Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03838107Recruiting
Tracking changes in pediatric CRPS using study markers
This study looks at how signs in the body change over time in children with CRPS (complex regional pain syndrome). It mainly involves being assessed alongside the usual CRPS care, and often includes MRI checks to better understand the pain course.
Cincinnati, OhioAges 10–17 - NCT03850301Recruiting
Testing a brain inflammation target using an investigational medicine
This study tests whether a medicine that targets a specific brain inflammation marker (TSPO) can help in people with certain types of multiple sclerosis. It focuses on safety and whether the target can be measured and influenced during treatment.
London, EnglandAges 35–65 - NCT03851523Recruiting
Tracking memory changes in people with early Alzheimer’s symptoms
This study follows people over time to better understand how memory and thinking complaints progress in early Alzheimer’s disease (from “subjective cognitive decline” to mild cognitive problems). It may help researchers understand who is likely to decline and how symptoms change, which could support future treatments.
Barcelona, CataloniaAges 45 years+ - NCT03851484Recruiting
Study sensory symptoms in people with Tourette-related tics
This study looks at sensory symptoms in adults who have Tourette syndrome or similar long-term tic disorders. Your answers to questionnaires may help researchers understand these symptoms and how they relate to the condition.
Nashville, TennesseeAges 18 years+ - NCT03852381Recruiting
Spinal cord stimulation for nerve pain after back surgery
This study looks at how spinal cord stimulation (a device that sends mild signals to the spinal cord) affects nerve pain after lumbar surgery. It also aims to help predict who is most likely to improve and why, comparing patients with and without certain sensory symptoms.
Toronto, OntarioAges 18–80 - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT03856034Recruiting
Open vs minimally invasive surgery for spina bifida baby
This study compares two ways to correct spina bifida while the baby is still in the womb: an open operation (laparotomy) versus a minimally invasive endoscopic approach (percutaneous endoscopic). The goal is to see which approach leads to better outcomes for the baby and pregnancy.
Los Angeles, CaliforniaAges 18 years+ - NCT03858751RecruitingPhase 1/Phase 2
Drug to activate a sleep-control pathway for sleep apnea
This early study tests a medicine that is meant to improve how your brain and breathing muscles work during sleep for obstructive sleep apnea (OSA). If you qualify, you would be monitored during sleep to see whether the treatment changes breathing events and oxygen levels.
Boston, MassachusettsAges 18–70 - NCT03860233RecruitingPhase 1
Oxytocin added to CPAP for obstructive sleep apnea
This early study tests whether adding oxytocin to your usual CPAP treatment improves obstructive sleep apnea. It may help see if oxytocin changes how well CPAP works or how people feel while using it.
Washington D.C., District of ColumbiaAges 18 years+ - NCT03860857RecruitingPhase 3
Study biomarkers in memory aging and brain health
This Phase 3 study looks for blood/brain “biomarkers” linked to aging, memory changes, and early brain degeneration. It may help researchers better identify who is at risk and how biology relates to thinking and memory, using brain scans and thinking tests.
Irvine, CaliforniaAges 60 years+ - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT03865771Recruiting
Sleep study to improve memory in children with focal epilepsy
This study looks at how sleep affects memory in children with certain types of age-related focal epilepsy. It compares them to children hospitalized for non-nerve (non-neurologic) reasons to see whether sleep-related brain patterns relate to learning and memory.
NancyAges 6–13 - NCT03867539RecruitingPhase 4
Numbing shot and education to reduce opioids after carpal tunnel surgery
This study tests whether giving a long-lasting numbing injection (Exparel) plus education about pain management can help people avoid taking opioid pain pills after carpal tunnel release surgery. It may help reduce opioid use while still supporting comfort during recovery.
Dayton, OhioAges 18 years+ - NCT03868293Recruiting
Low-intensity ultrasound for drug-resistant temporal lobe seizures
This pilot study tests whether low-intensity focused ultrasound can reduce seizures in adults whose temporal lobe epilepsy hasn’t improved with at least two anti-seizure medicines. You may be asked to track seizure timing and undergo brain imaging before and during the study.
Boston, MassachusettsAges 18 years+ - NCT03867448Recruiting
Study of Hormone Conditions and How the Body Works
This study looks at people with known or suspected hormone (endocrine) conditions. It aims to improve understanding and clinical screening so doctors can better manage these conditions over time.
Bethesda, MarylandAges 18–90 - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03881930Recruiting
Balance therapy tailored with changed visual cues for neuropathy
This study tests a balance-retraining program that uses modified visual information to help people with neuropathy feel steadier while walking. You may benefit if your balance problems are linked to nerve-related sensitivity and you can safely participate in walking and standing exercises.
ParisAges 18 years+ - NCT03882827Recruiting
Natural history study of Duchenne muscular dystrophy in young boys
This study follows boys with Duchenne muscular dystrophy over time to better understand how the condition changes and how standard treatments affect health and function. It does not appear to test a new medicine, but it may help doctors plan better future care and studies.
BrusselsAges 4–9 - NCT03888924RecruitingPhase 2
BCG vaccine for people with radiologically isolated syndrome
This trial tests whether a BCG vaccine can help people who have radiologically isolated syndrome (RIS), a condition where MRI scans show signs of possible multiple sclerosis before symptoms develop. The study aims to see if vaccination is safe and can change disease behavior over time.
RomeAges 18 years+ - NCT03887481Recruiting
Brain stimulation study for a language-loss dementia subtype
This trial tests whether a painless form of brain stimulation can improve language and thinking skills in people with the logopenic variant of primary progressive aphasia (a dementia that affects language). You may receive brain stimulation along with repeated clinic visits to track changes over time.
Baltimore, MarylandAges 50–80 - NCT03887663Recruiting
Chinese Parkinson’s disease patient registry
This study is a registry that collects information from people with Parkinson’s disease to better understand the condition. You may help researchers learn about patterns of symptoms and care over time.
Changzhi, HunanAges Any age - NCT03890861Recruiting
Exercise program to help lower Alzheimer’s risk
This trial studies whether a structured group exercise program can help lower Alzheimer’s disease risk in older African Americans. You would be assigned to a group by chance and asked to attend regular sessions if it’s safe for you to exercise.
Baton Rouge, LouisianaAges 60 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.