Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04559373Recruiting
Virtual reality training to improve community walking after stroke
This trial tests whether virtual reality plus field (real-world) practice can improve walking and related thinking/vision skills after stroke. It may help you walk more safely and confidently in everyday community settings (like getting around outdoors).
Laval, QuebecAges 40–74 - NCT04559919Recruiting
Building a regional database for people with epilepsy
This study collects information about adults who have had an unprovoked seizure or who have epilepsy. The goal is to better understand epilepsy in the community and improve future care.
BoråsAges 18 years+ - NCT04560140Recruiting
Support after stroke to help young adults return to daily life
This study tests a community program to help young adults after a stroke rebuild independence at home and back to normal routines. It’s aimed at people who still need support with daily activities but are able to join all sessions and communicate in Cantonese.
Hong KongAges 18–64 - NCT04561518Recruiting
Study of people with TTR amyloidosis worldwide
This is an observational study (no study drug) for people with transthyretin (TTR)–mediated amyloidosis, including people who carry certain gene changes before symptoms begin. It may help researchers better understand how the disease affects health over time and what to measure in future treatments.
La Jolla, CaliforniaAges Any age - NCT04561557RecruitingEarly Phase 1
Cell therapy for relapsing nervous system autoimmune diseases
This early-phase trial tests CT103A “CAR-T” cell therapy to treat certain relapsing or treatment-resistant autoimmune diseases that affect the nervous system. It aims to see whether the cells are safe and may help reduce disease activity when standard treatments haven’t controlled symptoms.
Wuhan, HubeiAges 18–75 - NCT04562194Recruiting
Registry study for people already treated with NeVa thrombectomy
This registry study follows people who have already had a specific clot-removal procedure using the NeVa device. It helps doctors understand how the device performs in real-world care for certain kinds of stroke.
MendozaAges 18 years+ - NCT04565925RecruitingPhase 2
Sildenafil to reduce urine leaks after spinal cord injury
This trial studies whether sildenafil (a prescription pill) can lessen urinary incontinence in adults with spinal cord injuries. If it works, it may reduce the number of urine leakage episodes each week.
College Station, TexasAges 18–70 - NCT04566991RecruitingPhase 2
Deferoxamine after aneurysm brain bleed to improve recovery
This trial studies deferoxamine, a medicine that targets iron-related injury, in people with an aneurysmal subarachnoid hemorrhage (a brain bleed caused by a burst aneurysm). It aims to improve neurologic recovery after the aneurysm is treated.
Ann Arbor, MichiganAges 18–80 - NCT04569591Recruiting
Using DDAVP with PET scans to find pituitary tumor source
This study tests whether giving DDAVP before a PET scan can help doctors better locate the pituitary problem in people with Cushing disease. It may help confirm where the ACTH-producing tumor is so surgery can be planned more accurately.
Bethesda, MarylandAges 8–99 - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+ - NCT04572503Recruiting
Surgery for mild to moderate sleep apnea not helped by CPAP
This trial looks at a modified palate surgery to treat mild to moderate obstructive sleep apnea in people whose CPAP machine isn’t working for them. It may help if your sleep apnea is caused by the tissue behind the soft palate collapsing rather than other airway areas.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT04573660Recruiting
Registry for people using Abbott vascular devices
This is a patient registry that collects health information from adults who get Abbott vascular devices during a planned procedure. It helps Abbott and doctors understand how these devices perform in everyday care.
Birmingham, AlabamaAges 18 years+ - NCT04573140RecruitingPhase 1
RNA vaccine study for newly diagnosed adult and pediatric brain tumors
This Phase 1 trial studies an “RNA-lipid particle” vaccine given after surgery for certain newly diagnosed brain cancers (glioblastoma in adults, high-grade glioma in children/teens). The goal is to see whether the vaccine is safe and can train the immune system to fight the tumor.
Washington D.C., District of ColumbiaAges 4 years+ - NCT04576078RecruitingPhase 2
Nefopam for less pain after knee replacement surgery
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
Lyon, LyonAges 18–75 - NCT04574037Recruiting
Predicting arm recovery after stroke
This study tries to predict how well your arm movement may improve after a stroke. It uses brain and/or nerve testing (like MRI and TMS) and could help doctors plan the best rehabilitation for you.
ParisAges 18 years+ - NCT04574440Recruiting
Near-infrared brain scan during planned heart surgery
This trial tests a non-painful near-infrared brain scan (placed on the forehead) during planned adult heart surgery. It may help doctors better understand how the brain responds during surgery and improve care.
London, OntarioAges 18 years+ - NCT04573673Recruiting
Tapping the shin nerve to help bladder control in MS
This study tests a noninvasive nerve stimulation applied to the lower leg to improve bladder emptying problems in people with multiple sclerosis. It may help reduce bladder dysfunction while you keep using clean intermittent self-catheterization.
LilleAges 18–65 - NCT04575337Recruiting
Biomarker study to help detect Alzheimer’s early
This study looks for brain/biological “signals” (biomarkers) that may identify Alzheimer’s disease earlier, including stages before clear symptoms. You may be followed for about 5 years, with repeated memory and thinking testing to see how these signs relate to future diagnosis.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04579120Recruiting
Brain scan study in healthy aging or early Alzheimer’s
This study uses brain imaging to understand changes in the brain during normal aging and early Alzheimer’s disease (AD). It may help researchers spot early brain changes and evaluate how well imaging measures those changes.
St Louis, MissouriAges 18 years+ - NCT04578249Recruiting
Blocking blue light at night after heart surgery
This trial tests whether reducing blue light at night after certain planned heart surgeries helps protect mood, thinking, and recovery. If you have no history of major mental health problems or organ problems, you may be able to join the study.
Morgantown, West VirginiaAges 45–75 - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT04587648Recruiting
Treating cardiac amyloidosis in heart failure with preserved ejection
This trial studies people with heart failure with preserved ejection fraction (HFpEF) and cardiac amyloidosis (an abnormal protein buildup in the heart). It may help researchers understand better treatment for symptoms and heart function in this group.
TaipeiAges 60 years+ - NCT04588285RecruitingPhase 2
Ambroxol for new and early dementia with Lewy bodies
This trial tests whether ambroxol (a mouth medicine) can help people with new or early dementia with Lewy bodies (DLB) or mild cognitive impairment linked to DLB. Participants take the medicine for about 18 months while the study tracks safety and changes over time.
Haugesund, HaugesundAges 50–85 - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.