Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT06154694Recruiting
Shoulder joint patterns in arthritis patients
This study looks at how shoulder arthritis affects joint movement patterns. It compares patients with arthritis, healthy volunteers, and people who had a shoulder replacement that later needed a revision.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06151834Recruiting
Finger joint fusion study using KeriFuse implant
This trial tests a small metal implant (KeriFuse) that fuses the arthritic joint at the tip of your finger to reduce pain. It's for people with finger arthritis who are healthy enough for surgery.
NiceAges 18 years+ - NCT06716294Recruiting
Radiofrequency ablation and stabilization for spine tumors
This trial tests a treatment that uses heat to destroy active spine tumors from cancer that has spread, followed by stabilizing the bone. It aims to see if the treatment works by using a special scan (PET-CT) to confirm the results.
Athens, AthensAges 18–90 - NCT07356674Recruiting
Surgery for Meniscus Tear with Mild Bow Legs
This trial tests a new surgical approach for a specific type of meniscus tear (the cartilage that cushions the knee) in people who have a mild bow-legged (varus) knee. It combines a small bone cut near the knee with arthroscopic repair to fix the tear.
Shenzhen, GuangdongAges 35–75 - NCT06132750Recruiting
Long-term study of LAMA2 and SELENON muscle conditions
This study follows people with LAMA2-related muscular dystrophy or SELENON-related myopathy over 5 years to understand how the condition changes over time. It may help you by tracking your disease progression and contributing to future research.
Nijmegen, GelderlandAges 1 day–100 years - NCT07649356Recruiting
Estrogen and Muscle Function in Menopausal Women
This study compares how estrogen affects muscle strength and fitness in women before and after menopause. It aims to understand how hormonal changes during menopause impact physical health and may help researchers develop better support for women during this life stage.
AarhusAges 47 years+ - NCT06127316Recruiting
Heel lift height and foot pressure with custom braces
This study tests if changing the height of a heel lift in a custom foot brace can improve how weight is distributed on your foot after a serious ankle or hindfoot injury. If you have pain when walking, this could help find better ways to reduce that pain.
Iowa City, IowaAges 18–65 - NCT06126614RecruitingPhase 3
Infection prevention in joint replacement surgery
This trial tests a way to prevent infections for people getting a hip or knee replacement. It compares different methods to see which works best and may help lower your risk of infection after surgery.
Hamilton, OntarioAges 18 years+ - NCT06119542Recruiting
GlycOrtho: Endothelial damage in major spine surgery
This study looks at how major spine surgery affects the inner lining of blood vessels. It measures a substance called syndecan-1 in the blood to understand this damage.
Bologna, BOAges 12–75 - NCT07062978RecruitingPhase 3
Comparing QL1206 to Prolia for postmenopausal osteoporosis
This trial tests a new medication, QL1206, against an approved drug, Prolia, to see if it works as well for treating osteoporosis in postmenopausal women. You may be eligible if you have low bone density and at least one risk factor for fractures.
GuizhouAges 50–85 - NCT06118892Recruiting
Knee implant study for inner knee pain from arthritis
This trial is testing a new knee implant designed to relieve pain on the inner side of the knee caused by osteoarthritis. It is for people who have not gotten enough relief from other treatments like physical therapy or injections.
Sonoma, CaliforniaAges 25–65 - NCT07061782Recruiting
Neck stretching techniques for IT workers with upper cross syndrome
This trial compares two types of stretching exercises to see which one helps reduce neck and shoulder pain in IT professionals with upper cross syndrome. It may help you move better and feel less pain from long hours at the computer.
IslamabadAges 20–40 - NCT06562933Recruiting
Comparing electrical stimulation methods for chronic neck pain
This study compares two ways of using a type of electrical stimulation (interferential current) to treat long-term neck pain. It aims to find which method works better for people with chronic neck pain.
BoluAges 20–50 - NCT07244913Recruiting
Tools for chronic low back pain relief
This trial compares two types of handheld tools—one with metal instruments and one that uses sound waves—to see which works better for long-term low back pain. It may help if you have had pain for at least 6 months and feel tightness in your hamstrings.
Lahore, Punjab ProvinceAges 40–55 - NCT06487728Enrolling by invitation
Predicting muscle weakness in ICU patients with urine test
This study checks if a urine test and muscle measurements can help predict muscle weakness in critically ill patients. It aims to find an easier way to identify who might get weaker in the ICU.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT06221514Recruiting
Core vs Shoulder Training for Better Tennis Serve Speed
This study compares two types of training—core strengthening versus shoulder strengthening—to see which one helps tennis players hit faster serves. If you're a young adult player with some experience and no recent injuries or intense strength training, you may be able to join.
GizaAges 18–25 - NCT07170813Enrolling by invitation
Studying back braces for spine movement in healthy adults
This trial tests how different back braces affect how your spine moves. It is looking for healthy young adults to see if these braces change the way you bend or move your spine.
YalovaAges 18–35 - NCT07676630Recruiting
Brain Training Exercise for Female Volleyball Players
This study tests a special exercise program designed to improve how your brain and body work together during volleyball. It's for young female players in Turkey who are already playing competitively.
Istanbul, ZeytinburnuAges 16–21 - NCT07671807Recruiting
Adapted table tennis for people with disabilities
This trial tests if adapted table tennis can help improve fitness and well-being for people with disabilities. If you have a disability identification card and are interested in playing table tennis, you may be able to join.
Kaohsiung City, TaiwanAges 18–75 - NCT07611526Recruiting
How Your Body Responds to Special Exercise After Knee Surgery
This study looks at how tired your leg muscles get during a new type of exercise training (called blood flow restriction training) after knee replacement surgery. The goal is to understand how this training affects your recovery and strength.
Bonn, North Rhine-WestphaliaAges 18–85 - NCT07543614Recruiting
Frame Running for Kids and Teens With Movement Challenges
This study looks at whether Frame Running—a special bike activity—helps children and teens with cerebral palsy or other movement disabilities stay active and involved in their communities. Researchers want to see if regular Frame Running training improves participation and exercise for young people.
Odense, Region SyddanmarkAges 8–18 - NCT07582367Recruiting
How Foot Arches Affect Walking and Thinking in Older Adults
This study looks at whether the shape of your foot arches—how high or flat your arches are—affects how you walk and your thinking and memory skills. Researchers want to understand if foot structure plays a role in these abilities as we age.
Balıkesir, BigadiçAges 65 years+ - NCT07464899Recruiting
Body composition and lifestyles in athletes with disabilities
This study looks at body composition and lifestyle habits in athletes with disabilities who train regularly. It aims to learn how these factors relate to sports performance and health.
San Vicent del Raspeig, AlicanteAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.