Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07385638RecruitingPhase 2
Olorofim for early Valley fever meningitis
This trial tests a new drug called olorofim for people recently diagnosed with coccidioidomycosis (Valley fever) meningitis, a serious fungal infection of the brain lining. It aims to see if the drug is safe and effective as an early treatment.
Tucson, ArizonaAges 18 years+ - NCT06862960RecruitingPhase 2
Ozanimod for moderate Alzheimer's disease
This trial tests whether a daily pill called ozanimod can help people with moderate Alzheimer's disease. The study monitors changes in thinking and memory over time and requires a study partner who can join visits.
Fuzhou, FujianAges 55–80 - NCT07224373RecruitingPhase 1
A study of AZD0120 for multiple sclerosis
This trial tests an experimental drug called AZD0120 in adults with multiple sclerosis. It is designed for people with relapsing or progressive forms of MS who have not responded well to other treatments or have active disease.
Tucson, ArizonaAges 18–60 - NCT06735820RecruitingPhase 1/Phase 2
MEK and MDM2 inhibitors for NF1-related tumors
This trial tests two targeted drugs (selumetinib and milademetan) for people with neurofibromatosis type 1 (NF1) who have either a malignant peripheral nerve sheath tumor (MPNST) or an atypical neurofibromatous neoplasm with uncertain biologic potential (ANNUBP). The goal is to see if blocking certain proteins can shrink or control these tumors.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06666322RecruitingPhase 2/Phase 3
Treating cryptococcal meningitis in people with HIV
This trial is testing new treatments for cryptococcal meningitis, a serious brain infection, in people living with HIV. It aims to find the best way to treat this infection with fewer side effects.
KampalaAges 18 years+ - NCT06511011RecruitingPhase 2
Chinese Herbal Medicine for Chronic Insomnia
This trial tests a Chinese medicine treatment for people with long-term insomnia that is caused by a specific imbalance (Yin deficiency with internal heat). It aims to see if the herbal formula can improve sleep quality and daily function.
ShatinAges 18–65 - NCT07715721Recruiting
Acupuncture and Traditional Chinese Medicine for Sarcopenia and Sleep Problems in Older Adults
This study looks at how Traditional Chinese Medicine body types and sleep patterns relate to muscle loss (sarcopenia) in older adults, and tests whether acupoint stimulation (like acupuncture without needles) can help.
TainanAges 20 years+ - NCT07635563RecruitingPhase 2
Sleep Apnea Treatment with Dronabinol and Acetazolamide
This study tests a combination medication (dronabinol and acetazolamide) to treat obstructive sleep apnea in people who cannot tolerate or use CPAP machines. The goal is to find the right dose that safely reduces breathing interruptions during sleep.
Chula Vista, CaliforniaAges 18–65 - NCT07684183Enrolling by invitation
Eye and Neck Exercises for Text Neck Pain
This study tests if simple eye and neck exercises can reduce pain and improve posture in people with "text neck" (neck pain from looking at screens). It compares eye exercises plus neck stabilization exercises to neck exercises alone.
Lahore, Punjab ProvinceAges 25–50 - NCT07551141Recruiting
Vibration to Help Stroke Recovery: Balance and Walking
This study tests whether vibrations applied to the bottom of your feet can help improve walking and balance after stroke. You'll receive plantar vibration therapy (gentle vibrations under your feet) while performing walking and balance exercises to see if it helps your recovery.
Bolu, MerkezAges 18–75 - NCT07441122Recruiting
Brain game for focus: Using brain-computer tech in older adults
This study tests if a brain-computer interface can help older adults improve attention. You'll use a computer that reads your brain signals and gives feedback to train your focus.
Austin, TexasAges 18–90 - NCT06398847Recruiting
Virtual reality self-hypnosis for HIV-related pain
This study tests if using a virtual reality (VR) headset for self-hypnosis can help people with HIV manage chronic pain. You would practice at home with a smartphone app, and researchers will track your pain levels over time.
New York, New YorkAges 18 years+ - NCT06415344Enrolling by invitationPhase 3
Long-term extension of GTX-102 in Angelman syndrome
This study is a long-term follow-up for people with Angelman syndrome who have already taken part in a GTX-102 trial. It tests whether the treatment continues to be safe and helpful over a longer period.
Los Angeles, CaliforniaAges Any age - NCT07724587Recruiting
Exercise study for muscle wasting in dialysis patients
This trial tests if a supervised exercise program can help people on dialysis who have muscle wasting (uremic sarcopenia). It aims to improve muscle strength, physical function, and quality of life.
NingboAges 18–80 - NCT07724925Recruiting
Comparing two arm therapies for stroke recovery
This study compares two types of arm and hand therapy for people recovering from a stroke. It aims to see which approach helps improve arm function and daily living skills.
Nankana SahibAges 45–70 - NCT07726043Recruiting
Rehab with vibration therapy for balance in CMT1A
This trial tests whether adding a special vibration device to an intensive rehab program helps improve balance in people with Charcot-Marie-Tooth disease type 1A. If you are between 18 and 65 and have mild to moderate leg weakness, you may be able to join.
MarseilleAges 18–65 - NCT07725003Recruiting
Home-based rehab program vs. standard physical therapy for stroke recovery
This study compares a home-based motor relearning program with standard physical therapy delivered through video calls, to see which helps stroke survivors improve movement and function better. It may be a good option if you had a stroke 3 to 12 months ago and have access to a device with internet.
Faisalabad, Punjab ProvinceAges 40–70 - NCT07725601Recruiting
VNS dosing algorithm for epilepsy
This trial tests a new way to adjust the settings on a Vagus Nerve Stimulator (VNS) to better control seizures in people with epilepsy. It is for those who are already getting a VNS implanted to treat their seizures.
Augusta, GeorgiaAges 18–75 - NCT07726758Recruiting
Squat exercise for pre-sarcopenia in older adults
This study tests if doing squat exercises can help improve muscle strength and function in older adults with early muscle loss (pre-sarcopenia). It is for people 65 and older living in Hualien.
TaipeiAges 65–100 - NCT07725471Recruiting
Comparing breathing and neck release in stroke recovery
This study compares two gentle therapy techniques—special breathing exercises and a hands-on release at the base of the skull—to see which helps stroke survivors with one-sided weakness regain movement and breathing. It may be a good fit if you're still recovering from a first stroke months ago and don't have major heart or lung problems.
AfyonkarahisarAges 18–84 - NCT07726563Recruiting
Plasmapheresis for ALS with NRIP2 antibody
This trial tests whether a blood filtering treatment called plasmapheresis can help people with ALS who have a specific antibody (NRIP2) in their blood. It aims to see if removing this antibody can slow the disease and improve symptoms.
Taipei City, TaipeiAges 20 years+ - NCT07726823Recruiting
Two types of manual therapy for leg pain from a bulging disc
This study compares two gentle, hands-on physical therapy techniques to see which better relieves leg pain from a bulging lower back disc. Participants will receive one of the two treatments over several sessions.
Lahore, Punjab ProvinceAges 20–40 - NCT07726017Recruiting
Balance and walking exercises for chronic stroke recovery
This study compares two types of walking and balance exercises for people who had a stroke 6 to 12 months ago. It aims to see which type of practice helps improve balance and walking best.
SialkotAges 40–70 - NCT07181837RecruitingPhase 1/Phase 2
Testing MVX-220 for Angelman Syndrome
This study tests an experimental medicine called MVX-220 to see if it is safe and effective for people with Angelman Syndrome. It includes both children (ages 4-8) and adults (ages 18-50) who can walk independently and have stable seizure medications.
Los Angeles, CaliforniaAges 4–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.