Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07390552RecruitingPhase 2
Study of PLH-2301 for muscle loss in older adults
This trial tests an experimental medicine called PLH-2301 to see if it can help improve muscle strength and function in people with age-related muscle loss (sarcopenia). It may be an option if you are 65 or older, have been diagnosed with sarcopenia, and can walk on your own.
Seongnam-si, Gyeonggi-doAges 65 years+ - NCT06830356Recruiting
PET-guided radiation for high-risk meningiomas
This trial uses a special PET scan to find active tumor areas and then delivers a stronger dose of radiation to those spots. It is for people with aggressive or returning meningiomas who have not had brain radiation before.
Aviano, PordenoneAges 16 years+ - NCT06828926Recruiting
Tai Chi study for older adults with memory concerns
This study tests whether tai chi can improve thinking, memory, and overall well-being in older adults who have mild memory problems (Mild Cognitive Impairment) or are healthy. It looks at how tai chi affects the brain and daily life.
Athens, OhioAges 60 years+ - NCT06829290Recruiting
How muscle loss affects disease course in GI cancers
This study looks at how loss of muscle mass (sarcopenia) affects the course of illness in people with gastrointestinal cancers, liver cirrhosis, or those in the ICU. It will help doctors better understand and treat muscle wasting.
Mainz, Rhineland-PalatinateAges 18 years+ - NCT06830421RecruitingPhase 3
High-dose chemo with stem cell transplant vs. standard therapy for older adults with CNS lymphoma
This study compares a high-dose chemotherapy followed by your own stem cell transplant to standard chemo-immunotherapy for older adults with newly diagnosed primary CNS lymphoma. The goal is to see which approach works better and is safer for people over 70.
Freiburg im Breisgau, Baden-WurttembergAges 65 years+ - NCT07389213Recruiting
Can brain stimulation and hearing aids slow memory loss in older adults with hearing loss?
This trial tests whether a non-invasive brain stimulation technique (rTMS) combined with hearing aids can help slow down thinking and memory decline in older adults who have age-related hearing loss.
Guangzhou, GuangdongAges 50–85 - NCT07390539RecruitingPhase 1
CAR T cells targeting B7-H3 for brain tumors
This trial tests a new type of immune therapy (CAR T cells) that targets a protein called B7-H3 found on some brain tumors. It is for children and young adults with certain brain or spinal cord tumors that have come back after standard treatment, and aims to see if the treatment is safe and effective.
Boston, MassachusettsAges 2–21 - NCT07389135Recruiting
Heart rate and anxiety after nose surgery study
This study looks at whether your heart rate patterns and anxiety levels before surgery can predict how you will wake up after nose surgery (septorhinoplasty). If you are scheduled for this surgery, they will measure your heart rate and ask you questions about anxiety to see if these can help reduce confusion or agitation when you wake up.
Konya, KaratayAges 18–65 - NCT07394608Recruiting
Vagus nerve stimulation for teens with cerebral palsy
This trial tests if a gentle, non-invasive nerve stimulation (using a device placed on the neck) can improve hand and movement function in adolescents with spastic cerebral palsy. It aims to find new ways to help with rehabilitation.
New York, New YorkAges 12–17 - NCT07392879Recruiting
Virtual nature walks for depression in MS
This study tests whether virtual reality nature walks can help improve depression in people with progressive multiple sclerosis. You will use a VR headset at home to watch calming nature scenes, and researchers will see how it affects your mood.
Ann Arbor, MichiganAges 18 years+ - NCT07392723RecruitingPhase 2
Flaxseed nutrition to protect memory in APOE4 adults
This study tests a special flaxseed-based nutrition drink to see if it can slow memory loss in older adults who have the APOE4 gene and mild cognitive impairment (early memory trouble). If you qualify, you'll take the drink daily for a year and have memory tests and brain scans.
New Brunswick, New JerseyAges 60 years+ - NCT07396025Enrolling by invitation
Study of surgery for blocked carotid arteries
This trial looks at how well surgery and diagnostic tests work for people with a blocked carotid artery (the main artery in the neck that supplies blood to the brain). It may help if you have reduced blood flow to part of your brain and are able to understand instructions and communicate.
AstanaAges 18 years+ - NCT07396246RecruitingPhase 2
Comparing two treatments for hip pain
This trial tests if a new artery-blocking procedure works better than platelet-rich plasma shots for people with chronic hip pain (greater trochanteric pain syndrome) who haven't improved with physical therapy or anti-inflammatory drugs.
GuimarãesAges 18–80 - NCT07397377Recruiting
Brain stimulation for slow movement in Parkinson's
This study tests whether a gentle form of brain stimulation (called prTMS) can help improve slow movement in people with Parkinson's. You would come to the Danish Research Centre for Magnetic Resonance for several sessions. The goal is to see if this non-invasive treatment can make daily tasks a bit easier.
HvidovreAges 18–80 - NCT07397559Recruiting
Spinal cord stimulation for spinal cord injury recovery
This trial tests a spinal cord stimulation device to help people with chronic spinal cord injury regain leg movement. It aims to improve muscle control and function.
St Louis, MissouriAges 16–65 - NCT07396454RecruitingPhase 2
Radiation plus anlotinib for HER2-negative breast cancer brain metastases
This trial tests whether adding anlotinib (a targeted therapy) to standard radiation can better control breast cancer that has spread to the brain. It is for people with HER2-negative breast cancer and at least one brain tumor seen on MRI.
NanjingAges 18–70 - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT07393620Recruiting
Predicting brain outcomes in newborns with mild oxygen loss
This study uses brain monitoring and oxygen measurements in newborns who had a mild lack of oxygen at birth to see if these tests can predict how the baby will develop. The goal is to find early signs that might help guide care.
BursaAges birth–6 hours - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT07389590RecruitingPhase 4
Switching MS drugs for wearing-off symptoms
This study tests whether switching from ocrelizumab to a similar drug, ublituximab, can help people with MS who experience 'wearing-off' symptoms before their next infusion. It may offer a new option to keep symptoms more stable between doses.
Baltimore, MarylandAges 18–65 - NCT07392554Recruiting
Virtual reality for public speaking practice
This trial tests if virtual reality can help higher education students improve their public speaking skills. You'll use a VR program to practice speaking in front of an audience, which may reduce anxiety and improve your confidence.
Liège, LiègeAges 20–30 - NCT07393880Recruiting
Sound and training for chronic tinnitus
This trial combines sound therapy with electrical stimulation and auditory training to reduce chronic tonal tinnitus. It may help if you have had constant ringing in your ears for more than 3 months but less than 5 years.
Dublin, DublinAges 18–80 - NCT07390136Recruiting
Brain development study for babies with and without early brain injury
This study looks at how babies' brains develop, comparing infants who had a brain injury around birth with healthy babies. It could help understand early thinking and learning abilities.
Madison, WisconsinAges 3 months–2 years
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.