Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07224269RecruitingEarly Phase 1
Terazosin for energy levels in ALS
This study tests whether a blood pressure medicine called terazosin can boost energy production in cells of people with ALS, potentially slowing the disease. It involves taking the medication daily for a period and monitoring safety and effects.
Iowa City, IowaAges 18–80 - NCT07503444RecruitingPhase 3
Fenfluramine for Rett syndrome symptoms
This study tests whether fenfluramine, a medication already used for seizures, can help people with Rett syndrome. It aims to see if it improves daily life and reduces symptoms.
Little Rock, ArkansasAges 5–35 - NCT07768579Recruiting
Sequential treatment for Alzheimer's disease
This study tests a sequence of treatments to see if they can help people with Alzheimer's disease or mild cognitive impairment. It aims to slow down memory decline and improve daily function.
Beijing, Beijing MunicipalityAges 55–85 - NCT07766980Recruiting
Nutritional supplement for quality of life in Duchenne muscular dystrophy
This study tests whether a daily nutritional supplement called VM100 can improve quality of life for people with Duchenne muscular dystrophy. If you are 8 or older and your medications have been stable for at least 3 months, you may be able to participate.
Gainesville, FloridaAges 6 years+ - NCT06704334RecruitingPhase 4
Ginkgo and Huperzine with electrical stimulation for brain injury cognitive problems
This study tests whether a combination of Ginkgo Leaf Dropping Pills, Huperzine A injection, and median nerve electrical stimulation can improve cognitive function in people who have thinking or memory problems after a brain injury. The trial aims to see if this treatment is safe and effective compared to standard care.
Ganzhou, JiangxiAges 18–80 - NCT07139990RecruitingPhase 1
Personalized radiotherapy for lung, brain, sarcoma, or head and neck cancers
This trial tests whether giving personalized radiotherapy alongside standard treatments can better control several types of cancer: small cell lung cancer, brain metastases, soft tissue sarcoma, and head and neck cancer. It aims to see if this approach helps patients live longer without their cancer growing or coming back.
Dallas, TexasAges 18 years+ - NCT07768761Recruiting
Electrical stimulation exercise for lower limb paralysis
This trial tests whether a muscle exercise program using electrical stimulation can help people with paralysis in their legs. It may improve muscle strength, blood flow, or other health benefits.
Cleveland, OhioAges 18 years+ - NCT06221020Recruiting
Enhanced recovery after pituitary tumor surgery
This study tests a standard care plan to help patients recover faster after surgery to remove a pituitary tumor. It may reduce hospital stay and improve recovery.
Kaohsiung CityAges 20–75 - NCT07149870Recruiting
Pain management team for veterans with chronic pain
This study is testing whether a team-based pain management approach helps veterans with chronic pain and long-term opioid use. It aims to improve function and safety by addressing opioid concerns.
Birmingham, AlabamaAges 18 years+ - NCT07040449Recruiting
Stress and pleasure study for young teens
This study looks at how stress affects mood and the brain in teenagers aged 13 to 15. It involves brain scans and other tests to better understand teen mental health.
Chapel Hill, North CarolinaAges 13–15 - NCT00305305Recruiting
Brain development study for rare brain conditions
This study looks at how the brain develops in people with certain rare conditions that affect brain structure. It may help researchers understand these conditions better and could lead to improved care.
San Francisco, CaliforniaAges Any age - NCT06482268RecruitingPhase 1
Cell transplant for advanced parkinson's disease
This trial tests a new type of cell transplant for Parkinson's disease. The cells are made from stem cells and are meant to replace damaged brain cells that produce dopamine, which may improve your motor symptoms.
La Jolla, CaliforniaAges 40–75 - NCT05511363RecruitingPhase 3
Study of a new medicine for psychosis in Alzheimer's disease
This trial tests a new drug called KarXT to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease. If you or a loved one has Alzheimer's and experiences these symptoms, this study might offer a new treatment option.
Homewood, AlabamaAges 55–90 - NCT07767981Recruiting
Gut bacteria and side effects of precise radiation therapy
This study looks at how the bacteria in your gut might affect side effects from a precise type of radiation therapy called stereotactic radiosurgery. By collecting samples, researchers hope to find ways to reduce side effects in the future.
Chicago, IllinoisAges 18 years+ - NCT01467869Recruiting
Male fertility study for men with spinal cord injury
This study looks at fertility (the ability to father a child) in men who have a spinal cord injury. It compares them with healthy men to understand how spinal cord injury may affect fertility.
Miami, FloridaAges 18–50 - NCT07759115Recruiting
Music program to improve thinking in people with multiple sclerosis
This study tests a music-based program to see if it can help improve thinking and memory in people with multiple sclerosis. It is a small feasibility study to see if the program is practical and helpful.
Austin, TexasAges 18–80 - NCT07354724RecruitingPhase 1
Study of DNL952 for adults with late-onset Pompe disease
This trial tests a new drug, DNL952, in adults with late-onset Pompe disease. It aims to see if the drug is safe and how it works in the body, with different groups for people currently on enzyme replacement therapy or those who haven't had it in the past year.
Irvine, CaliforniaAges 18–75 - NCT07010705Recruiting
Digital measures for Huntington's disease trials
This study uses smartphone and wearable sensors to track movement and thinking in people with Huntington's disease. It aims to find better ways to measure how the disease progresses in clinical trials.
Rochester, New YorkAges 25–65 - NCT07087951Recruiting
Sound therapy for memory loss in older adults
This study tests whether listening to a special sound (gamma-frequency tones) can help slow down memory loss in older adults. It's for people who have mild memory problems but not dementia or other brain disorders.
Taoyuan, GuishanAges 60 years+ - NCT07066826RecruitingPhase 2/Phase 3
Huperzine A for mild-to-moderate Alzheimer's dementia
This study tests whether Huperzine A controlled-release tablets can help improve memory and thinking in people with mild-to-moderate Alzheimer's disease. You'll take the tablets or a placebo to see if it slows down dementia symptoms.
BeijingAges 50–85 - NCT07696741Recruiting
Pain Reprocessing Therapy for Chronic Lower Back Pain
This study tests a type of talk therapy called pain reprocessing therapy (PRT) for adults with chronic lower back pain. The goal is to see if PRT can help reduce pain and improve quality of life.
Toronto, OntarioAges 18–65 - NCT04804241RecruitingPhase 2
Senicapoc for early Alzheimer’s symptoms
This Phase 2 study tests whether the drug senicapoc can slow or improve symptoms in people with early Alzheimer’s disease or mild memory impairment. You would have a 50/50 chance of getting senicapoc or a placebo (inactive pill), along with regular study visits and testing.
Sacramento, CaliforniaAges 55–85 - NCT07137624Recruiting
Can thinking about walking help MS patients?
This study tests whether imagining or watching walking movements can improve walking ability in people with multiple sclerosis. It focuses on low-risk, non-invasive mental exercises that may help retrain the brain and muscles.
AnkaraAges 18 years+ - NCT07752784RecruitingPhase 3
Tau brain imaging in people with mild thinking changes or Alzheimer's
This study uses a special PET scan to take pictures of abnormal tau protein in the brain. It aims to see if the scan results match what is found in brain tissue after death, which could help improve diagnosis of Alzheimer's and related conditions.
Beijing, Beijing MunicipalityAges 50 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.