Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05613608RecruitingPhase 2/Phase 3
Cannabidiol (CBD) study for alcohol use disorder
This trial tests whether cannabidiol (CBD) can help people cut down or quit drinking alcohol. It enrolls adults diagnosed with alcohol use disorder and wanting to reduce drinking, while checking for safety and other mental health or drug use factors.
Aurora, ColoradoAges 21 years+ - NCT05614193Recruiting
Deep imaging study for suspected stroke patients
This trial studies an advanced way to analyze CT or MRI scans for people who may have had a stroke or reduced blood flow to the brain. It aims to improve how scans are interpreted and shared for better care.
Beijing, Beijing MunicipalityAges 18–100 - NCT05614310Recruiting
Brain scan study to spot early Alzheimer’s
This study uses MRI brain scans and memory tests to help detect early Alzheimer’s disease. It compares people with Alzheimer’s (diagnosed by a clinician) with people without memory problems to see which scan and test results stand out.
AberdeenAges 18 years+ - NCT05615766Recruiting
Robotic arm exoskeleton rehab for people with arm weakness
This trial tests a robotic device that helps move your arm and hand during rehabilitation, with the goal of improving elbow and hand function. You may be a good fit if you have certain nerve/spinal cord injury levels and can still make some finger and elbow muscle movements at the start.
LondonAges 18 years+ - NCT05617365RecruitingPhase 1/Phase 2
Study treatment for chronic neck-related head and neck pain
This early-stage study tests a new treatment for people (women) who have long-lasting headaches and pain coming from the neck. It may help reduce symptoms, but you must match specific safety and diagnosis requirements.
East Lansing, MichiganAges 18–65 - NCT05617898Recruiting
Study how social rewards work in early schizophrenia
This study looks at how your brain learns from positive social experiences in people who are in the early stages of schizophrenia-type illness. It may help researchers understand “social anhedonia” (feeling less pleasure or reward from social situations) and guide future treatments.
Birmingham, AlabamaAges 18–35 - NCT05618054Recruiting
Explaining nerve signals in teens with POTS
This study looks at how a specific brain–vagus nerve connection works in people with POTS and tries to understand what happens over time. It may help researchers better explain symptoms and other health problems that can occur with POTS.
Richmond, VirginiaAges 12–21 - NCT05618002Recruiting
Study compares sleep medicines for chronic pain insomnia
This trial tests different treatments to help people with long-term (chronic) pain and severe insomnia sleep better. It’s looking at three options—one medicine (lemborexant) compared with existing sleep medicines (zopiclone and clonidine)—and whether they improve sleep when non-medicine sleep strategies haven’t worked.
Surrey, British ColumbiaAges 20–99 - NCT05618990Recruiting
Trying optimized MRI scans for clearer imaging
This study tests improved MRI scan settings to get clearer images. You may be able to take part if you’re able to safely have an MRI and you meet basic study consent and contraception rules.
ParisAges 18 years+ - NCT05619068Recruiting
Study tracking outcomes in Moyamoya disease
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
Beijing, Beijing MunicipalityAges 10–60 - NCT05619900Recruiting
Register people with lysosomal storage diseases
This study is a registry that collects information from people diagnosed with lysosomal storage diseases. It helps researchers better understand these conditions and support future studies.
San Francisco, CaliforniaAges Up to 64 years - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70 - NCT05620940RecruitingPhase 1
IV drug safety and absorption study in healthy men
This Phase 1 study tests two experimental medicines given by IV to healthy men. It checks safety and how the body absorbs and processes the drugs (their “pharmacokinetic” profile).
Herston, QueenslandAges 18–55 - NCT05621460Recruiting
Water carbonation and how well you tolerate standing up
This study tests whether drinking carbonated (fizzy) water changes how well your body handles standing up without feeling faint. If you are healthy and don’t have certain heart or nerve problems, you may be able to take part.
Burnaby, British ColumbiaAges 19–50 - NCT05622344Recruiting
Neurofeedback training to improve balance in vestibular schwannoma
This study tests whether brain “neurofeedback” training, along with a balance rehab plan, can help people with dizziness/balance symptoms from unilateral vestibular schwannoma. You may qualify if you can follow the study schedule and safely move your head and walk during testing.
Baltimore, MarylandAges 21–70 - NCT05622409Recruiting
Tissue and genetic data registry for diffuse glioma in adults
This study collects tumor tissue and basic medical information to better understand the genes involved in adult diffuse glioma. It may help future treatments by building a detailed research database and matching patients to study arms.
Kaohsiung CityAges 20 years+ - NCT05622461Recruiting
Recovery support program for children after traumatic brain injury
This trial supports families during the early weeks after a child’s brain injury and hospital stay. It aims to help caregivers and children move toward recovery with better support after discharge.
Cincinnati, OhioAges 18 years+ - NCT05623111RecruitingPhase 2
Nerve-area Botox shots for diabetic foot nerve pain
This Phase 2 trial tests whether injecting incobotulinumtoxin-A near painful nerves can reduce nerve-type pain in the feet for people with diabetes. If you have lasting, fairly symmetrical pain in both feet, the injections may help calm the nerve pain signals.
Glostrup MunicipalityAges 18 years+ - NCT05623137Recruiting
Acu-TENS to improve sleep after stroke
This trial tests a non-drug treatment (Acu-TENS) that uses gentle electrical stimulation on the skin to improve sleep in people who had a stroke. It may help if you have ongoing poor sleep and meet the age, walking, thinking, and health-skin safety requirements.
Hong KongAges 55–85 - NCT05623124Recruiting
Alzheimer’s and dementia brain and memory study with caregiver support
This is a study that enrolls people with mild Alzheimer’s-related memory problems or dementia to help build a research “neurobank.” It also involves memory testing and may include brain scans, with a stable caregiver to support follow-up.
Shanghai, Shanghai MunicipalityAges 50–90 - NCT05624138RecruitingPhase 3
Ketotifen to help prevent nerve damage from oxaliplatin
This trial tests whether ketotifen can protect against nerve damage (called peripheral neuropathy) caused by oxaliplatin, a common chemotherapy used for stage III colon cancer. If it works, it may help reduce tingling, numbness, or burning pain in the hands and feet.
Tanta, OtherAges 18 years+ - NCT05625438Recruiting
Home video therapy for early arm recovery after stroke
This study tests a home-based (telerehabilitation) program to help people practice arm movement after a recent stroke (or certain brain injuries). It may help improve arm function when started soon after symptoms begin.
Fullerton, CaliforniaAges 18 years+ - NCT05626296Recruiting
Blood-sample study of stroke patterns using multiple tests
This study looks at blood and lab “molecular” patterns in people who have had an ischemic stroke (a blocked blood vessel). It aims to understand differences between people labeled as having “phlegm-heat syndrome” versus not, which may help future stroke care. You may be eligible if your stroke was recent and confirmed by MRI.
Beijing, Beijing MunicipalityAges 50–80 - NCT05626894RecruitingPhase 2
Wrist sensor app to help use the weaker arm at home
This Phase 2 study tests a new wrist sensor system that tracks arm movement and gives feedback using a phone or tablet. It aims to improve daily use of the weaker (hemiparetic) arm in people with a prior stroke.
Boston, MassachusettsAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.