Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT07526350RecruitingEarly Phase 1
MTS109 for Hard-to-Treat Autoimmune Diseases
This early-stage trial tests a new treatment called MTS109 for autoimmune diseases (like lupus, muscle inflammation, scleroderma, vasculitis, or Sjögren's syndrome) that haven't responded well to standard medications. The goal is to see if MTS109 can help control disease that keeps flaring or getting worse despite current treatments.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07527663Recruiting
GyroStim therapy for persistent symptoms after concussion
This study tests whether GyroStim—a specialized rotating chair therapy—can help reduce dizziness, balance problems, and thinking difficulties that last more than 4 weeks after a head injury. GyroStim is designed to retrain how your brain and inner ear work together.
Appleton, WisconsinAges 18 years+ - NCT07531732Recruiting
Self-Awareness and Social Thinking in Brain Diseases
This study explores how awareness of oneself and the ability to understand others' thoughts relates to two types of brain diseases: frontotemporal dementia (a disease affecting personality and behavior) and Alzheimer's disease. The research may help doctors better understand these conditions and improve care.
ParisAges 50–80 - NCT07530302Recruiting
Better ways to adjust CPAP therapy when it isn't working well
This trial tests whether a wearable device called Sunrise can help doctors adjust your CPAP machine better than standard sleep tests. If your current CPAP isn't stopping all your breathing pauses, this study may help find the right adjustments for you.
GrenobleAges 18–85 - NCT07527104Recruiting
Bone marrow cells and rehabilitation for cerebral palsy in young children
This trial tests whether transplanting cells from a child's own bone marrow, combined with rehabilitation therapy, can improve movement and function in young children with cerebral palsy caused by birth-related brain injury or bleeding. The goal is to see if this approach helps children move better and become more independent.
Hanoi, HanoiAges 6 months–18 years - NCT07528365Recruiting
Urea Treatment for Low Sodium Levels From SIAD
This trial tests whether urea can help treat dangerously low sodium levels in patients with SIAD (a condition where the body retains too much water) who haven't responded to drinking less fluid. Urea is a naturally occurring substance that may help restore normal sodium balance.
Turin, Piedmont, ItalyAges 18 years+ - NCT07530315Recruiting
Exercogs Study: Brain Training to Reduce Dementia Risk
This study tests whether Exercogs®—a computer-based brain training program—can help reduce your risk of memory problems and dementia. You'll do 60-minute sessions three times a week for 24 weeks if you have at least one treatable risk factor like high blood pressure, hearing loss, or physical inactivity.
SintraAges 55 years+ - NCT07532070Recruiting
Exercise and Therapy for Chronic Pain and Sleep Problems
This study tests whether exercise, talk therapy for sleep problems, or both together can help people with long-term back, hip, or knee pain who also struggle with sleep. You'll attend video appointments and try one of these approaches for several weeks.
San Antonio, NevadaAges 18 years+ - NCT07526987RecruitingPhase 3
Minocycline to Help Recovery After Acute Stroke Treatment
This study tests whether an antibiotic called minocycline, given alongside standard stroke treatment (clot-busting medication), can help reduce brain damage and improve recovery. You would receive minocycline around the time of your clot-busting treatment.
Liaocheng, ShandongAges 18–80 - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+ - NCT07526740Recruiting
Brain Stimulation and Training for Mild Memory Loss
This study tests whether combining brain stimulation (TMS) with cognitive training games can help people with mild cognitive impairment—early memory and thinking problems. The goal is to see if this combination improves thinking abilities and slows cognitive decline.
Charleston, South CarolinaAges 60–85 - NCT07528300Recruiting
Acupuncture for pain relief in muscle injury patients
This study tests whether a type of acupuncture called "battlefield acupuncture" can help reduce pain in people hospitalized with rhabdomyolysis—a serious muscle injury that causes muscle breakdown and pain. Researchers want to see if this treatment helps patients feel better while they're in the hospital.
TAMC, HawaiiAges 18–99 - NCT05610878RecruitingPhase 1
Stem cell help to improve fat grafting results
This early-phase study tests whether “preconditioned” stem cells from fat tissue can improve the look of fat transferred during liposuction and grafting. If you qualify, you may receive stem cells along with fat grafting to see how well it works and how safe it is.
Lahore, Punjab ProvinceAges 18–50 - NCT06684275Recruiting
Radiofrequency treatment comparison for trigeminal neuralgia pain
This trial compares two types of radiofrequency treatment (pulsed and thermal) to see which works better for people with trigeminal neuralgia, a condition that causes severe, stabbing facial pain. If you have had facial pain for at least six months that isn't controlled by medicine, this study may help you find relief.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06719791RecruitingEarly Phase 1
Sirolimus for hard-to-treat focal epilepsy
This trial tests if the drug sirolimus can help people with focal seizures (starting in one part of the brain) that don't improve with at least two other medications. It aims to reduce seizure frequency in adults aged 18 to 60.
BeijingAges 18–60 - NCT06744244Recruiting
Smell test for newborns with birth asphyxia
This study tests whether a simple smell test can help doctors better understand the risk of brain injury in newborns who had oxygen loss at birth. It may help identify babies who need extra monitoring without requiring cooling treatment.
ParmaAges 6 hours–3 days - NCT06753487Recruiting
Comparing two gentle therapies for piriformis syndrome in women
This trial tests two hands-on treatments (Facilitated Positional Release and Manual Myofascial Release) to see which works better for women with piriformis syndrome. If you're a woman aged 25–50 with buttock or hip pain for at least 2 months, this study might help you find relief.
Rawalpindi, Punjab ProvinceAges 25–50 - NCT06753006Recruiting
Research on stroke rehabilitation for arm weakness
This study tests a new rehabilitation program for people who have had a stroke within the last 6 months. It focuses on improving arm weakness using special therapy techniques.
Samara, Samara OblastAges 18–80 - NCT06752616RecruitingPhase 2/Phase 3
Study on calming severe agitation in psychiatric emergency rooms
This trial tests two different medications to quickly calm severe agitation in people admitted to a psychiatric emergency room. You may be able to join if you are extremely agitated and need urgent medication to help you settle down.
Copenhagen NAges 18–64 - NCT06755138Recruiting
Scoliosis, pain, and quality of life in Duchenne muscular dystrophy
This study looks at how scoliosis (curved spine) and back pain affect daily life in people with Duchenne muscular dystrophy. Researchers will measure muscle strength and compensation patterns to understand these links.
SeoulAges 11–30 - NCT07520565RecruitingPhase 3
Emergency stroke treatment with BXOS110 within 3 hours
This trial tests whether BXOS110, an experimental injection, can help people recover better after an acute ischemic stroke (a stroke caused by a blood clot) when given within 3 hours of symptom onset. The study compares BXOS110 to a placebo to see if it reduces disability and improves recovery.
Hengshui, HebeiAges 18–85 - NCT06752252Recruiting
Nerve blocks for pain after hernia repair in children
This study compares two types of nerve blocks (paravertebral and erector spinae) to see which one provides better pain relief after hernia surgery in children. The goal is to help children feel more comfortable after their operation.
El SharkiaAges 2–12 - NCT05672225Recruiting
Dexmedetomidine IV pain pump during major abdominal surgery
This trial studies a two-part pain pump given through a vein during major laparoscopic abdominal surgery to help control pain with general anesthesia. It may help by improving comfort while also avoiding certain side effects for people who can safely receive the study medicine.
SeoulAges 20 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.