Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03535142Recruiting
Fatty liver in people considering bariatric surgery
This study looks at how fatty liver disease may predict future liver health in people with severe weight gain. It compares people who are planning bariatric (weight-loss) surgery with similar people who are not, to better understand who may be at higher risk.
EsbjergAges 18 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT03546309Recruiting
Testing RIC to help children with moyamoya after surgery
This trial studies whether a treatment called RIC (remote ischemic conditioning) is safe and helpful for children with moyamoya disease who undergo revascularization surgery. It aims to improve outcomes after surgery and reduce risk, while carefully tracking safety.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT03550391RecruitingPhase 3
Surgery-like brain radiation vs avoiding the memory center
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
Tucson, ArizonaAges 18 years+ - NCT03552926Recruiting
Biobank and scan database for recent small stroke patients
This study builds a database and collection (a biobank) from people who recently had a small stroke affecting deep brain areas. It may help researchers better understand small stroke patterns and support future care through better brain imaging and follow-up.
ParisAges 18 years+ - NCT03559114RecruitingPhase 3
Preventing blood clots after severe brain injury
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Calgary, AlbertaAges 18 years+ - NCT03563729RecruitingPhase 2
Melanoma in the brain: steroids plus targeted therapy
This Phase 2 trial studies how giving steroid medicine for brain swelling may help people with melanoma that has spread to the brain, and whether adding a targeted approach works for a specific genetic tumor type. It may help shrink brain tumors and improve symptoms, while comparing how patients respond.
Herlev, Capital RegionAges 18 years+ - NCT03560388Recruiting
Acupuncture and integrative care after gynecologic cancer surgery
This trial studies whether acupuncture and supportive “integrative care” can help people around the time of gynecologic cancer surgery. You may be invited to participate if you’re having surgery for suspected or confirmed gynecologic cancer and can safely take part in the study.
HaifaAges 18 years+ - NCT03564561Recruiting
Pompe disease study of walking and symptoms over time
This study follows people with Pompe disease to better understand how the disease progresses and how walking function changes. You may help researchers learn what symptoms and test results matter most, without necessarily receiving a new treatment.
Garches, Hauts-de-SeineAges 18–80 - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03570450RecruitingPhase 1
Stem cell treatment for non-lacunar stroke after the first day
This early-phase study tests a stem cell treatment for certain types of stroke, focusing first on safety and the right dose. It may help doctors learn whether the treatment is safe and potentially beneficial when given soon after stroke begins.
GrenobleAges 18 years+ - NCT03571763Recruiting
Anti-clotting treatment study in stroke patients with small brain bleeds
This trial looks at how anti-clotting medicines affect small blood vessel bleeds in the brain (cerebral microbleeds) and larger bleeding in the skull after an ischemic stroke. It may help doctors choose safer prevention medicines for people who already have these small bleeds seen on brain MRI.
ShenyangAges 18 years+ - NCT03574207Recruiting
Brain stimulation study for memory in certain adults
This study tests a targeted, non-surgical brain stimulation method to help people with memory, especially remembering facts over time. It compares healthy adults and adults with amnestic mild cognitive impairment (aMCI), using sessions plus brain scans and memory testing.
Omaha, NebraskaAges 19 years+ - NCT03578003Recruiting
Bright morning light to improve sleep in veterans
This study tests whether using bright morning light can improve sleep quality in veterans. You may be able to join if you’re not already using a light box and you don’t have certain eye or mood conditions.
Portand, OregonAges 18 years+ - NCT03582293RecruitingPhase 3
Tranexamic acid to prevent worsening chronic brain bleed
This Phase 3 study tests whether tranexamic acid (a medicine that helps blood clot) can stop a chronic subdural hematoma from getting worse. It’s for people diagnosed by CT who are being treated without surgery at first.
AmsterdamAges 50 years+ - NCT03584204Recruiting
Imaging study for people with liver cirrhosis
This study looks at how liver cirrhosis shows up on non-invasive imaging like CT scans, and how those findings relate to outcomes. It may help researchers better understand what scan patterns could signal disease severity.
BonnAges 18–80 - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT03592563Recruiting
Brain health follow-up study for adults
This study follows adults over time to better understand brain health and brain-related conditions. You may join if you already have certain neurological or psychiatric diagnoses, are at higher risk, or simply want to help research on maintaining brain health.
Hong KongAges 18 years+ - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT03601702Recruiting
EmboTrap device for large stroke blockages
This trial studies whether a specific clot-removal device (EmboTrap II) works well for acute stroke caused by a large artery blockage. It may help restore blood flow faster in people who have certain scan patterns and can be treated within 12 hours.
MilanAges 18 years+ - NCT03612193Recruiting
Study how gut bacteria relates to complex regional pain
This study looks at differences in gut bacteria (from a stool sample) in people with complex regional pain syndrome (CRPS) and in people who live with them. The goal is to understand whether gut microbes might play a role in CRPS and improve understanding of the condition.
St Louis, MissouriAges 18 years+ - NCT03607565Recruiting
Imaging test to measure brain blood flow in stroke
This trial studies a new imaging measurement derived from DSA (a special type of brain blood-vessel scan) to better estimate how well blood is flowing in the brain. It may help doctors assess stroke-related blood-flow problems, but it excludes people who have brain bleeding.
Xi'an, ShaanxiAges Any age - NCT03610763Recruiting
Training brain recovery after arm nerve repair
This study tests a way to help your brain and nerves work better after an arm/hand nerve repair that is already in the long-term (chronic) recovery stage. It may help improve hand and arm function by targeting “neuroplasticity,” meaning the brain’s ability to adapt after injury.
Louisville, KentuckyAges 18 years+ - NCT03611816Recruiting
Biobank study for atrial fibrillation and stroke samples
This study collects and stores medical information and biological samples from people with atrial fibrillation (or certain types of stroke). It helps researchers better understand these conditions and may support future improvements in diagnosis or treatment.
Bourg-en-BresseAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.