Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05179473Recruiting
Predict and diagnose stiffness after a recent stroke
This study looks at how to predict and measure spasticity (muscle stiffness and tightness) in people after a recent stroke. It may help clinicians better diagnose and understand what to expect as you recover.
Montreal, QuebecAges 18–85 - NCT05180786Recruiting
Brain-training therapy to improve arm movement after stroke
This study tests a learning-and-recovery approach meant to help people regain arm and hand control after a long-term stroke. It targets patients with specific movement and brain-connection patterns so the training can be safely done.
Chicago, IllinoisAges 18 years+ - NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT05183672Recruiting
Phone-based check-ins after stroke using a nurse clinic
This trial tests whether nurse-led telecare (phone/video check-ins) can improve follow-up care after a recent stroke. It may help you get timely support from home rather than frequent in-person visits.
KowloonAges 18 years+ - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05187000Recruiting
Personalized brain stimulation for patients in coma after brain injury
This study tests whether personalized repetitive brain stimulation (rTMS) can improve symptoms in people diagnosed with disorders of consciousness after a recent brain injury. It compares treatment in a steady, safe way and checks whether the stimulation target matches your brain scan.
Guangzhou, GuangdongAges 18–70 - NCT05187650Recruiting
Powered exoskeleton plus electrical stimulation for incomplete spinal cord injury
This trial tests whether a powered walking exoskeleton together with electrical muscle stimulation (FES) can improve walking and movement in people with long-term, incomplete spinal cord injury. It may help you stand and walk more safely and effectively than standard care alone.
Nottwil, Canton of LucerneAges 18 years+ - NCT05187819Recruiting
Blood test to help diagnose possible Alzheimer’s
This trial checks whether a simple blood test can help doctors diagnose Alzheimer’s in people who seem to have memory problems. If you’re being evaluated for possible dementia, your doctor may refer you to a memory clinic for testing and follow-up.
StavangerAges 40–100 - NCT05188183Recruiting
Remote brain stimulation plus hand training for phantom limb pain
This trial tests whether remote brain stimulation (tDCS) combined with sensory (hand/limb) training can reduce phantom limb pain. It also uses computer prediction (“machine learning”) to estimate who is most likely to benefit.
Cambridge, MassachusettsAges 18 years+ - NCT05189600Recruiting
Testing breathing wave signals to improve airway treatment
This trial studies whether special breathing recordings taken during assisted air “insufflation–exsufflation” can show how your larynx (voice box) responds. The goal is to use those signals to fine-tune the best treatment settings for people with neuromuscular conditions.
LondonAges 18 years+ - NCT05191264Recruiting
Screws plus cement to treat bone metastases
This trial looks at a treatment that uses metal screws along with cement to stabilize and treat weakening spots in bones caused by metastases. It’s meant for people who have already received this type of procedure and want to be included in the study.
Saint-EtienneAges 18 years+ - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT05193396RecruitingPhase 4
Hydrocortisone trial for adrenal symptoms after stopping steroid pills
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
AarhusAges 50 years+ - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05194397RecruitingPhase 2
Exercise plus NR supplement to boost fitness after stem-cell transplant
This trial tests whether a supervised exercise program, plus an NR supplement, can improve fitness in young people who have had an allogeneic (donor) stem-cell transplant for certain blood cancers or bone marrow conditions. It’s meant to help with energy and physical ability while monitoring safety.
Duarte, CaliforniaAges 10–30 - NCT05194566Recruiting
Brain stimulation for long-term speech trouble after stroke
This study tests whether a form of brain stimulation can improve naming words in people who still have language problems (aphasia) more than 6 months after a stroke. It may help people find and say words more accurately during a naming task.
Chicago, IllinoisAges 18–80 - NCT05194787Recruiting
Online tests to spot early Alzheimer’s changes
This study looks at whether online motor (movement) and thinking tasks can detect early changes related to Alzheimer’s disease. You may be able to take part if you’re over 50 and do not already have a diagnosis of dementia.
Hobart, TasmaniaAges 50 years+ - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+ - NCT05196984Recruiting
Gamma brain stimulation study for adults with Down syndrome
This trial tests a brain stimulation approach aimed at affecting brain activity in people with Down syndrome. It may help researchers understand whether this kind of stimulation can improve certain brain or thinking-related outcomes.
Cambridge, MassachusettsAges 25–65 - NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT05197738Recruiting
Study using a sleep health app to improve sleep
This study tests a “sleep health” app (REFRESH) to see how it may help people track and improve sleep. You may be eligible if you’re an adult in the U.S. who can use the app on your own phone.
La Jolla, CaliforniaAges 18 years+ - NCT05197764Recruiting
Track muscle growth in young children with spastic cerebral palsy
This study looks at how the muscles in the body grow in infants and young children with spastic cerebral palsy (a type of movement difference). It may help doctors better understand normal growth patterns and how care choices affect muscle development.
Leuven, Vlaams-BrabantAges 6 months–9 years - NCT05198076Recruiting
TMS follow-up study for balance changes in Parkinson’s
This study looks at how “high-frequency TMS” (a brain stimulation treatment) may change balance in people with Parkinson’s disease over a 6-month follow-up. You may be considered if you have mild to moderate Parkinson’s, have not had TMS before, and are medically stable.
Giza, Ad Doqi, Giza District, Giza GovernorateAges 55–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.