Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05539560Recruiting
Olfactory training for loss of smell after COVID-19
This trial studies whether daily smell training can improve smell loss caused by COVID-19. It may help people regain smell and possibly reduce related symptoms like distorted smells.
CopenhagenAges 18 years+ - NCT05539677Recruiting
Research biobank and patient registry for aggressive solid tumors
This study builds a biobank and patient registry using tumor samples and blood. It helps researchers better understand aggressive cancers and may improve future treatments by testing immune (defense) responses.
Saint PetersburgAges 1 year+ - NCT05539859Recruiting
Brain bleed surgery trial using endoscope for deep brain bleeding
This trial tests whether a minimally invasive brain surgery using an endoscope can improve outcomes for people with a deep brain bleed. It also studies the safety of this approach compared with standard care.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT05539729RecruitingPhase 1
Testing vancomycin for newly diagnosed multiple sclerosis
This Phase 1 study tests whether the antibiotic vancomycin can be given safely to people with newly diagnosed multiple sclerosis (or related early stages). It mainly focuses on safety and side effects, and whether the approach is feasible for this group.
New York, New YorkAges 18–50 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05539781Recruiting
Blood flow and brain function monitoring after carotid procedure
This trial studies how blood flow and brain function change after a carotid artery revascularization procedure (opening a narrowed carotid artery). It may help doctors understand what to expect after treatment, especially in people with significant artery narrowing.
Beijing, Beijing MunicipalityAges 18–85 - NCT05540262Recruiting
Edaravone for new anti-AQP4 optic neuritis
This trial tests edaravone, a medicine intended to reduce damage from optic neuritis, in adults whose condition is confirmed by a positive blood test for anti-AQP4 antibodies. It may help people who are in the first month after their first episode to preserve or improve vision.
NanningAges 18–70 - NCT05541250RecruitingPhase 1
Stem-like nerve cell treatment for severe nerve injuries
This Phase 1 study tests whether adding a patient’s own nerve support cells to a severely injured nerve is safe and helpful. It’s for people with recent major nerve damage in an arm or leg, with strict safety checks.
Miami, FloridaAges 18–65 - NCT05543681RecruitingPhase 2
Study drug for agitation in Alzheimer’s dementia with caregiver support
This Phase 2 trial tests a study medicine to reduce “agitation” behaviors in people with Alzheimer’s dementia. You and your caregiver would complete required assessments and may need genetic and blood testing to check how the body handles the drug.
Maitland, FloridaAges 60 years+ - NCT05543447Recruiting
Safety and effectiveness of a brain blood-vessel device for aneurysms
This study tests how safe and effective the DERIVO 2heal device is for treating an intracranial (brain) aneurysm. You may be a candidate if you’re an adult with an aneurysm that doctors plan to treat with this specific device and you can safely take anti-platelet medicines.
AugsburgAges 18 years+ - NCT05545007Recruiting
Pre-op vs post-op focused radiation for large brain metastases
This study compares giving focused, high-dose radiation before surgery versus after surgery for people with large brain metastases. The goal is to see which timing works best to control the tumors and help neurological outcomes.
Brescia, BresciaAges 18 years+ - NCT05545605Recruiting
Sodium oligomannate to prevent thinking problems after stroke
This trial tests whether sodium oligomannate can help prevent or lessen memory and thinking problems that can happen after a first stroke. It may help people who are recently hospitalized for ischemic stroke and have mild cognitive decline risk.
Guangzhou, BaiyunAges 18–80 - NCT05546138Recruiting
Study for early diabetic nerve damage in people with diabetes
This trial looks for and studies early nerve problems in the feet or legs that can happen with diabetes, before nerve damage is clearly diagnosed. It may help doctors better predict who is at risk and understand early changes.
AalborgAges 18–60 - NCT05546996Recruiting
Study of pressure readings from existing brain drains
This study collects brain pressure measurements using an external ventricular drain you may already have. It may help researchers better understand how these drains and pressures relate.
Houston, TexasAges 1–21 - NCT05549024RecruitingEarly Phase 1
PET/CT scan study for certain prostate, brain, or breast cancers
This early-phase study tests special PET/CT scans using a radioactive tracer to see cancer areas that have specific targets. It may help doctors better visualize tumors and plan next steps, using scans that you may already be familiar with (FDG) plus targeted tracers.
BeijingAges 18 years+ - NCT05548322Recruiting
Testing touch feedback for prosthetic limbs in healthy people
This study tests how well a prosthetic touch system can give realistic sensory feedback. It aims to improve how prosthetic users feel touch and movement, based on controlled testing in volunteers.
MarseilleAges 20–70 - NCT05548530Recruiting
Comparing outcomes after brain bleeding from different causes
This study looks at people with bleeding inside the brain to see how different treatment choices are linked to recovery. It may help doctors choose the most effective approach for patients with similar bleeding patterns.
Guiyang, GuizhouAges 18–80 - NCT05549258RecruitingPhase 2
Inebilizumab for children with NMOSD who had recent relapses
This trial studies whether inebilizumab can reduce illness activity in children with neuromyelitis optica spectrum disorder (NMOSD), a condition that can cause attacks affecting the eyes and spinal cord. It focuses on kids who have had recent relapses, meaning symptoms came back or worsened.
La Jolla, CaliforniaAges 2–17 - NCT05550155Recruiting
TMS treatment to reduce voices in schizophrenia
This trial studies whether repeated noninvasive brain stimulation (TMS) can help reduce ongoing voice-hearing (auditory verbal hallucinations) in people with schizophrenia or schizoaffective disorder. It focuses on whether doing this after medication is already adjusted can improve symptoms and help keep them controlled.
CaenAges 18–65 - NCT05550077Recruiting
Imaging study for narrowed brain arteries after stroke
This trial uses a detailed eye/brain imaging test (optical coherence tomography) to study people with significantly narrowed brain arteries after certain stroke-like events. It may help researchers better understand and monitor this condition to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05550714Recruiting
Choosing anesthesia type during deep brain stimulation for Parkinson’s
This study compares different anesthesia choices during deep brain stimulation surgery for Parkinson’s disease, using a technique that guides electrode placement. It may help your care team choose the safest and most comfortable anesthesia approach for surgery.
BeijingAges 50–80 - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05553353Recruiting
Repeated brain stimulation for depression after spinal cord injury
This study tests a non-drug treatment called repeated transcranial magnetic stimulation (rTMS) to reduce depression symptoms in people with depression after a spinal cord injury. You might be eligible if you have ongoing major depression and can safely receive magnetic pulses to the head.
Charleston, South CarolinaAges 18–60 - NCT05553457Recruiting
Active hand brace study for C6–C7 spinal cord injury
This trial tests an active hand brace designed to help people with C6–C7 spinal cord injury improve hand and finger movement. It may help with daily hand use by training and supporting weaker motor control after injury.
New York, New YorkAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.