Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07724730Recruiting
Moving with and without music after a stroke
This study compares two types of movement practice for people recovering from a recent stroke. One group will do everyday tasks like walking and reaching, and the other will do the same movements but with a rhythmic beat to help with timing and coordination.
Daska KalanAges 40–60 - NCT06929273RecruitingPhase 3
Long-term safety study of KarXT for bipolar I mania
This study tests the long-term safety of KarXT for people with bipolar I disorder who are having a manic or mixed episode. It is for people who either completed a previous KarXT study or are new to the study and have moderate to severe mania symptoms.
Glendale, ArizonaAges 18–65 - NCT07637162Enrolling by invitationPhase 3
Safety study of AXS-14 for fibromyalgia
This study continues to monitor the safety of an investigational drug called AXS-14 in people with fibromyalgia who previously participated in another AXS-14 trial. Researchers want to make sure the treatment remains safe over time.
Arkansas City, ArkansasAges 18 years+ - NCT07044804Recruiting
Brain stimulation to improve language in Down syndrome
This trial tests a non-invasive brain stimulation technique to help adolescents and young adults with Down syndrome improve their language skills. It aims to see if this safe method can boost word-finding and speaking ability.
RomeAges 12–21 - NCT07291427Recruiting
Coiling for chronic subdural hematoma
This trial tests a procedure called coiling (placing tiny coils) to block the blood supply to a chronic subdural hematoma, a slow-growing blood collection around the brain. It may help reduce the need for surgery and improve recovery.
New York, New YorkAges 18 years+ - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT06931509Recruiting
How vision and body sense work after stroke
This study looks at how your brain combines what you see with what you feel in your body after a stroke. It may help understand how these senses work together to guide movement.
Saint-Etienne, FranceAges 18–80 - NCT07484217RecruitingPhase 3
Testing solriamfetol for depression with daytime sleepiness
This study tests if the drug solriamfetol can help people with major depression who also feel very tired during the day. It aims to improve both mood and daytime sleepiness.
Tucson, ArizonaAges 18–65 - NCT07050628Recruiting
Shunt flow test with wearable device
This study tests a small, wearable device that measures how fluid flows through your shunt during daily activities and sleep. It aims to help doctors better understand shunt function without needing repeated scans or hospital visits.
Chicago, IllinoisAges 2 years+ - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT07711626Recruiting
Foot massage and ear stimulation for head and neck cancer symptoms
This study tests whether foot massage (reflexology) and a mild nerve-stimulation device on the ear can help reduce side effects during chemotherapy and radiation for head and neck cancer.
Hualien CityAges 30–75 - NCT06814431Recruiting
Cancer risk in parkinson's patients with GBA gene mutation
This study looks at whether people with Parkinson's disease who have a specific gene change (GBA mutation) have a higher chance of developing cancer. It will help doctors understand the link between these conditions.
BrindisiAges 18 years+ - NCT07573631Enrolling by invitationPhase 2
Long-term Safety Study of BMN 351 for Duchenne Muscular Dystrophy
This study continues treatment with an investigational medicine called BMN 351 for people with Duchenne muscular dystrophy (a genetic muscle-weakening condition). It checks whether the medicine remains safe and effective when used over a longer period, building on results from an earlier trial.
Milan, ItalyAges 4 years+ - NCT06568367RecruitingPhase 3
Solriamfetol for shift work disorder (SUSTAIN trial)
This study tests a medication called Solriamfetol (Sunosi) to see if it helps people with shift work disorder stay awake and alert during their shifts. It is a Phase 3 trial, which means it is being studied in a larger group to confirm how well it works and check for side effects.
Auburn, AlabamaAges 18–65 - NCT06547827Recruiting
Robot-assisted rehab for stroke recovery
This study compares standard rehabilitation with therapy that uses robots and other digital tools to help people regain movement after a stroke. It's for people who had a first stroke within the last 6 months and have some arm, leg, or balance problems.
AcerenzaAges 18 years+ - NCT06219863Recruiting
Harness walking help for babies with Down syndrome
This study tests if a special harness can help babies with Down syndrome learn to walk earlier. It is designed for infants under 2 years old who can sit but are not yet walking.
Boston, MassachusettsAges Up to 2 years - NCT07573241Recruiting
Mindfulness for pain in multiple sclerosis
This study looks at what helps or makes it harder for people with MS to practice mindfulness. It tests if a mindfulness program can help with pain. You can join if you have MS, have moderate to severe pain most days, and can use a mobile phone to complete study tasks.
Seattle, WashingtonAges 18 years+ - NCT07500376Recruiting
Nutrition and Muscle Health in Lung Cancer Surgery
This study looks at how nutrition and muscle health before lung cancer surgery can affect recovery. It tests whether checking these factors can help predict and improve outcomes after surgery.
Samsun, SamsunAges 18 years+ - NCT07431125Recruiting
Surgery and hearing test link in one-sided conductive hearing loss
This study looks at how surgery findings relate to hearing tests in people with one-sided conductive hearing loss but a normal eardrum. It may help if you have a specific type of hearing loss where sound is blocked, and your eardrum is intact.
Asyut, Asyut GovernorateAges Any age - NCT07213284Recruiting
Healthy Mom pregnancy support app study
This study tests a web app to help pregnant people on Medicaid stay healthy. You may be able to join if you are early in your pregnancy, speak English, and have a smartphone.
Corunna, MichiganAges 18 years+ - NCT04833465Recruiting
Testing a new outcome measure in kids with rheumatology diseases
This study looks at how to measure treatment success in children with juvenile idiopathic arthritis (JIA), lupus (SLE), or fibromyalgia (FM). It may help doctors track symptoms more reliably over time.
Washington D.C., District of ColumbiaAges 5–21 - NCT07398417RecruitingPhase 3
Testing esreboxetine for fibromyalgia relief
This study tests a medicine called esreboxetine to see if it helps people with fibromyalgia. First, everyone gets the medicine, then some may switch to a placebo to see if the medicine keeps working better than no treatment.
Glendale, ArizonaAges 18 years+ - NCT07723144Recruiting
Identifying sleep apnea biomarkers
This study compares blood samples from people with moderate-to-severe sleep apnea and those without sleep apnea to find markers that could help diagnose or treat the condition. Half of those with sleep apnea will start CPAP therapy right away, while others wait before starting.
Bialystok, Podlaskie VoivodeshipAges 18–65 - NCT05962437Recruiting
Smartphone app for fibromyalgia pain management
This trial tests a smartphone app that teaches you skills to cope with fibromyalgia pain and improve your quality of life. It's based on a type of therapy called Acceptance and Commitment Therapy (ACT) that helps you accept pain and live a fuller life.
Barcelona, BarcelonaAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.