Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT05092685RecruitingPhase 1/Phase 2
Gene therapy trial for children with OTC ammonia build-up
This early-phase study tests an AAV gene therapy meant to reduce ammonia levels in children with ornithine transcarbamylase (OTC) deficiency. It’s designed to slow or stop ammonia-related harm, while also carefully monitoring safety for years.
LondonAges birth–16 years - NCT05494034Recruiting
Monitoring heart rhythms after stroke to guide care
This study uses a small implantable heart monitor to track heart rhythm in people after an acute ischemic stroke or TIA. It aims to learn how often hidden heart rhythm problems show up, which could help doctors choose better stroke prevention treatments.
AthensAges 40–100 - NCT05908695RecruitingPhase 4
GV-971 treatment for mild to moderate Alzheimer’s disease
This Phase 4 trial tests whether a medicine called sodium oligomannate (GV-971) is safe and effective for people with mild to moderate Alzheimer’s disease. It may help slow or improve memory and thinking symptoms while carefully tracking side effects.
Huainan, AnhuiAges 50–85 - NCT06116942Recruiting
Brain stimulation and computer training for arm recovery after stroke
This trial combines magnetic brain stimulation with computer-based motor training to help improve arm and hand function in people who had a stroke at least 6 months ago. It may be a good fit if you have moderate to severe weakness on one side and can take part in brain-computer interface training.
Leipzig, SaxonyAges 20–80 - NCT06120426Recruiting
Surgery types and radiation for spinal tumors that have spread
This study compares two types of spinal surgery combined with radiation for people whose cancer has spread to the spine in a limited way (no more than 5 spots). It aims to find which approach better controls pain, tumor growth, and spinal stability.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06125236Recruiting
Stroke study for large artery blockages in Southwest China
This study is collecting information from people in Southwest China who have had a stroke caused by a blocked large or medium artery. The goal is to learn more about these strokes and how to treat them better.
LuzhouAges Any age - NCT06129656Recruiting
Cardiac Amyloidosis Registry at Leipzig Hospital
This study is a registry that collects information from people with cardiac amyloidosis. It helps doctors learn more about the condition and how to better treat it.
Leipzig, SaxonyAges Any age - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT06094855Recruiting
Cooling and balance in multiple sclerosis
This trial tests if cooling therapy can improve balance in people with multiple sclerosis. If you can stand without help for at least one minute, you may qualify.
New York, New YorkAges 18–75 - NCT06111898Recruiting
Understanding movement in infants at risk
This study looks at how the brain and body work together to control movement in infants who are at high risk for developmental issues. It may help find early signs of motor problems.
GenevaAges 8 months–1 year - NCT05698901Recruiting
Testing heart blood tests and scans to monitor Fabry disease
This study checks whether certain heart-related blood tests and heart scans can help monitor people with Fabry disease. It may be useful for both people who have never received enzyme replacement therapy and those who have.
TaipeiAges 18 years+ - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT05923905RecruitingPhase 4
Study of FB1006 for people with early ALS
This trial tests whether FB1006 is safe and works better than usual care for treating amyotrophic lateral sclerosis (ALS). It focuses on people with relatively early ALS and good breathing function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06145932Recruiting
Repetitive TMS for essential tremor
This trial tests whether repetitive transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to calm overactive brain cells — can help reduce shaking in people with essential tremor. If you have essential tremor and no metal implants or other brain conditions, you may be eligible to participate.
SuzhouAges 18–80 - NCT05908214Recruiting
Electrical stimulation for leg stiffness and overactive nerves
This study tests a treatment using high-frequency electrical stimulation to reduce overactive nerve signals that can cause stiff legs, poor ankle control, cramps, or restless legs. It may help improve movement and comfort during walking or at night, depending on the condition.
LausanneAges 18 years+ - NCT06131385Recruiting
Tracking IV clot-busting treatment for stroke in China
This study is tracking patients in southwestern China who have had an acute ischemic stroke and received a clot-busting medicine through an IV. It aims to learn more about how well this treatment works and how it is used in real-world settings.
LuzhouAges Any age - NCT06148285Recruiting
Hyperbaric oxygen for ischemic stroke recovery
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover after a recent ischemic stroke. It is open to stroke survivors admitted to Touro's inpatient rehab unit.
New Orleans, LouisianaAges 18 years+ - NCT05331118Recruiting
Study of complications and long-term outcomes after major surgery
This study follows people after planned, higher-risk surgery to learn what complications happen and how patients do long-term. It may help doctors predict risks and improve care for people having similar operations.
UtrechtAges 18 years+ - NCT04945603Recruiting
Study for poor-grade brain bleed from a ruptured aneurysm
This trial is enrolling people who come to the emergency room with a serious brain bleed caused by a ruptured brain aneurysm. It aims to test care strategies for patients with poor-grade injuries, who may have worse outcomes than typical cases.
BergamoAges 18 years+ - NCT05863910Recruiting
Real-world study of medical cannabis use in children
This study looks at how medical cannabis is used for children and teens in everyday life, by collecting information through online questionnaires. It may help doctors and families better understand which uses are common and how people experience them.
Winnipeg, ManitobaAges 3–17 - NCT06151002Recruiting
Remote assessment for people with Parkinson's
This trial tests a remote way to assess people newly diagnosed with Parkinson's disease, to help monitor their condition and guide care.
LondonAges 18–90 - NCT03137355Recruiting
Registry for people with Leigh syndrome
This study is a registry that collects information from people diagnosed with Leigh syndrome. It may help researchers understand the condition better and improve future care.
Houston, TexasAges birth–100 years - NCT03240965Recruiting
Testing changes in smell and taste after recent stroke
This study looks at how smell and taste may change after a new stroke, especially in the first few days. It may help doctors better understand and monitor symptoms related to eating and swallowing after stroke.
Giessen, HesseAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.