the feet—can help relieve chronic low back pain that has lasted more than 12 weeks. It is a safe, non-drug approach that may be a good option for people looking for a natural way to manage their pain.
New Taipei CityAges 18–100
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.