Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03475147Recruiting
Smartphone test for vision problems
This trial is checking how well a smartphone “flicker” vision test works for people who have a scotoma (an area of missing or reduced vision). It may help confirm whether the smartphone test can measure or detect optic-related vision problems.
Iowa City, IowaAges 18–80 - NCT03475173Recruiting
Non-invasive eye scans for healthy and specific retinal problems
This study tests new, non-invasive ways to measure how the retina (the light-sensing part of the eye) is structured and how well it works. It may help researchers better understand certain vision disorders and how to track them, without surgery or injections.
Iowa City, IowaAges 18–99 - NCT03478852Recruiting
Epilepsy screening and evaluation for people 8 and older
This study checks how people with known or suspected epilepsy are evaluated and followed. It may help by improving screening and understanding care for epilepsy in children and adults.
Bethesda, MarylandAges 8–110 - NCT03481205Recruiting
Air-transport treatment to protect brain tissue after stroke
This trial studies a protective “conditioning” treatment given during air ambulance transport for people with a suspected large-vessel ischemic stroke. The goal is to reduce further brain injury and preserve more brain tissue while you’re being transported for stroke care.
Iowa City, IowaAges 18–80 - NCT03481283Recruiting
Testing amylin’s role in nerve pain from type 2 diabetes
This study looks at whether amylin is involved in nerve damage causing pain or numbness in the feet or hands for people with type 2 diabetes. If you qualify, you may be evaluated with nerve testing to see how your nerve function compares to the study’s targets.
Lexington, KentuckyAges 18 years+ - NCT03485040Recruiting
Rehab study for arm weakness after stroke
This study tests a rehabilitation approach to help people recover arm movement after an ischemic or bleeding stroke. You may be able to join if you’re currently an inpatient in the stroke neurology unit and have arm weakness but are medically stable and able to follow simple instructions.
Boston, MassachusettsAges 18–90 - NCT03492060Recruiting
Study of genetic variants in neurogenetic disorders over time
This study looks at how people’s genetic test results relate to health changes over time in conditions caused by gene differences. If you already have genetic confirmation of a disease-causing variant, you may be able to join.
New York, New YorkAges Any age - NCT03489499Recruiting
Genetic testing study of pain after planned surgery
This study looks at whether genetic differences can help predict how much pain you may have after an elective (planned) operation. If you qualify, you may be asked to give consent and share information so researchers can compare pain experiences across people.
BernAges 18 years+ - NCT03489278Recruiting
Support procedures study for ALS using electronic health records
This study is about improving the research process for people with ALS by using electronic health records from participating clinics. If you have ALS and receive care at an Epic-using center, you may be asked to help with consent and study procedures.
Irvine, CaliforniaAges 18 years+ - NCT03490630Recruiting
Survey study after bariatric weight-loss surgery
This study asks adults to complete patient-reported surveys after elective bariatric (weight-loss) surgery. It may help doctors better understand how patients experience recovery and outcomes.
BernAges 18 years+ - NCT03502408Recruiting
CT or MRI blood-flow imaging in strokes treated within 6–24 hours
This study checks how well CT or MRI “blood-flow” scans predict and measure brain injury in people with an acute ischemic stroke who are getting a clot-removing procedure. It may help doctors choose the right people for treatment and evaluate treatment effects using imaging taken soon after hospital arrival.
Hangzhou, ZhejiangAges 18 years+ - NCT03495440Recruiting
Family skills program for youth with developmental disabilities
This trial studies a parent-and-family intervention designed for families of youth with developmental disabilities. It may help parents and siblings better understand needs and improve day-to-day support at home through guided, theory-based activities and surveys.
Fort Wayne, IndianaAges Any age - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT03503331RecruitingPhase 2
Alzheimer’s imaging add-on for research center patients
This study adds special brain scans (MRI and a PET scan) for people already enrolled in the UAB Alzheimer’s Disease Center research program. The scans are used to learn more about brain changes in Alzheimer’s, which may help researchers find better ways to measure and understand the disease.
Birmingham, AlabamaAges 50 years+ - NCT03508960Recruiting
Parkinson’s disease registry for people with early onset
This study is a registry that collects information from people with Parkinson’s disease (PD) to better understand the condition, especially in people whose symptoms started by age 50. It may help researchers learn which factors matter most for early-onset PD.
Changsha, HunanAges Up to 50 years - NCT03509558Recruiting
Tapping a device on the back plus leg exercise for walking
This study tests whether a device placed on the back can help improve leg movement and walking ability after a spinal cord injury. It combines the device with supervised physical therapy over many weeks to see if it helps with daily mobility.
Seattle, WashingtonAges 21–70 - NCT03509064Recruiting
Study of quality of life in Sjögren nerve pain
This trial looks at people with Sjögren who may have small-fiber nerve problems that can cause pain, temperature-related nerve symptoms, or body-function nerve issues. It aims to understand how these nerve problems affect quality of life and medical needs, and compare them with people without neuropathy.
ParisAges 18 years+ - NCT03508986Recruiting
Parkinson’s family registry for people with Parkinson’s
This trial is a research registry that collects health and family information from people with Parkinson’s disease (and sometimes their close relatives). It may help doctors better understand how Parkinson’s runs in families.
Changsha, HunanAges Any age - NCT03511807Recruiting
Tests sound and mild electrical stimulation for tinnitus relief
This study tests whether adding sound and/or mild electrical stimulation can reduce tinnitus (ringing or other noises in the ear). It is looking for adults who have had tinnitus for at least 6 months and can complete questionnaires about what they feel.
Irvine, CaliforniaAges 18 years+ - NCT03517761Recruiting
Bone marrow injection trial for upper neck ligament injuries
This trial studies whether an injection using bone marrow concentrate can help people with specific upper-neck ligament and joint injuries after a trauma. It aims to improve symptoms and disability so you may be able to avoid or delay surgery.
Broomfield, ColoradoAges 18–65 - NCT03523052Recruiting
People with Parkinson’s and SNCA gene changes
This registry study enrolls people who have Parkinson’s disease and carry certain SNCA gene changes. It aims to better understand how these genetic changes relate to Parkinson’s, which can guide future research and care.
Changsha, HunanAges Any age - NCT03523065Recruiting
Parkinson’s registry for people with GBA gene changes
This registry collects information about people with Parkinson’s who have specific changes in the GBA gene. The goal is to better understand how these gene changes affect Parkinson’s and support future research.
Changsha, HunanAges Any age - NCT03523104Recruiting
Registry for Parkinson’s with LRRK2 gene variants
This study is a registry that collects information from people with Parkinson’s who have specific LRRK2 gene changes. It helps researchers understand how this genetic form of Parkinson’s behaves over time.
Changsha, HunanAges Any age - NCT03526822Recruiting
Study of new glioblastoma using MRI scans and lab markers
This study follows people newly diagnosed with glioblastoma to see how certain lab signals (MMP2 and MMP9) match up with MRI scan features. It may help doctors better understand the disease and how it appears on imaging, but it’s mainly observational.
MarseilleAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.