Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT04859270Recruiting
Rehab support for survivors after cardiac arrest
This study looks at a “whole-person” support plan for people who survived a non-traumatic cardiac arrest. It aims to improve the survivor’s health and also help support family members as they recover.
TaipeiAges 20 years+ - NCT07000214RecruitingPhase 2
Magnetic stimulation and balance training to prevent falls in diabetic nerve pain
This trial tests if adding a non-invasive magnetic stimulation treatment to balance exercises can reduce fall risk in people with type 2 diabetes who have nerve damage in their feet and legs.
Chon Buri, Changwat Chon BuriAges 50–75 - NCT06453915RecruitingEarly Phase 1
Brain PET scan for inflammation in fatty liver disease
This study uses a special PET scan to look for inflammation in the brain related to fatty liver disease. It may help researchers understand how liver health affects brain function.
Sacramento, CaliforniaAges 18 years+ - NCT07726082Recruiting
A group program to help with long-term fatigue
This study tests a new way to help people with long-term fatigue that gets in the way of daily life. It uses a group program that focuses on making small, helpful choices to feel better.
BaselAges 18–65 - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT04206215Recruiting
Noninvasive brain stimulation for carpal tunnel pain relief
This study tests whether a noninvasive brain stimulation treatment can reduce chronic carpal tunnel (CTS) pain, especially when pain spreads beyond the usual nerve area. If you have long-lasting CTS pain that hasn’t improved with standard treatments, you may be able to try this therapy while being closely monitored for safety.
Charlestown, MassachusettsAges 18–80 - NCT04312126Recruiting
How naps may improve motor learning after stroke or in healthy adults
This study tests whether taking a nap can improve how well people learn a movement task. It may help you understand how sleep affects “motor learning,” both in healthy volunteers and after stroke.
Bethesda, MarylandAges 18–80 - NCT07425275Recruiting
Study of a mouth care plan for dry mouth in diabetes
This trial tests a special mouth care plan to help people with diabetes who have dry mouth. The goal is to see if it improves comfort and mouth health.
Peshawar, KPKAges Up to 18 years - NCT07770139Enrolling by invitation
Online yoga and breathing for student stress relief
This study compares two online programs—one with yoga poses and breathing, the other adding a special breathing technique—to see if they help reduce stress and improve well-being in university students.
IstanbulAges 18–30 - NCT07575958Recruiting
Water Exercise for Muscle Loss in Adults Over 65
This study tests whether exercise in a swimming pool can help older adults rebuild muscle strength and mass. If you have age-related muscle loss (sarcopenia), this trial may help you regain strength and function.
Istanbul, IstanbulAges 65 years+ - NCT05586581RecruitingPhase 1/Phase 2
PET and MRI scans to study brain changes in treated HIV
This study uses PET and MRI scans, plus blood tests and memory/thinking questionnaires, to understand what drives brain problems in people living with HIV even during treatment. It may help researchers learn why symptoms happen and how treatment relates to brain function.
New Haven, ConnecticutAges 18–80 - NCT07744997Recruiting
Wellness product for better sleep and health
This study tests a health and wellness product for improving sleep and related health outcomes. It is a blinded study, meaning neither you nor the researchers will know if you receive the active product or a placebo until the study ends.
Del Mar, CaliforniaAges 21–105 - NCT07486934RecruitingPhase 3
Study of DYNE-101 for Myotonic Dystrophy Type 1
This trial tests an experimental drug called DYNE-101 to see if it can help people with myotonic dystrophy type 1 (DM1). The study aims to improve muscle function and daily life. It is for adults who can walk and stand up from a chair without help.
La Jolla, CaliforniaAges 16 years+ - NCT05267951Recruiting
Closed-loop spinal stimulation to improve hand use after spinal injury
This trial tests a smart form of spinal stimulation that responds to your body’s signals to help improve upper-extremity (arm/hand) function after a spinal cord injury. If it works, it may make everyday hand tasks like dressing, grooming, or feeding easier.
Seattle, WashingtonAges 21–70 - NCT07301125Enrolling by invitation
Tongue and mouth exercises for sleep apnea
This study tests if doing specific tongue and mouth exercises can help people with obstructive sleep apnea. If you have sleep apnea and are willing to pause other treatments for 3 months, you may be able to join.
Minneapolis, MinnesotaAges 18–65 - NCT06416072Enrolling by invitation
Blood marker study for people not eligible for Alzheimer's prevention trials
This study looks at blood markers in people who were part of an early Alzheimer's prevention study but did not qualify for it because their amyloid levels were too low. It aims to understand brain changes and possibly find ways to detect Alzheimer's even earlier.
Birmingham, AlabamaAges 55–80 - NCT05670496Recruiting
NIDCD medical data and sample collection for communication disorders
This study collects medical information and specimens to support research on problems with hearing, balance, taste, smell, voice, speech, and language. It may help you (or your child) get additional evaluation and follow-up through NIDCD, especially if your clinician thinks it could be useful.
Bethesda, MarylandAges 2–99 - NCT07549997RecruitingPhase 1
Social Participation Recovery Program After Brain Injury
This study tests whether a group program can help people who've had a traumatic brain injury (TBI) get back to social activities they enjoyed before their injury. You'll work with others and learn strategies to re-engage with friends, family, and community.
St Louis, MissouriAges 18 years+ - NCT06858579RecruitingPhase 3
Testing DNTH103 for chronic inflammatory demyelinating polyneuropathy (CIDP)
This trial tests a new drug called DNTH103 for adults with CIDP, a condition that affects nerves and causes weakness. It aims to see if the drug can help people who are currently on treatment, have tried treatment before, or are new to treatment.
Birmingham, AlabamaAges 18–75 - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05237973Recruiting
Neuromuscular ultrasound study for healthy people and patients
This study uses an ultrasound scan to look at muscles and nerves (including the breathing muscle). It may help researchers better understand neuromuscular problems and how well ultrasound can detect them.
Bethesda, MarylandAges 18–110 - NCT07771621Enrolling by invitationPhase 1
PET scan for detecting heart amyloidosis
This study tests a new PET imaging agent that may help doctors see amyloid buildup in the heart more clearly. It may help people with heart amyloidosis or those suspected of having it.
St Louis, MissouriAges 18 years+ - NCT07322887RecruitingPhase 2
Study of sul-238 for early untreated parkinson's disease
This study tests whether an experimental medicine called SUL-238 can improve energy levels in the brain cells of people with early, untreated Parkinson's. It uses a special type of MRI to see if the medicine affects brain energy.
GroningenAges 40 years+ - NCT07769281Recruiting
Recovering arm and hand movement after stroke
This study tests a new system called NeuroTechR3 that may help people who have had a stroke regain movement in their arm and hand. It involves training exercises that you can do at home with a computer.
Jacksonville, FloridaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.