Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+ - NCT07598487Enrolling by invitation
Physical Therapy Techniques for Stroke Recovery and Balance
This study compares two types of physical therapy to help people regain trunk control and balance after a stroke. Participants will receive either PNF (a hands-on technique using rhythmic movements) or NDT (another hands-on technique focusing on movement patterns) to improve stability.
Faisalabad, Punjab ProvinceAges 40–65 - NCT07595068Recruiting
Ultrasound for Sleep and Heart Function Before Heart Surgery
This trial tests a new treatment using focused ultrasound to help regulate your nervous system and improve sleep quality before heart surgery. The goal is to help reduce anxiety and improve how well you sleep during the time leading up to and after your cardiology procedure.
Huangshi, HubeiAges 18–79 - NCT07598617Recruiting
Testing a New Computer Memory Assessment for Early Cognitive Changes
This study evaluates a new computer-based test to detect early memory and thinking changes before they progress to dementia. Researchers are looking for adults 65+ who've noticed subtle cognitive changes in the last 5 years to help refine and test this assessment tool.
Plymouth, DevonAges 65 years+ - NCT07603583Recruiting
Heart Rate Variability to Detect Sleep Apnea in Hypertension
This study tests whether a simple heart-rate measurement can help detect obstructive sleep apnea (a breathing condition during sleep) in people with high blood pressure. The goal is to find an easier way to screen for sleep apnea, which often goes undiagnosed but can worsen heart health.
Kaohsiung City, KaohsiungAges 18–65 - NCT07596030Recruiting
Self-applied ear stimulation for nerve pain after chemo
This trial tests a small device you wear on your ear to see if it can reduce nerve pain caused by chemotherapy (CIPN). You use it yourself at home, and it may help with the tingling, numbness, or burning in your hands and feet.
Coral Gables, FloridaAges 18–80 - NCT07602283Recruiting
Music to Help with Pain and Memory Problems
This study tests whether listening to music can help reduce pain and improve thinking in people with early memory loss or mild dementia. Researchers will monitor brain activity, heart rate, and pain levels while you or your loved one participate in music sessions.
New Haven, ConnecticutAges 50–80 - NCT07595783Recruiting
Brain Training for Children With ADHD Using Neurofeedback
This study tests a new type of brain training called neurofeedback to help children with ADHD. Children complete sessions where they learn to control their own brain activity, which may improve attention and focus.
BielefeldAges 6–13 - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07598643RecruitingPhase 2
Study of tofacitinib for immune function in Down syndrome
This study tests if an oral medication called tofacitinib can help the immune system work better in children and young adults with Down syndrome, which may improve learning and development. The study will follow participants for 6 months.
Aurora, ColoradoAges 6–22 - NCT07599696Recruiting
Speech Amplification Devices for Parkinson Disease
This research study tests special amplification devices designed to help people with Parkinson disease or related conditions speak more clearly. The goal is to improve how well others can understand your speech.
East Lansing, MichiganAges 50 years+ - NCT07600840Enrolling by invitation
Smart Watch and App for Understanding and Treating Sleep Problems
This study tests a combination of a wearable smart watch, brain-wave monitor (EEG), and smartphone app designed to help understand your sleep problems and emotions. The goal is to develop a digital tool that tracks your sleep patterns and mood to improve insomnia treatment.
Taipei, TaipeiAges 18–64 - NCT07598695RecruitingEarly Phase 1
Hand Sensory Feedback and Movement Recovery After Stroke
This early-stage study tests whether special sensory feedback (like touch or vibration on your hand) can help improve hand movement and coordination in people recovering from stroke. Researchers want to understand how the brain relearns hand control.
Washington D.C., District of ColumbiaAges 20–70 - NCT07599150Recruiting
Brain mapping study for epilepsy and breathing patterns
This research studies how the brain controls breathing in people with drug-resistant epilepsy. Researchers use special electrodes placed in your brain during surgery to map these connections and better understand seizures.
Bron, RhoneAges 18–55 - NCT07598435Recruiting
Arm Recovery Exercises After Stroke: Two Training Methods Compared
This study tests two different physical therapy approaches to help improve arm movement and function in people recovering from stroke. You'll participate in therapy sessions using either rhythmic initiation (guided movement exercises) or isometric training (muscle-tightening exercises) to see which helps your arm recover better.
Faisalābad, Punjab ProvinceAges 40–60 - NCT06629389RecruitingPhase 2
Cannabidiol (Kanbis) for Parkinson's symptoms
This trial tests whether cannabidiol (CBD) can help with Parkinson's disease symptoms. Researchers want to see if it's safe and effective for people with mild to moderate Parkinson's who are already on stable medications.
Mendoza, Mendoza ProvinceAges 40–80 - NCT03749538Recruiting
Brain stimulation test for autoimmune muscle weakness
This trial tests whether a noninvasive brain stimulation technique (through the scalp) can improve muscle weakness in people with certain autoimmune muscle diseases. It may help by changing brain signals that affect how muscles work.
São PauloAges 18–80 - NCT03092180Recruiting
Tests a treatment approach for certain muscle inflammation diseases
This trial looks at treatment strategies for people with idiopathic inflammatory myopathies, which are illnesses where the immune system attacks muscles. It may help improve how treatment is chosen and optimized for this group of conditions, but it specifically excludes several related muscle diseases.
São PauloAges 18 years+ - NCT05231876Recruiting
French Wilson disease registry
This study keeps a registry (a confidential list) of people with Wilson disease. It helps researchers learn more about the disease and improve future care, without requiring specific treatment changes.
Paris, Île-de-France RegionAges birth–99 years - NCT05345483Recruiting
Rescue stent after failed clot removal in brain arteries
This trial looks at using a special stent device to reopen a blocked brain artery when a standard clot-removal procedure did not work. It may help restore blood flow and reduce damage, especially when the stroke area on scans is small enough and the symptoms started within 24 hours.
AschaffenburgAges 18 years+ - NCT05920174Recruiting
Implant test to help movement in people with severe paralysis
This trial studies whether an implanted device that can record and stimulate brain signals is safe and may improve movement in people with motor disability from certain nerve or brain conditions. It’s for adults with stable, long-lasting paralysis and good brain function who can follow the study plan.
Beijing, Beijing MunicipalityAges 18–80 - NCT06167330Recruiting
Titan trial: Reducing phantom limb pain
This trial tests a new method to reduce phantom limb pain (pain felt in a missing limb) using gentle electrical stimulation and simple mental exercises. It is for people with one-sided amputations who have had phantom limb pain for at least three months and still have pain episodes now.
Randwick, New South WalesAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.