Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07596901RecruitingPhase 1/Phase 2
Testing Aritinercept for Generalized Myasthenia Gravis
This study tests a new drug called aritinercept to see if it can help people with generalized myasthenia gravis (a condition where muscles weaken over time). Researchers believe this drug may reduce the immune system activity that causes muscle weakness.
Pasadena, CaliforniaAges 18–85 - NCT07600684Recruiting
Smart medication reminder system for people with dementia
This study tests a device that reminds you to take your dementia medications and alerts a trusted caregiver if doses are missed. The goal is to help prevent medication mix-ups and keep you healthier.
Folsom, CaliforniaAges 65 years+ - NCT07595653Recruiting
Efgartigimod Treatment Experience in Generalized Myasthenia Gravis
This study follows people with generalized myasthenia gravis (a condition causing muscle weakness) who are already starting a medicine called efgartigimod as part of their regular care. Researchers want to understand how this treatment affects your daily life and overall experience with the disease.
Acquaviva delle FontiAges 18 years+ - NCT07599904Recruiting
Real-world study of Medtronic stroke treatment devices
This registry tracks how Medtronic's FDA-approved devices work in treating acute ischemic stroke (a type of stroke caused by a blood clot) in everyday clinical practice. Researchers collect information to understand device safety and effectiveness outside of formal clinical trials.
Flint, MichiganAges 18 years+ - NCT07596784RecruitingPhase 3
Ravulizumab for Generalized Myasthenia Gravis in Chinese Adults
This trial tests whether ravulizumab, a medication that blocks part of the immune system, can improve muscle weakness and fatigue in people with generalized myasthenia gravis (gMG). The study focuses on Chinese adults who have moderate-to-severe MG symptoms despite current treatments.
BeijingAges 18–130 - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Phoenix, ArizonaAges 55 years+ - NCT07598370RecruitingPhase 1
Testing LY3439539 for early-stage Alzheimer's disease
This study tests an experimental drug called LY3439539 in people with early-stage Alzheimer's disease. The drug is designed to target protein changes in the brain that may slow memory loss and cognitive decline.
Irvine, CaliforniaAges 50–85 - NCT07599670RecruitingPhase 1/Phase 2
Safety study of ABBV-1758 injection for Alzheimer's disease
This early-stage trial tests whether ABBV-1758, a new drug given by injection, is safe and effective for people with Alzheimer's disease. The drug targets amyloid, a protein that builds up in the brains of people with Alzheimer's.
Irvine, CaliforniaAges 50–90 - NCT07598708RecruitingPhase 2/Phase 3
Cleminorexton for Narcolepsy: A New Treatment Study
This study tests whether a new medication called cleminorexton helps people with narcolepsy (a condition causing severe daytime sleepiness) sleep better and feel more alert. You would take this medication instead of your current narcolepsy drugs for several months to see if it works.
Birmingham, AlabamaAges 18–70 - NCT07596485RecruitingPhase 1/Phase 2
RP-008 Plus Varenicline for Trigeminal Neuralgia Pain
This trial tests a new drug called RP-008 combined with varenicline (a quit-smoking medication) to relieve severe facial pain from trigeminal neuralgia. If you've already tried standard pain medications without enough relief, this combination might help reduce your pain attacks.
SherbrookeAges 18–80 - NCT06715995Recruiting
Light stimulation's effect on brain waves in healthy older adults
This trial tests if a special light (gamma light) can change brain wave patterns in healthy adults over 55. It aims to understand how light might help keep the brain sharp.
Taoyuan, GuishanAges 55 years+ - NCT06715449RecruitingPhase 2/Phase 3
Testing empagliflozin after a stroke with unknown cause
This trial tests if a diabetes drug called empagliflozin can help the heart's left atrium work better in people who have had a stroke with no known cause. You may join if you are getting a heart monitor device implanted to look for hidden irregular heartbeats.
Cambridge, CambridgeshireAges 18 years+ - NCT06714838RecruitingPhase 3
Rituximab for remission in chronic inflammatory demyelinating polyneuropathy
This trial tests a drug called rituximab to see if it can help people with chronic inflammatory demyelinating polyneuropathy (CIDP) achieve remission. It may offer a new treatment option for those who are newly diagnosed or who are on maintenance therapy with wear-off symptoms or failed withdrawal attempts.
AmsterdamAges 18–80 - NCT06715228Recruiting
Breathing exercise for sleep apnea
This trial tests a special breathing exercise program (called Shitali) to see if it helps people with mild or moderate sleep apnea who are not obese. If you qualify, you'll learn a gentle therapy that may improve your sleep without machines or medicine.
Dokki, Giza GovernorateAges 35–55 - NCT05008705Recruiting
Protein and muscle stimulation for hospitalized seniors
This trial tests whether increasing protein intake plus using a gentle electrical muscle stimulation device can help maintain or build muscle mass in older adults while they are hospitalized. It may help prevent muscle loss that can happen after short hospital stays.
São PauloAges 65 years+ - NCT06716125Recruiting
Lifestyle changes for obese men with sexual and hearing issues
This trial tests whether lifestyle changes can help obese men who have both sexual difficulties and ringing in the ears. It might improve your overall health and these symptoms.
Dokki, Giza GovernorateAges 35–45 - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07595783Recruiting
Brain Training for Children With ADHD Using Neurofeedback
This study tests a new type of brain training called neurofeedback to help children with ADHD. Children complete sessions where they learn to control their own brain activity, which may improve attention and focus.
BielefeldAges 6–13 - NCT07599306Recruiting
Telehealth Rehabilitation for Heart Patients After ICU Recovery
This study tests whether supervised remote rehabilitation exercises can help people recover better after a long ICU stay. Many patients struggle with weakness, memory problems, or mood changes after intensive care—this trial aims to improve those symptoms through video-guided therapy.
Milan, MilanoAges 30–75 - NCT07601841Recruiting
Light therapy to improve sleep after brain injury
This study tests whether light therapy can help people sleep better after a traumatic brain injury (TBI). Researchers will use MRI brain scans and sleep tracking to see if light therapy changes how your brain clears toxins during sleep.
Portland, OregonAges 18–89 - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07602283Recruiting
Music to Help with Pain and Memory Problems
This study tests whether listening to music can help reduce pain and improve thinking in people with early memory loss or mild dementia. Researchers will monitor brain activity, heart rate, and pain levels while you or your loved one participate in music sessions.
New Haven, ConnecticutAges 50–80 - NCT07600840Enrolling by invitation
Smart Watch and App for Understanding and Treating Sleep Problems
This study tests a combination of a wearable smart watch, brain-wave monitor (EEG), and smartphone app designed to help understand your sleep problems and emotions. The goal is to develop a digital tool that tracks your sleep patterns and mood to improve insomnia treatment.
Taipei, TaipeiAges 18–64 - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.