Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07244068Recruiting
Mat Pilates for kids with upper crossed syndrome
This trial tests if Mat Pilates can reduce pain and improve posture in school-going children with a specific forward head and rounded shoulder condition called upper crossed syndrome. It may help your child feel better and stand straighter.
Lahore, Punjab ProvinceAges 8–16 - NCT07246109Enrolling by invitation
Knee Brace and Muscle Training for Osteoarthritis
This study tests whether wearing a knee brace and doing muscle training exercises can help people with knee osteoarthritis feel better and move more easily. It may be a good option if you have not had knee surgery and are not already in another treatment program.
TaichungAges 55 years+ - NCT07248475Recruiting
Battle rope training for elbow pain and stiffness after injury
This study tests whether battle rope exercises can help children ages 8–15 with elbow stiffness and pain after an injury. It aims to improve movement and reduce discomfort.
Lahore, Punjab ProvinceAges 8–15 - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT07248748Recruiting
Alexander technique for upper cross syndrome in teens
This study tests whether the Alexander Technique, a method that helps improve posture and reduce muscle tension, can help teenagers with upper cross syndrome (a common posture problem where the shoulders round forward and the head juts out). It may help them feel better and move more easily during school and daily activities.
Lahore, Punjab ProvinceAges 13–16 - NCT07248501Recruiting
Bulgarian exercises for leg function in children
This study tests a type of exercise called Bulgarian exercises to see if they help improve leg function in children. If your child can walk and follow instructions, they may be able to join.
Lahore, Punjab ProvinceAges 8–18 - NCT07245303Recruiting
How Light Affects Pain in Chronic Pain
This study looks at how different kinds of light might change pain levels in people with chronic widespread pain, like fibromyalgia. By using brain scans (MRI), researchers hope to find new ways to manage pain without medication.
Chapel Hill, North CarolinaAges 18 years+ - NCT07242729Recruiting
Compare two treatments for chronic heel pain from plantar fasciitis
This study compares two treatments—bone marrow aspirate and platelet-rich fibrin—to see which works better for long-lasting heel pain caused by plantar fasciitis. It may help if your pain has not improved with standard treatments like stretching or physical therapy.
São PauloAges 18–75 - NCT07245615Recruiting
Vibration therapy for neck dystonia
This study tests whether a gentle vibration device placed on the neck can improve head posture in people with cervical dystonia (neck muscle spasms). The goal is to find the best vibration strength to help reduce symptoms.
Minneapolis, MinnesotaAges 30 years+ - NCT07240961Recruiting
Nerve block for pain after hip replacement
This study tests whether a nerve block injection in the back (called an erector spinae plane block) can provide better pain relief after a first-time hip replacement. It may help reduce the need for strong painkillers.
ManoubaAges 18–85 - NCT07246122Recruiting
MRI-guided dynamic brace for scoliosis correction
This study tests a new MRI-guided brace system for teens with mild scoliosis (curves between 10 and 25 degrees). It aims to see if this dynamic brace is more comfortable and effective than traditional braces.
Tsim Sha Tsui, KowloonAges 10–16 - NCT07244081Recruiting
Movement therapy for arm use in children with cerebral palsy
This study tests whether a type of physical therapy called kinesiotherapy can improve arm and hand function and daily living skills in children with hemiplegic cerebral palsy (weakness on one side). It may help children who can follow simple directions and participate in therapy sessions.
Sialkot, Punjab ProvinceAges 8–13 - NCT07248514Recruiting
Pilates for kids with backpack-related back pain
This study tests if Pilates exercises can help children aged 12-16 who have back pain and poor posture from carrying heavy backpacks.
Lahore, Punjab ProvinceAges 12–16 - NCT07247825Recruiting
Needle treatment for shoulder tendon pain: single vs multi-filament
This study tests two types of a needle-based treatment (percutaneous electrolysis) for shoulder tendon pain. It aims to see if a single-filament or multi-filament approach works better for people with chronic supraspinatus tendon issues.
SalamancaAges 18–65 - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07240597Recruiting
Warm-up effects in young competitive swimmers
This trial tests how different warm-up routines affect performance in young competitive swimmers who train at least 10 hours a week. It could help improve their training or competition results.
Bagheria, PalermoAges 11–18 - NCT07243535Recruiting
Rhythm training for athletes after ACL surgery
This study compares two types of rhythm-based training (fractal vs isochronous cueing) to see which helps athletes regain better movement after ACL reconstruction. If you're an athlete who had ACL surgery less than two years ago and are now pain-free walking, you may be able to join.
Almada, Monte de CaparicaAges 15–35 - NCT07243327Recruiting
Shockwave therapy vs standard rehab for hip pain
This trial compares two treatments—shockwave therapy and conventional physical therapy—for long-lasting pain on the outside of the hip, often called trochanteric pain syndrome. It aims to find which option works better for people whose hip pain has persisted for months.
IstanbulAges 18–65 - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT07240259Enrolling by invitation
Using a donated aortic patch to rebuild a child's windpipe
This trial tests a new way to repair a child's windpipe using a piece of donated aorta (a blood vessel) as a patch. It's for children who have severe breathing problems from a narrowed or damaged windpipe and cannot have standard surgery.
TaipeiAges birth–18 years - NCT05858528Recruiting
Study following adults with skin psoriasis over time
This observational study is looking at adults with skin psoriasis and collecting real-world information about their condition and experiences. It may help researchers better understand psoriasis and how it affects people, without giving a new treatment.
Oxford, OxfordshireAges 18 years+ - NCT05917028Recruiting
Nonsurgical injections to reduce knee osteoarthritis pain
This study tests a procedure called transcatheter arterial micro-embolization (a targeted injection done through blood vessels) to lessen pain from knee osteoarthritis. It may help people who still have significant pain despite standard “non-surgical” treatments like therapy and joint injections.
Seoul, Seodaemun-guAges 50 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.