Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03893916Recruiting
MEG vs EEG tests to find the epilepsy trigger before surgery
This study compares two brain tests—MEG and routine scalp EEG—to pinpoint where seizures start before surgery. It may help doctors choose the safest and most effective plan if you’re being considered for an epilepsy procedure.
BronAges 18–60 - NCT03894254Recruiting
Study of factors linked to memory and independence decline
This study looks for what predicts loss of day-to-day independence in people with memory problems. It aims to better understand early warning signs so care can be planned sooner.
Caluire-et-CuireAges 18 years+ - NCT03896529Recruiting
Study how aging and stress affect memory navigation
This study uses brain imaging (MRI) and controlled stimulation to understand how normal aging and stress affect memory and thinking, including how people navigate. It may help researchers learn what changes in the brain happen over time and with stress.
Atlanta, GeorgiaAges 65–80 - NCT03901924Recruiting
Ventilator settings to protect the breathing muscle
This study looks at a specific way to control a breathing machine (ventilator) to help prevent weakness of the diaphragm, the main breathing muscle, in newly intubated adults. You might be considered if you are newly on a ventilator for less than 36 hours and certain other conditions are not present.
Chicago, IllinoisAges 18 years+ - NCT03900221Recruiting
Pregnancy monitoring registry for multiple sclerosis in France
This study follows people who are pregnant and have multiple sclerosis (or related conditions) to better understand what happens during pregnancy. It does not appear to test a new treatment; it mainly collects health and pregnancy information.
AmiensAges Any age - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Birmingham, AlabamaAges 18 years+ - NCT03910010Recruiting
Brain scan study to study pain-related body signals in fibromyalgia
This study uses MRI brain scans to look for body “signals” (biomarkers) that may relate to chronic pain, including fibromyalgia. It may help researchers better understand what’s going on in the brain for people with long-term pain.
Halifax, Nova ScotiaAges 18–75 - NCT03912155Recruiting
Brain network study using implanted brain electrodes for epilepsy
This study looks at how brain connections work in people with drug-resistant partial epilepsy by analyzing signals from implanted electrodes done before surgery. It may help doctors better understand epilepsy and improve future pre-surgical evaluation.
MarseilleAges 12 years+ - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT03914378Recruiting
Study how radiation and cisplatin affect hearing in head and neck cancer
This study looks at how radiotherapy, and possibly cisplatin chemotherapy, affect hearing in people treated for head and neck cancer. It may help doctors better predict hearing side effects and plan hearing monitoring or prevention.
ManchesterAges 18 years+ - NCT03915418Recruiting
Screening sleep problems in children with cerebral palsy
This trial checks a new way to find sleep problems in children with cerebral palsy using connected tools (like devices/apps). It mainly helps by making sleep screening easier and more accurate, so families can get the right next steps sooner.
AngersAges 6–15 - NCT03920774Recruiting
Study of Familial Dysautonomia in People With IKBKAP Changes
This study looks at how familial dysautonomia (FD) progresses over time in people who have a confirmed IKBKAP genetic change. It may help doctors better understand the condition and plan future treatments.
New York, New YorkAges 4 years+ - NCT03922555RecruitingPhase 1
ASTX727 for IDH-mutant low-grade brain tumors
This early-stage study tests ASTX727 in adults with IDH-mutant gliomas that are coming back or progressing. It aims to see whether the medicine can slow the tumor and understand how it works in the body and tumor tissue.
Boston, MassachusettsAges 18 years+ - NCT03924791Recruiting
Epidural injection trial for acute sciatica pain
This study tests whether a specific back/nerve pain injection (an epidural injection) can help people with acute sciatica. You may qualify if your sciatica started a few weeks ago and your leg pain is still quite severe.
HaarlemAges 18 years+ - NCT03929549Recruiting
Testing a tool to predict jaw surgery failure for sleep apnea
This trial studies a way to predict which people with obstructive sleep apnea (OSA) may not do well after maxillomandibular advancement surgery (jaw advancement). It could help doctors choose the right treatment and avoid ineffective surgery.
Ann Arbor, MichiganAges 30–65 - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT03936361RecruitingPhase 3
Statins after a stroke bleed in the brain (Phase 3)
This trial studies whether continuing or stopping statin medicine after a spontaneous bleeding stroke in the brain (called lobar ICH) leads to better outcomes. It may help clarify if statins are safer to stay on—or better to pause—after this type of event.
Boston, MassachusettsAges 50 years+ - NCT03936647Recruiting
Testing a WEB device inside brain aneurysms
This trial studies whether placing a WEB device inside certain brain aneurysms can control the aneurysm and reduce risk. You might be considered if your aneurysm fits size and severity limits and your doctor thinks the WEB approach is appropriate.
Edmonton, AlbertaAges 18 years+ - NCT03940911Recruiting
Testing fatigue and muscle effects after starting targeted therapy
This study looks at how starting “targeted” treatment affects fatigue and skeletal muscle function in people with severe axial spondyloarthritis. It may help doctors understand what to expect early after treatment starts and how well it impacts day-to-day energy and muscle performance.
Strasbourg, Bas-RhinAges 18 years+ - NCT03944876RecruitingPhase 3
Botulinum toxin to block a facial nerve for chronic cluster headaches
This trial tests whether injections of botulinum toxin type A can reduce frequent, severe cluster headache attacks by targeting a facial nerve area. It’s for people whose cluster headaches have not responded well—or have caused side effects—to standard preventive treatments.
HamburgAges 18–85 - NCT03945448RecruitingPhase 2/Phase 3
Single-dose antifungal for people with HIV and positive cryptococcal blood test
This study tests whether a one-time antifungal treatment can help people with HIV who have a positive cryptococcal antigen blood test but no symptoms. It may lower the chance that this infection becomes a serious illness affecting the brain.
KampalaAges 15 years+ - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT03946930Recruiting
Study of memory decline in Alzheimer’s disease
This trial studies people diagnosed with Alzheimer’s disease who are at a moderate stage of decline. It likely involves cognitive (memory/thinking) testing and care-partner input to help track changes over time.
Hong KongAges 65–92 - NCT03948373Recruiting
Study of sleep apnea patients with normal blood pressure
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
LleidaAges 18–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.