Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT04535349Recruiting
Imaging heart uptake of bone tracer in ATTR amyloidosis
This study uses special imaging tracers to see how much they build up in the heart in people with cardiac transthyretin (ATTR) amyloidosis. It may help researchers better measure disease activity and understand who benefits from treatments like tafamidis.
CaenAges 18–100 - NCT06247631Recruiting
Sleep apnea risk before chest surgery
This study uses a simple questionnaire (STOP-Bang) to check if patients having chest surgery might have undiagnosed sleep apnea or face breathing challenges during surgery. It helps doctors plan safer care.
Ankara, KeçiörenAges 18–65 - NCT06550596Recruiting
Amnion membrane for diabetic foot ulcers
This trial tests a wound covering made from donated amniotic tissue (dehydrated human amnion membrane) placed on a diabetic foot ulcer that isn't healing. It aims to see if adding this membrane to standard wound care helps the ulcer close faster.
Thousand Oaks, CaliforniaAges 18 years+ - NCT06742697Recruiting
Exercise program to improve walking in Hereditary Spastic Paraplegia
This study tests a combined exercise program with flexibility, strength, aerobic, and movement training to see if it helps improve walking in adults with Hereditary Spastic Paraplegia. Participants attend at least 10 supervised sessions over several weeks.
Bosisio Parini, LombardyAges 18 years+ - NCT06788808Recruiting
Ultrasound study of fetal brain development in pregnancy
This study uses ultrasound to examine fetal brain and spine development in pregnant women. It compares scans from pregnancies where a brain or spine issue is suspected with those from healthy pregnancies to improve understanding and diagnosis.
Bologna, BolognaAges 18–45 - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT07445854Recruiting
Sensory mapping after nerve blocks for gallbladder surgery
This trial measures how different regional anesthesia techniques affect sensation on the skin. It may help doctors understand how to better manage pain after gallbladder surgery.
Samsun, IlkadımAges 18–75 - NCT07447804Recruiting
Diaphragm and Breathing Strength in Hemiplegia Patients
This study looks at how hemiplegia affects the diaphragm (the main breathing muscle) and your breathing strength. It aims to help guide rehabilitation after a stroke.
Istanbul, AtaşehirAges 18–80 - NCT07452276Recruiting
AI brain training for stroke recovery
This trial tests a computerized brain-training program that uses artificial intelligence to help people with memory problems after a stroke. If you are between 45 and 60 and had a stroke at least 3 months ago, you may be able to join.
Cairo, EgyptAges 45–60 - NCT07448233Enrolling by invitation
AI health management for epilepsy in rural areas
This trial tests a smartphone-based AI system to help manage epilepsy long-term in rural areas. It is for people who have had at least one convulsive seizure in the past year and can use a smartphone with a caregiver.
Xi'an, ShaanxiAges 18–65 - NCT07447284Recruiting
Improving sleep for African American couples with OSA
This study tests whether a couple-based approach helps African American patients with moderate to severe sleep apnea stick with CPAP therapy better. It is designed for patients and their bed partners who want to improve sleep health together.
Cleveland, OhioAges 30 years+ - NCT07448350Recruiting
TENS therapy for better sensation after leg amputation
This study tests if a gentle electrical stimulation method called TENS can help people who have lost a leg below or above the knee feel more natural sensations in their missing limb and reduce phantom limb pain.
Rome, RomeAges 18–80 - NCT07448883Recruiting
How well a Turkish scale measures spinal cord compression
This study tests a Turkish translation of a spinal cord function scale (mJOA) in people with degenerative cervical myelopathy. It helps doctors and patients better understand and track symptoms.
Buca, İzmirAges 18 years+ - NCT07449000Recruiting
Losartan for corneal scar treatment
This trial tests if losartan, a common blood pressure medicine, can help reduce corneal scars. It may be an option for adults with a stable corneal scar that has been present for at least one month.
Monterrey, Nueo LeonAges 18 years+ - NCT07451613RecruitingPhase 1/Phase 2
Stem cell therapy trial for Huntington's disease
This trial tests whether human neural stem cells are safe and tolerable for people with Huntington's disease. It involves a neurosurgical procedure to inject the cells into the brain, along with MRI scans and other monitoring.
Irvine, CaliforniaAges 18–65 - NCT07452562Recruiting
Hesperidin supplement for multiple sclerosis
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can help people with MS. It aims to see if it is safe and well-tolerated.
Swansea, WalesAges 18 years+ - NCT07452939Recruiting
Brain stimulation to help memory after ICU delirium
This study tests if a noninvasive brain stimulation technique called theta burst stimulation can improve thinking and memory problems that can happen after a stay in the ICU with delirium. It may help people who are still having cognitive issues a few months after leaving the hospital.
Gainesville, FloridaAges 50–75 - NCT07446634Recruiting
Jaw advancement surgery for sleep apnea
This study tests jaw advancement surgery for people with obstructive sleep apnea who haven't been helped by CPAP or mouthpieces. It looks at whether moving the jaw forward can improve breathing during sleep.
Falun, Dalarna CountyAges 18–70 - NCT07449117Recruiting
Brain stimulation for language in mild cognitive decline
This study tests a new type of gentle brain stimulation (called temporal interference) to see if it can improve language processing in people with mild cognitive impairment. The stimulation uses electrodes placed on the head and is done while you are in an MRI scanner.
Brno, South MoravianAges 60–80 - NCT07447999Recruiting
Using AI to predict sleep apnea severity
This trial tests whether a special computer model can predict sleep apnea severity using a stethoscope and a fingertip oxygen sensor, instead of a full sleep test. It might help people get faster and easier sleep apnea diagnosis.
New Taipei CityAges 30–75 - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT07448103Recruiting
Robot-assisted rehab for kids with brain injury
This trial uses a social robot and artificial intelligence to help children with acquired brain injury do rehabilitation exercises at the hospital or at home. The robot guides them through arm and hand activities to improve movement and recovery.
Madrid, MadridAges 7–16 - NCT07447934Recruiting
Vibration therapy for leg muscle stiffness
This trial tests if gentle vibrations can reduce muscle stiffness (spasticity) in the lower leg after a neurologic condition like stroke or brain injury. You may join if you've had spasticity for at least 6 months and can stand with or without help.
New York, New YorkAges 18–85 - NCT07450690Recruiting
Exercise training for muscle function in mitochondrial myopathy
This study tests whether exercise training can improve muscle function in adults with mitochondrial myopathy, a condition that affects how muscles produce energy. Participants will follow an exercise program to see if it helps their muscle strength and daily activities.
CopenhagenAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.