Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04776824Recruiting
Swiss registry for people with amyloidosis and possible heart involvement
This trial is a registry that collects health information from people with amyloidosis, including cases where the heart may be involved. Sharing your medical details can help researchers learn how this condition affects patients and may guide future care.
BaselAges 18 years+ - NCT04777825Recruiting
Biofeedback training to help heart-rate stress signals
This trial studies whether heart-rate variability biofeedback training can reduce distress and symptoms in people whose symptoms seem physical but are linked to psychological factors (somatoform-related issues). It may help you learn to better control stress-related body signals through training sessions.
MontpellierAges 18–75 - NCT04781452Recruiting
Testing treatment for people with significant disabilities
This trial studies a treatment in people with intellectual disability and/or severe multiple disabilities. It may help participants and caregivers learn whether the treatment is safe and potentially beneficial for this group.
Aachen, North Rhine-WestphaliaAges 18–80 - NCT04782284Recruiting
Swallowing therapy for people with MSA and swallowing trouble
This study tests a comprehensive swallowing rehabilitation program for people with MSA (a nervous system condition) who have trouble swallowing. If you qualify, you may get structured swallowing therapy aimed at improving how safely you swallow.
SeoulAges 19 years+ - NCT04782830Recruiting
Wearable sensor study for low blood pressure on standing
This study uses an accelerometer (a wearable motion sensor) to measure symptoms and blood pressure changes when you stand up. It may help doctors better track how neurogenic orthostatic hypotension affects you and how well current treatments are working.
Nashville, TennesseeAges 40–80 - NCT04782947RecruitingPhase 2/Phase 3
Training with back stimulation after traumatic spinal cord injury
This trial studies whether epidural (back-of-spine) stimulation plus guided resistance training can improve strength and function after a traumatic spinal cord injury. It may help people who have an intact nerve pathway below their injury level and can safely use a rehab exoskeleton.
Richmond, VirginiaAges 18–60 - NCT04785976Recruiting
Study of long-term outcomes after a ruptured brain aneurysm bleed
This trial is a long-term follow-up study of people who come to the emergency room with a ruptured brain aneurysm (bleeding in the space around the brain). It helps doctors understand what outcomes are most common and what may affect recovery over time.
Beijing, Beijing MunicipalityAges Any age - NCT04789616RecruitingPhase 2
Maraviroc plus stroke rehab to improve recovery
This study tests whether maraviroc (or a placebo) given soon after an ischemic stroke can improve how well people recover with inpatient rehabilitation. It may help some stroke survivors regain arm and/or leg function faster with the usual rehab therapies.
Calgary, AlbertaAges 18 years+ - NCT04789044RecruitingPhase 2
PEG treatment to improve nerve repair after upper-arm injury
This Phase 2 study tests a PEG-based approach meant to help damaged peripheral nerves heal and regain movement and feeling after an upper-arm/hand nerve injury. You may be screened quickly after injury to see if the nerve pattern and your health situation fit the study plan.
Baltimore, MarylandAges 18–80 - NCT04791540Recruiting
Rehab study for people with a tracheostomy and low muscle strength
This study looks at how nutrition and muscle health affect recovery during rehabilitation for people who have a tracheostomy (a breathing opening in the neck). It may help the rehab team improve food and care plans to support strength and overall health.
Florence, ItalyAges 18 years+ - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT04792554Recruiting
Study of aging around major non-heart surgery
This study looks at changes in health and function in older adults before and after major surgery. It may help doctors understand how “aging” affects recovery and what could improve outcomes.
SingaporeAges 65–100 - NCT04792606Recruiting
Study tracking long-term hip outcomes in non-walking children
This study follows children with cerebral palsy who cannot walk (severe type) and have hip displacement, to see how hip treatment affects long-term outcomes. You may be asked your child’s caregivers to complete a questionnaire so researchers can compare results over time.
Toronto, OntarioAges 2–19 - NCT04792931Recruiting
Study for adults with suspected autoimmune muscle disease
This study looks at adults who may have an autoimmune (self-immune) muscle disease. It aims to better understand and evaluate this condition, which may help guide future diagnosis and care.
BrestAges 18 years+ - NCT04794686Recruiting
Study for children with a brain tumor with multilayer rosettes
This registry research program collects information and tumor samples from people with a specific type of brain embryonal tumor (with multilayer rosettes). It may help researchers understand the tumor better and improve future treatments.
Hackensack, New JerseyAges Any age - NCT04796506Recruiting
Tracking sleep changes to improve thinking in Parkinson’s
This study looks at whether changes in “slow wave sleep” (a deep sleep stage) match improvements in thinking for people with Parkinson’s. It uses an exercise/recovery-focused approach and checks sleep and thinking scores to see if these changes go together.
Aurora, ColoradoAges 45–100 - NCT04796714RecruitingPhase 4
Aspirin and clopidogrel after left heart appendix closure
This trial studies a “double anti-platelet” medicine plan (aspirin plus clopidogrel) after closing the left atrial appendage, a procedure used to reduce stroke risk in some heart rhythm conditions. It aims to find a safer, better medicine strategy for people who cannot take standard blood thinners.
PessacAges 18 years+ - NCT04798131Recruiting
Brain-scan training to reduce medication-resistant voices
This study uses brain scans (MRI) and real-time feedback to help train the brain to reduce frequent, distressing auditory hallucinations (hearing voices) in people with schizophrenia. If you qualify, you may try a structured neurofeedback program while researchers track changes in your symptoms.
LilleAges 18–60 - NCT04798651Recruiting
Study immune blood and spinal fluid cells in multiple sclerosis
This study looks at different immune cells in blood and, sometimes, spinal fluid (CSF) to understand what’s driving multiple sclerosis (MS) or early MS-like symptoms. Your participation may help researchers better explain the disease and potentially improve how it’s diagnosed or treated.
BordeauxAges 18 years+ - NCT04800484Recruiting
Test how different AFO heel height and stiffness affect walking
This study looks at how changing the heel height and stiffness of an AFO (a brace you wear on your lower leg/foot) changes your walking pattern. The goal is to learn which brace settings may improve comfort and walking.
Iowa City, IowaAges 18–70 - NCT04800588Recruiting
Computer tests to study early Alzheimer’s changes
This study uses computer and touch-screen tasks to measure thinking changes in people who may be in the early, symptom-free stage of Alzheimer’s disease. It aims to understand how these brain-related changes show up on testing, which could help future detection or tracking.
Berkeley, CaliforniaAges 18–89 - NCT04800913Recruiting
Imaging tests during left atrial appendage closure
This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.
BudapestAges 18 years+ - NCT04801589RecruitingPhase 3
Guided sedation for children on a breathing machine
This study tests a “goal-directed” approach to sedation (giving the right amount based on target goals) for children who need a breathing machine in the pediatric ICU. The goal is to reduce brain and recovery side effects while keeping children comfortable and safe.
Nashville, TennesseeAges 10 months–11 years - NCT04802135Recruiting
Register for babies with early-onset epileptic brain disorders
This trial builds a long-term list (register) of babies whose seizures start within the first month of life and who need anti-seizure medicine. The goal is to better understand these conditions and support future research that could lead to better care.
AngersAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.