Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03614962Recruiting
Warmth and TENS to improve thinking in dementia
This study tests whether using a warmth treatment and a gentle electrical nerve-stimulation device (TENS) can improve thinking and memory in people with mild to moderate dementia. It may help by supporting brain and nerve function, alongside your usual care.
Hong KongAges 65 years+ - NCT03621254Recruiting
Finding the best FES training plan after spinal cord injury
This trial studies which kind of electrical muscle stimulation (FES) exercise training works best for people after a spinal cord injury. It may help improve leg muscle activation and training after SCI by comparing different training approaches.
Nottwil, Canton of LucerneAges 18–75 - NCT03621566Recruiting
Sleep apnea registry for adults with non-obstructive events
This study builds a registry to learn more about sleep apnea patterns, especially cases where most breathing events are not caused by blocked airway tissue. You may be able to join if you’re an adult with a specific sleep test result.
AalstAges 18 years+ - NCT03621839Recruiting
Study of new spinal-fluid tests for Alzheimer’s disease
This study looks at new test markers found in spinal fluid to help with diagnosing Alzheimer’s disease. If you are already getting a spinal-fluid sample as part of your dementia workup, this trial may check it for additional information.
Nancy, Grand EstAges Any age - NCT03624374Recruiting
Study of LBSL in people with DARS2 mutations
This trial is a natural history study, meaning it tracks how LBSL (a genetic condition) affects the brain, brainstem, and spinal cord over time. It may help researchers better understand disease patterns and provide information that could support future treatments.
Baltimore, MarylandAges Any age - NCT03622879Recruiting
Mirror therapy plus mild skin stimulation for leg movement after stroke
This trial tests whether using a mirror together with mild electrical stimulation on the skin can improve lower-limb movement after stroke. You may be eligible if you can already lift your ankle a bit and walk independently, and if certain thinking, vision, and skin issues are not present.
Hong KongAges 55–85 - NCT03631953RecruitingPhase 1
Test alpelisib plus trametinib for hard-to-treat meningiomas
This Phase 1 trial studies whether combining two targeted medicines—alpelisib and trametinib—can shrink or slow progressive meningiomas that have already been treated with standard surgery and radiation. If you qualify, you may help test a new treatment approach for tumors that keep growing.
MarseilleAges 18 years+ - NCT03638505Recruiting
Quality of life study for people with PSP and their caregivers
This study looks at quality of life for people with progressive supranuclear palsy (PSP) and the day-to-day burden on the caregiver. It may help researchers understand what support needs are most important and how caregiving affects wellbeing.
Marseille, PACAAges 18 years+ - NCT03638583Recruiting
Online testing study to prevent or spot Alzheimer’s early
This study invites people age 50+ who do not have dementia to do ongoing thinking tests online. If an online risk screen suggests you may be at higher risk, you may be referred for in-person body tests (biomarker assessment).
San Diego, CaliforniaAges 50–85 - NCT03642028RecruitingPhase 4
Sleep medicine study for PTSD-related sleep problems
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
Long Beach, CaliforniaAges 18–75 - NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT03644732Recruiting
Study of brain activity during epilepsy testing using SEEG
This study maps how thinking and memory work by recording brain signals during a presurgical epilepsy workup. It may help doctors better understand drug-resistant focal epilepsy and improve how they plan treatment.
GrenobleAges 18–65 - NCT03646214Recruiting
Oral appliance to improve snoring and sleep in pregnancy
This trial tests an oral device worn during sleep to improve sleep quality for pregnant adults who snore. You may qualify if you meet specific dental and airway (throat/mouth) checks and can use the study sleep recorder and device.
Dallas, TexasAges 18–45 - NCT03649503Recruiting
Parkinsonian disorders registry in China
This study is a real-world registry that collects information from people living with Parkinsonian disorders in China. It may help researchers better understand how these conditions affect patients day to day.
Shanghai, Shanghai MunicipalityAges Any age - NCT03649698Recruiting
Exercise and nutrition plan for loss of muscle with aging
This trial studies whether a structured exercise and nutrition program can improve muscle health in older adults with (pre)sarcopenia, especially those who may have slower walking or reduced strength. It also checks safety by excluding people with unstable health problems and several specific medical conditions.
Leuven, Vlaams-BrabantAges 65 years+ - NCT03649880RecruitingPhase 2
Testing a special PET scan for brain tumor activity
This trial studies whether a brain PET scan using a medicine called FMISO can help show how active certain brain tumors are. It mainly aims to see if the scan is practical and useful in planning care for people with suspected or known brain tumors.
Portland, OregonAges 18 years+ - NCT03653156Recruiting
Aging and brain study for mild memory loss and dementia
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Hefei, AnhuiAges 18 years+ - NCT03657732Recruiting
Study of inherited Alzheimer’s genes in families
This study looks at people from families with inherited Alzheimer’s disease, including those who may be cognitively normal. It uses medical checkups and brain/nerve tests to better understand Alzheimer’s risk and symptoms in families with specific gene changes.
Hefei, AnhuiAges 18 years+ - NCT03655912Recruiting
Video games and eye therapy for lazy eye
This study tests whether binocular (two-eye) visual therapy using video games can improve “lazy eye” vision. It’s aimed at people with certain types of lazy eye and who have not had previous amblyopia treatment.
Monterrey, Nuevo LeónAges 4–10 - NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT03665831Recruiting
Deep TMS for depression and memory problems in older adults
This study tests a type of brain stimulation called Deep TMS to help reduce depression and improve or stabilize memory-related symptoms in older adults with Alzheimer’s disease. It’s mainly for people whose depression did not improve or could not be tolerated with antidepressant medicine.
Toronto, OntarioAges 60 years+ - NCT03671889Recruiting
Ultrasound treatment to open the brain barrier for Alzheimer’s
This trial tests a non-surgical ultrasound procedure (called MR-guided focused ultrasound) meant to temporarily “open” the brain’s protective barrier so treatments may work better for Alzheimer’s disease. It also looks at safety and how well people tolerate the procedure and related tests.
Delray Beach, FloridaAges 50–85 - NCT03676868Recruiting
Study of brain blood vessel malformations and outcomes
This study looks at how brain arteriovenous malformations (abnormal connections between arteries and veins in the brain) behave over time, and how different treatment choices affect outcomes. It may help researchers better predict prognosis and guide future care.
ParisAges birth+ - NCT03675087Recruiting
Testing how exercise affects symptoms in ME/CFS
This trial studies how people with ME/CFS respond to an exercise test. It may help researchers understand what kind of exercise response is typical and how it relates to symptoms.
MadridAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.