Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT06857058Recruiting
Drug-eluting stent for brain artery narrowing
This trial tests a drug-coated stent to treat severe narrowing in brain arteries. It may help reduce the risk of stroke in people with hardened arteries in the brain.
ZhengzhouAges 18–80 - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT07245706Recruiting
Shoulder Health After Rehab and Performance Training
This study looks at how shoulder health changes after a rehabilitation and performance training program for people with paraplegia who use manual wheelchairs. It may help you strengthen your shoulders and prevent injuries as you start your life after rehab.
Nottwil, Canton of LucerneAges 18–70 - NCT07242300RecruitingPhase 3
Testing a new botulinum toxin for arm stiffness after stroke
This trial tests a new injectable medication (Eveotox) to see if it can safely reduce arm or hand stiffness in people who have had a stroke. The goal is to improve daily activities like dressing or cleaning your hand.
Bengbu, AnhuiAges 18–80 - NCT07240337Recruiting
Botox injections for arm and leg spasticity after stroke
This study looks at how well botulinum toxin (Botox) works for reducing muscle tightness in people who have weakness on one side of the body after a stroke. It will use medical records from before and after treatment to see if the injections improve function.
Istanbul, BahcelievlerAges 18–75 - NCT07248813Recruiting
Home-based rehab program for chronic low back pain
This trial tests a telerehabilitation program you can do from home using a smartphone or computer. It aims to improve function and reduce pain for people with chronic low back pain compared to usual care.
México, TexcocoAges 18–60 - NCT07248540Recruiting
IV magnesium for severe period pain
This trial tests whether an IV magnesium injection can quickly reduce severe period pain. If you have very painful periods without other underlying conditions, this study may help find better relief options.
Gaziosmanpaşa, Outside of the USAges 18–35 - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07241429Recruiting
Fear of movement and balance after stroke
This study looks at how fear of movement (kinesiophobia) affects balance in people who have had a stroke. It may help understand how to improve recovery.
IstanbulAges 18–80 - NCT07246577Recruiting
Improving diagnosis and monitoring in giant cell arteritis
This study uses ultrasound, a biopsy of the temple artery, and blood tests to improve how giant cell arteritis (GCA) is diagnosed, monitored, and predicted. It may help doctors find better ways to manage this condition.
GothenburgAges 18 years+ - NCT07246980Recruiting
Allay hydrogel cap safety monitoring study
This study monitors patients who receive the Allay hydrogel cap to check its safety and how well it works. It helps doctors learn more about this treatment.
Redwood City, CaliforniaAges Any age - NCT07241234RecruitingPhase 1
Study of an experimental drug for phenylketonuria (PKU)
This trial tests an investigational drug (AG-181) for people with PKU who have a specific genetic change (R408W mutation). It aims to check if the drug is safe and how it works in your body.
Indianapolis, IndianaAges 18–69 - NCT07240896RecruitingEarly Phase 1
Testing a new mRNA therapy for Wilson disease
This trial tests an experimental mRNA treatment (DSL101) for adults with Wilson disease. It's for people whose condition is stable on current therapy and who have certain genetic markers. The goal is to see if the new treatment can help the body process copper better and reduce the need for standard medicines.
Hefei, AnhuiAges 18 years+ - NCT07246564RecruitingPhase 4
Rozanolixizumab for Generalized Myasthenia Gravis in Chinese Adults
This study tests an investigational drug called rozanolixizumab for Chinese adults with generalized myasthenia gravis who have a specific antibody (AChR or MuSK) and symptoms that still affect daily activities. It aims to see if the drug helps improve muscle strength and quality of life.
BeijingAges 18 years+ - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT07243405Recruiting
Nerve stimulation for sleep breathing problems
This trial tests a nerve stimulation device for people with moderate to severe sleep-disordered breathing who cannot use or tolerate standard treatments. It may help you breathe better during sleep.
Panama City, Provincia de PanamáAges 18 years+ - NCT07244835RecruitingPhase 1
A study of DEG6498 for advanced solid tumors
This trial tests a new drug, DEG6498, for people with advanced solid tumors that have not responded to other treatments. It may be an option if your cancer has a BRAF mutation or is a type of liver cancer called HCC.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07241520RecruitingPhase 3
Testing SHPL-49 injection for recent stroke patients
This trial tests a new medication, SHPL-49, given as an injection to people who have just had a stroke caused by a blood clot (ischemic stroke). It is for patients who are already receiving standard clot-busting treatment within 8 hours of symptoms starting. The study will see if adding this drug helps improve recovery.
Linfen, ShanxiAges 18–80 - NCT07247279Recruiting
Study of myasthenia gravis treatments in Russia
This study tracks how generalized myasthenia gravis (a condition that causes muscle weakness) is treated in Russia. By looking at real-world data, researchers hope to learn more about which treatments work best for people like you.
Kazan'Ages 18 years+ - NCT06904989Recruiting
Helping foot nerve pain from chemo with shoe inserts
This trial tests whether special shoe inserts can reduce foot pain and numbness caused by chemotherapy for breast cancer. It may help you feel better and walk more easily.
GothenburgAges 18 years+ - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT06902168Recruiting
Diving and pool exercises for muscle tightness in kids with cerebral palsy
This study tests whether diving and swimming-type exercises can help reduce muscle stiffness and improve movement in young children with spastic cerebral palsy. It is for children ages 2 to 5 who have significant mobility challenges (GMFCS levels IV or V).
Banhā, BenhaAges 2–5 - NCT06900049RecruitingEarly Phase 1
Testing LE051 for boys with Duchenne muscular dystrophy (exon 51)
This study tests a new medicine called LE051 for boys with Duchenne muscular dystrophy (DMD) who have a specific genetic change that allows 'exon 51 skipping.' The goal is to see if it is safe and can help improve muscle function. Boys who join will be closely monitored for heart and lung health.
Shanghai, Shanghai MunicipalityAges 4–8 - NCT05233475Recruiting
Rehab program after concussion in Danish adults
This trial tests a “get going” rehabilitation program for people who recently had a concussion (mild brain injury) from a head impact. It may help reduce concussion symptoms and improve day-to-day functioning in the months after injury.
Hammel, Deb´nmarkAges 18–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.