Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT06714565Recruiting
Can blood pressure and brain oxygen predict falls?
This study looks at how measuring blood pressure and oxygen levels in the brain may help predict falls in older adults. If you have fallen before, your participation could help doctors find better ways to prevent future falls.
AmsterdamAges 65 years+ - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT06742580Recruiting
Sudden facial paralysis and homocysteine study
This study looks at a possible link between a substance in the blood called homocysteine and sudden facial paralysis (Bell's palsy). If you've recently been diagnosed with this condition, you may be able to join.
AfyonkarahisarAges 18–80 - NCT06663631RecruitingPhase 1
Hibernation-like therapy for stroke recovery after clot removal
This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.
Linyi, ShandongAges 18–80 - NCT07549048Recruiting
Understanding caregiver stress in multiple sclerosis
This study asks patients with MS and their family caregivers about the emotional and physical strain of caregiving. By understanding caregiver burden, researchers hope to develop better support systems for families managing MS.
Istanbul, BahcelievlerAges 18–80 - NCT06271018Recruiting
Tocilizumab for Aortitis in Giant Cell Arteritis
This trial tests the drug tocilizumab (Actemra) to see if it helps reduce swelling in the aorta in people with giant cell arteritis (GCA) who are newly diagnosed or have had a flare. It may offer a targeted treatment for aortitis without using high-dose steroids.
ParisAges 18 years+ - NCT07548944Recruiting
How Electrical Stimulation Affects Your Vision
This study watches how a treatment called transcorneal electrical stimulation (TES)—which uses gentle electrical pulses on your eye—affects your vision in the short term. You'll be observed while using the OkuStim device, and researchers will ask about any improvements you notice in your sight.
Frankfurt am MainAges 18 years+ - NCT07546942Enrolling by invitationPhase 1/Phase 2
Autism Treatment Using Stem Cells, Gut Microbiome, and Diet
This study tests whether a combination of stem cell therapy, gut microbiome restoration (using specially prepared stool), and dietary changes can improve autism symptoms, communication, social behavior, and digestive issues. Researchers believe gut health and immune system problems may contribute to autism, and this trial explores whether treating these areas helps.
Hamilton, MontanaAges 10–90 - NCT07543302Enrolling by invitation
Can Ear Nerve Stimulation Reduce Inflammation in Duchenne Muscular Dystrophy?
This trial tests whether gently stimulating a nerve in the ear can lower inflammation levels in boys with Duchenne muscular dystrophy (DMD). The goal is to see if this non-invasive approach might help slow disease progression or ease symptoms.
StockholmAges 5–17 - NCT07543367Recruiting
Brain implant to restore arm movement in ALS
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
Jacksonville, FloridaAges 22 years+ - NCT06091332RecruitingPhase 2
Sirolimus for brainstem cavernoma bleeding
This trial tests if sirolimus, a medicine that may help reduce abnormal blood vessels, can prevent another brain bleed in people who recently had a bleed from a brainstem cavernoma. You would receive either sirolimus or a placebo to see if it works.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06074614Recruiting
Breathing and brain control in Parkinson's disease
This study looks at how the brain controls breathing in people with Parkinson's disease compared to healthy volunteers. It may help us understand breathing problems that can occur in Parkinson's.
Nijmegen, GelderlandAges 18 years+ - NCT06361238RecruitingPhase 3
Liraglutide to prevent confusion after heart surgery in seniors with diabetes
This trial is testing if liraglutide, a diabetes medication, can prevent delirium (sudden confusion) in older adults with type 2 diabetes who are having planned heart surgery. If you qualify, you may help find a new way to protect brain function after surgery.
Nanjing, JiangsuAges 60 years+ - NCT06490822Recruiting
Skin study for frontotemporal lobe degeneration
This study looks at whether skin samples can help detect brain changes in people with frontotemporal lobe degeneration (a type of dementia) and related conditions. It compares skin from patients and healthy volunteers to find clues that might help with diagnosis.
NantesAges 50–75 - NCT06715436Recruiting
Ketogenic diet for multiple sclerosis
This study tests whether a ketogenic diet can help people with multiple sclerosis. You would follow a special high-fat, low-carb diet for a period, and the researchers will check its effects on your symptoms and overall health.
PaviaAges 18–60 - NCT07546708Recruiting
Understanding Dementia Care in Black Immigrant Communities
This study explores how dementia (memory loss) affects Black immigrant families and their caregivers. Researchers want to learn about challenges and support needs to improve care and services for Black immigrant communities.
Minneapolis, MinnesotaAges 18 years+ - NCT07546786Recruiting
How Meditation Affects Thinking and Emotions
This study compares how meditation affects brain function and emotional regulation in people who meditate regularly versus those who don't. Researchers want to understand if regular meditation improves focus, memory, and emotional well-being.
Boston, MassachusettsAges 18 years+ - NCT07544082Recruiting
Acupuncture for Insomnia Related to Heart-Spleen Imbalance
This study tests whether acupuncture using traditional five-point techniques can help people with long-term insomnia, especially those experiencing poor sleep quality, nightmares, and early morning awakening. It focuses on a specific pattern in traditional Chinese medicine called Heart-Spleen deficiency.
Ho Chi Minh CityAges 18 years+ - NCT07544875Recruiting
Brain Training Program for Adults in Hong Kong
This volunteer training program in Hong Kong teaches brain exercises and cognitive skills to adults age 50 and older. The program aims to help keep your mind sharp and may improve memory and thinking abilities.
Hong KongAges 50 years+ - NCT07548801Enrolling by invitation
Brain Stimulation for Parkinson's Disease Movement
This study tests whether a non-invasive brain stimulation technique applied to the back of your brain (cerebellum) can help improve movement and balance in people with mild to moderate Parkinson's disease. The treatment uses a small electrical current to stimulate brain activity.
BrusselsAges 18 years+ - NCT07546539Recruiting
Light Therapy for Chronic Fatigue Syndrome
This study tests whether a special type of light therapy (called photobiomodulation) can reduce severe tiredness in people with chronic fatigue syndrome. The light is applied to the skin and may help boost energy levels and improve daily function.
Larkana, SindhAges 18–60 - NCT07543991RecruitingPhase 1
Gene therapy for giant axonal neuropathy via vagus nerve
This is a follow-up study for patients who previously received an experimental gene therapy (scAAV9/JeT-GAN) for giant axonal neuropathy (GAN), a rare genetic nerve disorder. The new treatment delivers the therapy directly into the vagus nerve—a major nerve in the neck—to help manage nerve damage and related symptoms.
Dallas, TexasAges 10–25 - NCT07548580Recruiting
Early Movement Therapy for Brain Injury in Hospital ICU
This study looks at how gentle, early physical movement during ICU care affects recovery in patients with serious brain injuries like stroke or head trauma. Researchers will track how patients respond to a structured movement program while they're on a breathing machine.
CopenhagenAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.