Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05626608Recruiting
Directional brain stimulation for Parkinson’s tremor and movement control
This trial tests a continuous electrical brain stimulation device placed in a deep brain area to help Parkinson’s symptoms—especially tremor and trouble with movement. It may help improve daily function and reduce periods when medicine does not work well.
Montpellier, FranceAges 18–70 - NCT05626816Recruiting
Genital nerve stimulation to improve bowel control after spinal injury
This trial studies whether stimulating nerves near the genitals (a gentle electrical stimulation approach) can improve bowel function in people with spinal cord injury. It may help bowel control when bowel dysfunction is caused by nerve injury.
Cleveland, OhioAges 18 years+ - NCT05627440Recruiting
Protein diet program to improve muscle strength in heart failure
This trial tests whether adding dietary protein can help skeletal muscles recover and function better in people living with heart failure. It may help with strength, muscle wasting, and overall ability to do daily activities.
Boston, MassachusettsAges 18–100 - NCT05628324Recruiting
Game-based training using muscle signals after stroke
This trial tests whether an EMG-controlled computer game can help retrain how your arm muscles activate after stroke. It may help improve upper-limb movement by practicing with real-time muscle feedback.
Charleston, South CarolinaAges 18 years+ - NCT05629000Recruiting
Study of treatment planning after carotid artery narrowing
This study looks at an approach to better plan treatment for people with significant narrowing of the carotid artery (the main artery to the brain). It may help doctors choose safer, more effective care after surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT05629559RecruitingPhase 1/Phase 2
Study drug 4D-310 for Fabry disease with heart problems
This Phase 1/2 study tests how safe and potentially effective 4D-310 is for adults with Fabry disease who have heart involvement. It may help people who can’t tolerate standard treatments like enzyme replacement therapy (ERT) or migalastat, or who still have disease progression.
MelbourneAges 18–65 - NCT05629702RecruitingPhase 2
Temozolomide with or without cannabinoids for recurrent brain tumor
This trial tests whether adding cannabinoid medicine to temozolomide helps people whose glioblastoma (GBM) has returned. It compares temozolomide plus cannabinoids versus temozolomide alone, using blinded treatment so neither you nor the team knows which option you get.
Bodelwyddan, DenbighshireAges 16 years+ - NCT05630586RecruitingPhase 2
Semaglutide shot for early stroke recovery
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
AarhusAges 18 years+ - NCT05632419Recruiting
Study of extreme agitation and what it predicts
This trial looks at people who show “extreme agitation” in order to better predict what may happen next. It mainly involves observation to understand the possible causes and likely outcomes of severe agitation.
Bobigny, Île-de-France RegionAges 18 years+ - NCT05632757Recruiting
Studying support for ALS patients and their family caregivers
This study looks at how much burden (stress and day-to-day strain) ALS creates for both the patient and the main caregiver. It may help shape better ways to support families facing ALS over time.
MarseilleAges 18 years+ - NCT05632978Recruiting
Study of epilepsy using real-world patient data
This is an observational study that looks at how epilepsy is diagnosed and how people do over time, using information from routine care. It may help doctors better understand epilepsy biology and outcomes using real-world data.
CardiffAges 16 years+ - NCT05633693Recruiting
Exercises to help children with fainting and blood-pressure drops
This study tests whether teaching special standing/balance movements can reduce fainting episodes in children who have recurring vasovagal fainting or certain forms of POTS. It may help your child feel more stable when standing and improve symptoms, while researchers measure balance and “counterpressure” responses during the tests.
Burnaby, British ColumbiaAges 6–18 - NCT05633875Recruiting
MRI study to better understand worsening in multiple sclerosis
This study uses detailed imaging (mostly MRI) to look for patterns that may explain why multiple sclerosis can worsen. It may help researchers understand the biology behind neurodegeneration and improve future care.
ParisAges 18 years+ - NCT05634356Recruiting
Study of how early speech learning changes with social input
This study looks at how infants learn speech sounds through everyday social interaction, like parent talk. It may help researchers understand what supports early speech development, including in babies with typical hearing and those with hearing loss or hearing devices.
Los Angeles, CaliforniaAges 7 months–2 years - NCT05634967Recruiting
Kesimpta pregnancy registry for pregnant people with MS
This registry collects information about pregnancy outcomes in people with multiple sclerosis (MS) who have taken Kesimpta (ofatumumab) during pregnancy or shortly before it. It may help doctors better understand safety and developmental outcomes for babies.
La Jolla, CaliforniaAges 18–100 - NCT05636748Recruiting
Study how blood clots affect stroke, using special scans
This study looks at how blood clots form and contribute to an acute ischemic (clot-related) stroke. It uses PET-CT scanning to better understand the process and may help improve how future stroke treatments are targeted.
EdinburghAges 18 years+ - NCT05636618RecruitingPhase 1/Phase 2
Targeted radiation for certain receptor-positive tumors
This trial tests a targeted form of radiation made to stick to specific “somatostatin receptor” markers on tumors. It is designed for people with advanced, receptor-positive neuroendocrine tumors or meningioma who may have had prior treatments and need more options.
Jacksonville, FloridaAges 18–90 - NCT05637086RecruitingPhase 2
Test pentoxifylline plus celecoxib for grand mal epilepsy on phenytoin
This Phase 2 study tests whether adding two medicines—pentoxifylline and celecoxib—to current phenytoin treatment is safe and may help people with grand mal (generalized) epilepsy. It focuses mainly on safety while you stay on a single epilepsy medicine.
Al MansurahAges 18–75 - NCT05637294Recruiting
Compare night-only versus full-time splinting for carpal tunnel
This study looks at whether wearing a wrist splint only at night works as well as wearing it full-time for carpal tunnel syndrome (CTS). It may help you find the most helpful and practical splint schedule to reduce symptoms.
HelsinkiAges 18 years+ - NCT05638191Recruiting
Nerve transfer surgery for arm grasp after neck spinal cord injury
This study looks at whether nerve transfer surgery can help restore hand grasp function after a neck (cervical) spinal cord injury. You may be eligible if your injury is recent and you meet specific strength patterns and can commit to rehabilitation after surgery.
Vancouver, British ColumbiaAges 18–70 - NCT05638269Recruiting
Study of gut bacteria in people with serious long-term illness
This study looks at the types of gut bacteria in people living in certain parts of China who have serious long-term (chronic) illnesses. The goal is to better understand how gut bacteria differ and may help doctors in the future tailor care.
Chaoyang, Beijing MunicipalityAges 18–75 - NCT05638464Recruiting
Brain stimulation to help hand movement after stroke
This trial studies whether a noninvasive brain stimulation technique can improve hand and arm function in people whose stroke happened more than 12 months ago. It may help if you have mild-to-moderate hand weakness and can follow training instructions.
Hong KongAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.