Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT06862297Recruiting
Comparing a new jaw tracking device to standard sleep study for sleep apnea
This study compares a new device that tracks jaw movement during sleep to the standard sleep study (polysomnography) for diagnosing sleep apnea. You may be eligible if you have symptoms like loud snoring or daytime sleepiness and have been referred for a sleep study.
TaipeiAges 20–75 - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT06482502Recruiting
Testing arm function in Parkinson's with a ring and board test
This study checks if a 6-minute pegboard and ring test is a valid way to measure arm function in people with Parkinson's. It may help find better ways to track arm movement issues.
IstanbulAges 45–75 - NCT06601127RecruitingPhase 2
Tiprogrel for recent minor stroke or high-risk TIA
This trial tests a new anti-platelet drug called Tiprogrel to prevent another stroke in people who recently had a minor stroke or a transient ischemic attack (TIA) with certain artery narrowing or plaques. It aims to see if this medicine is safe and works better than current treatments.
Shenyang, LiaoningAges 40 years+ - NCT06660719RecruitingPhase 3
New stroke medicine SP-8203 with clot-busting therapy
This trial tests a new medicine called SP-8203 added to standard clot-busting treatment for people having a moderate to severe stroke. The goal is to see if it helps improve recovery and is safe.
BusanAges 19–85 - NCT06842095Recruiting
Stimulation therapy for stroke recovery
This trial tests if a non-invasive brain stimulation technique can improve arm movement recovery after a stroke. It is for people who had a stroke affecting their arm and are at least 3 months past the stroke.
OxfordAges 18 years+ - NCT07332299Recruiting
Brain stimulation and training for seniors with TBI
This study tests if a wearable brain stimulation device (tDCS) combined with computer-based training can improve attention and concentration in older veterans with a history of mild brain injury. It involves several sessions from home using a headset and computer.
Minneapolis, MinnesotaAges 65 years+ - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT07324915Enrolling by invitation
Buzzy Bee study for reducing pain during numbing shots in kids
This trial tests if a vibrating cold device called Buzzy Bee can help reduce pain when children receive a numbing shot in the mouth for dental treatment. It may help make the experience less scary and more comfortable for kids.
Jizan, Jazan RegionAges 7–9 - NCT07327775Recruiting
ADHD and fibromyalgia in mothers
This study looks at how having fibromyalgia affects mothers who also have a child with ADHD. It compares them to mothers of children without ADHD to see if the burden of care is different.
EdirneAges 18–50 - NCT07328451RecruitingPhase 1
Study of DNL628 for people with early Alzheimer's disease
This trial tests an experimental drug, DNL628, to see if it is safe and how it affects people with early Alzheimer's disease. It may help slow the disease by targeting a specific process in the brain.
's-HertogenboschAges 18–75 - NCT07325292RecruitingPhase 3
Frexalimab injection vs IV for multiple sclerosis
This study tests if a new injection (frexalimab) works as well as the IV version for people with relapsing or certain types of secondary progressive multiple sclerosis. It could offer a more convenient way to receive this treatment at home.
Cullman, AlabamaAges 18–60 - NCT07324837RecruitingPhase 3
Study of a clot-busting drug for stroke up to 24 hours later
This trial tests a single dose of a new clot-dissolving medicine for people who had a stroke 4.5 to 24 hours ago. It may help if you cannot have standard treatments like a clot-removal procedure or other clot-busting drugs.
Ryazan, Ryazan OblastAges 18 years+ - NCT07331272RecruitingPhase 1
CAR T-cells for lupus and myositis
This trial tests a new treatment using your own immune cells (CAR T-cells) targeted at a marker called CD19. It is for people whose lupus or myositis has not been controlled by other treatments.
Bengbu, AnhuiAges 18–70 - NCT07326423Enrolling by invitation
Imagery therapy app for autism language skills
This trial tests a computer program that uses mental imagery exercises to help young children with autism improve their language and learning skills. It is designed for children ages 2 to 5.
Foz do Iguaçu, ParanáAges 2–5 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Phoenix, ArizonaAges 45–75 - NCT07326709RecruitingPhase 3
Votoplam for Huntington's disease: a Phase 3 study
This study tests an investigational drug called Votoplam for people with Huntington's disease. It aims to see if the drug can slow progression of symptoms like movement and thinking problems.
Birmingham, AlabamaAges 21–70 - NCT07331285Recruiting
Genio therapy study for moderate to severe sleep apnea
This trial studies a device called Genio that is implanted to help keep your airway open while you sleep. It is for people with moderate to severe sleep apnea who have not been helped by other treatments.
Miami, FloridaAges 22 years+ - NCT07332702Recruiting
Spinal muscular atrophy gene study
This study looks at changes in two genes, SMN1 and SMN2, which are linked to spinal muscular atrophy (SMA). It aims to better understand the different versions of these genes in healthy people and those with SMA. Participating involves a blood sample and genetic analysis.
RouenAges 18 years+ - NCT07333586Recruiting
Insomnia treatment for better insulin sensitivity
This study tests whether treating insomnia can improve how your body uses insulin (a hormone that controls blood sugar). It may help people with excess weight and poor sleep who are at risk for diabetes.
Columbia, MissouriAges 18–50 - NCT07325305Recruiting
Exercise to protect muscle in childhood leukemia
This trial tests whether starting physical activity and exercise early in treatment can help children with leukemia prevent muscle loss and reduce frailty. It involves wearing a Fitbit to track activity and may help kids stay stronger during and after treatment.
Melbourne, VictoriaAges 5–17 - NCT07328360Recruiting
High-power laser for outer thigh nerve pain
This study tests whether a special high-power laser can reduce nerve pain on the outer thigh (called meralgia paresthetica). It's for people who have had this pain for at least 3 months and are not on blood thinners or pregnant.
UşakAges 18–65 - NCT07325487Recruiting
Brain stimulation for walking and balance in SCA6 ataxia
This study tests a new kind of deep brain stimulation that adjusts automatically to improve balance and coordination in adults with SCA6, a genetic form of ataxia. It may help patients who can still walk but have moderate to severe symptoms.
Gainesville, FloridaAges 21–89 - NCT07332442RecruitingPhase 3
CPAP and arousal in new sleep apnea patients
This study tests whether a common sleep apnea treatment (CPAP) affects how easily you wake up and the reasons behind it. It is for people who have just been diagnosed with sleep apnea and are not taking certain sleep medications or alcohol.
North Haven, ConnecticutAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.