Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07542158Enrolling by invitationPhase 2
Ultra-Low Radiation PET Imaging Study for Brain Scanning
This study tests a new way to take brain imaging scans (PET scans) using a very small amount of radioactive tracer. Researchers want to see if they can get clear pictures of your brain while reducing your radiation exposure compared to standard scans.
Englewood, New JerseyAges 18–120 - NCT07534319Recruiting
Brain Blood Flow Changes After Stroke Clot Removal
This study examines how blood flow in the brain changes after a minimally invasive procedure to remove a blood clot during an acute stroke. The research uses MRI imaging to understand brain recovery patterns and may help improve stroke treatment outcomes.
Zurich, Canton of ZurichAges 18 years+ - NCT07537426Recruiting
Acupuncture for Dry Eyes After Facial Paralysis
This trial tests whether tiny acupuncture needles placed under the skin can help relieve dry eyes and other eye discomfort that develops after long-lasting facial paralysis. The goal is to see if this treatment can improve symptoms when standard care hasn't worked well enough.
Hangzhou, ZhejiangAges 18–65 - NCT07542470Enrolling by invitationPhase 4
Cold and compression therapy after spinal surgery
This study compares a new cold and compression device (NICE1) to standard care after spinal surgery to see if it reduces pain and swelling. If you're having spine surgery, this trial tests whether keeping the area cold and compressed helps you recover better.
Sarasota, FloridaAges 18 years+ - NCT07541222Recruiting
Blood pressure medications and surgery recovery outcomes
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
KonyaAges 40 years+ - NCT07539441RecruitingPhase 1/Phase 2
Mirdametinib for brain and nervous system tumors
This trial tests a drug called mirdametinib for people with specific types of brain tumors or neurohistiocytosis (a rare condition affecting the nervous system). The drug targets mutations that cause these conditions to grow.
Basking Ridge, New JerseyAges 18 years+ - NCT07536542Recruiting
Dual-Task Training for Hand and Arm Function in Parkinson's
This study tests whether doing hand and arm exercises while performing a second task (like counting or listening) can improve movement and strength in people with Parkinson's disease. The goal is to help you move more smoothly and regain function in your hands and arms.
AnkaraAges 40–65 - NCT07539025Recruiting
How the Spinal Cord Learns and Adapts
This study explores how your spinal cord can learn and change through repeated movements. Researchers will ask you to participate in up to 4 sessions to understand how the nervous system adapts, which may help improve treatments for spinal cord injuries in the future.
New York, New YorkAges 18–80 - NCT07536503Recruiting
How Sleep Quality Affects Thinking and Function in MS
This study looks at whether better sleep helps people with multiple sclerosis (MS) think more clearly and stay more physically active. Researchers will measure your sleep quality and test your memory and everyday abilities to see if they're connected.
Ankara, AnkaraAges 18–65 - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT07540663Enrolling by invitation
Stem cells to improve spinal cord stimulation pain relief
This trial tests whether stem cells injected near your spinal cord can improve pain relief from your existing spinal cord stimulator (BurstDR device). You're only eligible if your current stimulator is already helping with at least 50% pain reduction.
Hasselt, LimburgAges 18 years+ - NCT07540117Recruiting
Social Prescribing to Improve Health in Older Adults
This study tests whether connecting older adults with community activities and exercise programs (like mindfulness and walking) can improve their overall health and quality of life. You'll participate in guided activities designed to keep you active and engaged in your community.
Zhunan, MiaoliAges 55 years+ - NCT07539792RecruitingPhase 2
New Skull Support Plates for Pituitary Tumor Surgery
This study tests a new type of absorbable (dissolvable) support plate used during minimally invasive surgery to remove tumors in the pituitary gland area. The plate helps support the surgical site as it heals. Researchers want to see if this new plate works safely and effectively compared to standard approaches.
Foshan, GuangdongAges 1–80 - NCT07536906Recruiting
Emergency Department Falls Study for Adults 65+
This study examines how doctors evaluate older adults who fall in the emergency department. Researchers want to better understand fall patterns and improve care for seniors after falls.
Boston, MassachusettsAges 65 years+ - NCT06749002Recruiting
Functional training for turning after stroke
This trial tests whether adding functional muscle training to turning-specific exercises helps people who have had a stroke turn more easily. It may benefit those who can walk with supervision and have no major memory or other neurological problems.
Islamabad, Punjab ProvinceAges 45–60 - NCT06748248Recruiting
Suspension therapy for mobility and balance in Down syndrome
This trial tests if suspension therapy (a type of physical therapy using supportive straps or harnesses) can help children with Down syndrome improve their ability to move and keep their balance. It may be a helpful option for children who can already stand and walk but want to get stronger and more stable.
Lahore, Punjab ProvinceAges 3–6 - NCT06749483Recruiting
Gut bacteria and infection in intensive care patients
This study looks at how gut bacteria affect severe infections in the ICU. It tests whether the microbiome can be a source of sepsis and a target for treatment. If you are critically ill or a long-term sepsis survivor, you might help find new ways to prevent infections.
Jena, ThuringiaAges 18 years+ - NCT07532642Recruiting
Head Position Changes With Special Vision Lenses
This study tests whether special prismatic lenses (lenses that bend light in a specific way) can help improve head and neck posture in people with Postural Deficiency Syndrome. Researchers will take X-rays and measurements before and after using these lenses to see if your head position improves.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07529054Recruiting
Robot-Assisted Walking Training After Stroke
This trial tests whether a robotic device that helps guide your walking can improve mobility and function after a stroke. If you've had a stroke at least 3 months ago and have some difficulty walking, this training might help you regain strength and independence.
Gröbming, StyriaAges 18–80 - NCT06751797Recruiting
Balance confidence and fear of falling in Parkinson's
This study looks at how confident people with Parkinson's are in their balance and whether fear of falling (kinesiophobia) affects their daily life. The goal is to better understand these factors so that future treatments can help people stay active and safe.
Istanbul, BeylikdüzüAges 50–80 - NCT07531745RecruitingPhase 1/Phase 2
ION337 gene therapy for children with Dravet syndrome
This study tests a new gene therapy called ION337 designed to treat Dravet syndrome, a severe childhood epilepsy caused by a SCN1A gene mutation. The therapy is given as a spinal fluid injection and aims to reduce seizures in children ages 2–12.
Ann Arbor, MichiganAges 2–12 - NCT07531719Recruiting
Risdiplam treatment study for type I and II spinal muscle atrophy
This study follows children with spinal muscular atrophy (SMA)—a genetic condition causing muscle weakness—who are being treated with a medicine called risdiplam. Researchers want to understand how well the treatment works and how it affects daily life in young patients.
CairoAges Up to 5 years - NCT07531511Recruiting
Understanding SLC6A1 Genetic Disorder in Children
This study tracks how children with SLC6A1 genetic mutations develop over time. Researchers will collect information about seizures, development, and daily functioning to better understand the condition and help guide future treatments.
New York, New YorkAges Up to 17 years - NCT07533942RecruitingPhase 2
Testing JZP3507 for Recurrent Grade 2 or 3 Brain Tumors
This study tests a new drug called JZP3507 for people with meningioma (a type of brain tumor, grades 2 or 3) that has come back or grown despite previous treatment. The goal is to see if this medication can slow or shrink the tumor.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.