Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07721688Recruiting
Different frequency brain stimulation for Parkinson's disease
This study tests a new, noninvasive brain stimulation technique (called temporal interference stimulation) given at different frequencies. It aims to improve Parkinson's symptoms by gently stimulating the brain area involved in movement.
Guangzhou, GuangdongAges Any age - NCT07724171Recruiting
Long-term results after PFO closure surgery
This study looks at how well patients do over time after having a hole in their heart (patent foramen ovale, or PFO) closed with a small device inserted through a vein. It may help doctors understand the benefits and risks of the procedure.
SeoulAges 19 years+ - NCT07721701Recruiting
Digital Dementia Registry for Bavaria
This study follows people with mild cognitive impairment or dementia and their family caregivers over time. It aims to learn more about how these conditions progress and how to improve care, especially for those living in Bavaria.
AschaffenburgAges Any age - NCT07722429Recruiting
Personalized spinal stimulation for arm function after spinal injury
This study tests a personalized electrical stimulation treatment placed near the spine to see if it can improve arm and hand function after a spinal cord injury. If you have a stable injury above the mid-back and have not had new nerve problems in the last 6 months, you may be able to join.
Hualien CityAges 18–70 - NCT07722130Recruiting
Spinal cord stimulation to help breathing after neck injury
This trial tests if a device placed near the spinal cord can help people with a neck injury breathe better without a ventilator. It's for those who still need breathing support at least 2 weeks after their injury.
Nanjing, JiangsuAges 18–75 - NCT07723313RecruitingEarly Phase 1
Amniotic membrane and secretome for carpal tunnel release
This trial tests whether adding a special membrane (amniotic membrane) and a natural healing fluid (secretome) to standard carpal tunnel release surgery can improve hand function better than surgery alone. It may be a good option if your wrist pain and numbness haven't gone away with other treatments.
Denpasar, BaliAges 18 years+ - NCT07324837RecruitingPhase 3
Study of a clot-busting drug for stroke up to 24 hours later
This trial tests a single dose of a new clot-dissolving medicine for people who had a stroke 4.5 to 24 hours ago. It may help if you cannot have standard treatments like a clot-removal procedure or other clot-busting drugs.
Ryazan, Ryazan OblastAges 18 years+ - NCT07448103Recruiting
Robot-assisted rehab for kids with brain injury
This trial uses a social robot and artificial intelligence to help children with acquired brain injury do rehabilitation exercises at the hospital or at home. The robot guides them through arm and hand activities to improve movement and recovery.
Madrid, MadridAges 7–16 - NCT07246980Recruiting
Allay hydrogel cap safety monitoring study
This study monitors patients who receive the Allay hydrogel cap to check its safety and how well it works. It helps doctors learn more about this treatment.
Orlando, FloridaAges Any age - NCT07142291RecruitingPhase 2
Cromolyn inhaler for early ALS
This trial tests if an inhaled drug called cromolyn can help people with early-stage ALS. It is for people who can still breathe well and are not yet using a ventilator.
Scottsdale, ArizonaAges 18–75 - NCT07711457Recruiting
Extended reality to guide brain bypass surgery
This trial tests whether extended reality (XR) technology can help surgeons more precisely plan and perform bypass surgery for people with moyamoya disease or blocked carotid arteries. It may make the procedure safer and more effective.
TaipeiAges 18–85 - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT06729632Recruiting
Cooling device to protect ears from noise damage
This trial tests a non-invasive device that cools the ears to prevent hearing loss from loud noise. It is for adults aged 18-55 with normal hearing who are at risk for noise-induced hearing loss, such as firefighters.
Miami, FloridaAges 18–55 - NCT07483255Recruiting
Fetal embolization trial for vein of Galen malformation
This trial tests a fetal procedure to treat a rare brain blood vessel condition called vein of Galen malformation. The goal is to improve the baby's outcome by closing off abnormal connections inside the brain before birth.
Boston, MassachusettsAges 18 years+ - NCT06404268RecruitingPhase 1/Phase 2
Helping stroke survivors regain ankle movement with exercise
This study tests whether gentle leg exercises can help people recovering from a recent stroke. The focus is on improving ankle movement and strength on the weak side.
Baltimore, MarylandAges 30–85 - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT07655531Recruiting
Yogic breathing and meditation for spinal cord conditions
This study tests whether a simple yogic breathing and meditation program, done over video calls, can help people with spinal cord conditions feel better and manage symptoms. You can join from home with just an internet connection.
Birmingham, AlabamaAges 18–89 - NCT07245706Recruiting
Shoulder Health After Rehab and Performance Training
This study looks at how shoulder health changes after a rehabilitation and performance training program for people with paraplegia who use manual wheelchairs. It may help you strengthen your shoulders and prevent injuries as you start your life after rehab.
Nottwil, Canton of LucerneAges 18–70 - NCT06375278Recruiting
Cooling device to protect hearing during cochlear implant
This trial tests a special cooling device used during cochlear implant surgery to help protect any remaining hearing you have. It may be a good option if you are already planning to get a cochlear implant at the University of Miami.
Miami, FloridaAges 18 years+ - NCT07137637RecruitingPhase 1
HPB-092 for relapsed or refractory AML
This trial tests a new drug, HPB-092, in adults with acute myeloid leukemia that has come back or not responded to treatment. The goal is to see if it can help when other treatments have not worked.
TianjinAges 18 years+ - NCT07537075Enrolling by invitationPhase 2/Phase 3
Continuing SKY-0515 treatment for Huntington's disease
This is a follow-up study for people with Huntington's disease who already completed an earlier SKY-0515 trial and tolerated it well. Researchers want to see how safe and effective the drug continues to be with longer-term use.
New Lambton Heights, New South WalesAges 25 years+ - NCT07114458Recruiting
Delirium and Thinking Changes in Older Hospital Patients in Isolation
This study looks at how being in isolation in the hospital might affect confusion or thinking problems in older adults. You may be eligible if you are 70 or older and have been in isolation for at least 24 hours.
Hamburg, Free and Hanseatic City of HamburgAges 70 years+ - NCT04789148RecruitingPhase 1
Nasal oxytocin trial for people with hormone deficiency
This early-phase study tests whether a spray of oxytocin in the nose can be given safely and may affect symptoms in people with arginine-vasopressin deficiency. You might qualify if your hormone levels are stable and you can safely take the nasal study medicine during the study period.
Boston, MassachusettsAges 18 years+ - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.