Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05930145Recruiting
Two clot-retrievers versus one for acute stroke treatment
This trial compares using two clot-retrievers at the same time versus using just one to remove the clot in an acute ischemic stroke. It may help find a more effective approach to restore blood flow and improve recovery.
EssenAges 18 years+ - NCT05932589Recruiting
Study of brain signals as signs of Rett syndrome
This study measures brain and nerve activity (brain signals) to find patterns that match Rett syndrome. It may help researchers better track Rett changes over time and develop more precise ways to measure response in future treatments.
Los Angeles, CaliforniaAges 1–18 - NCT05934149Recruiting
Lupus health registry that stores samples for future research
This study keeps a long-term record of people with lupus (systemic lupus erythematosus) and collects samples so researchers can study the disease better. You may be able to join if you meet lupus diagnosis criteria, are not pregnant, and can follow the study visits and consent process.
Birmingham, AlabamaAges 18–110 - NCT05934188Recruiting
Study how gut signals relate to brain aging and diseases
This study looks at how the gut may influence the brain in normal aging and conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis. It may help researchers understand new ways to measure or treat these brain changes over time.
Venice-Lido, VeniceAges 20–90 - NCT05934747Recruiting
Parkinson’s trial for people with implanted brain stimulators
This study tests an approach to improving Parkinson’s symptoms in people who already have deep brain stimulation (DBS) devices. It focuses on patients who are able to do walking tests safely and confirm they can understand and consent.
Minneapolis, MinnesotaAges 18–85 - NCT05935241Recruiting
Program mPATH for sleep and activity in older adults
This trial tests a program (mPATH) to help older adults with sleep trouble by improving activity and exercise habits. It may be helpful if you have low income and want support building moderate exercise safely.
Baltimore, MarylandAges 65 years+ - NCT05935007Recruiting
Study for people with an Aveir DR leadless pacemaker
This study uses your medical records from Medicare to learn how the Aveir DR leadless pacemaker performs in everyday life after it’s implanted. It mainly helps researchers and doctors understand real-world outcomes and care needs.
Sylmar, CaliforniaAges 18 years+ - NCT05935722Recruiting
Home parenting support for parents of young children
This study tests a home-based parenting support program designed for parents who have learning or attention differences (like autism or ADHD). It aims to give tailored strategies to help you manage parenting daily challenges for children aged 0 to 9.
EnköpingAges Any age - NCT05935709Recruiting
Danish database study for GCA or PMR
This study builds and uses a Danish database for people diagnosed with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). It may help doctors learn more about these conditions over time and improve care.
AarhusAges 50 years+ - NCT05936034Recruiting
Hearing aid vs no hearing aid during platinum chemotherapy
This study compares how patients’ quality of life changes when people who have hearing loss from platinum chemotherapy use a hearing aid versus not using one. It may help understand whether hearing aids improve daily life during treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT05936619Recruiting
Brain-computer device for communication in people with paralysis
This trial tests a “brain-computer interface” that aims to help people with paralysis communicate. It involves surgery to place a device and uses frequent follow-ups, including daily help from a caregiver to watch the surgical area and behavior.
Dallas, TexasAges 18–65 - NCT05937685Recruiting
Lower blood pressure after a heart or stroke event
This trial tests ways to help lower blood pressure in people who have had a heart attack or stroke and are at higher risk for more problems. If your blood pressure is high, the program may help reduce risk by getting it under better control.
Downey, CaliforniaAges 35 years+ - NCT05938543Recruiting
Brain stimulation and appetite in Prader-Willi syndrome
This trial studies whether targeted brain stimulation (TMS) can help with appetite and eating feelings in people with Prader-Willi syndrome. It also includes an MRI scan to measure brain-related effects, but only if you can safely have these scans.
Belmont, MassachusettsAges 18–64 - NCT05939232Recruiting
Registry for X-linked adrenal and brain fat disease
This study collects health information and test results from people with X-linked adrenoleukodystrophy (X-ALD) and some genetic carriers. It helps researchers better understand the condition and how it varies, which can guide future care and studies.
BeijingAges 6–70 - NCT05939453Recruiting
Bright light therapy for Prader-Willi sleepiness
This trial studies whether daily bright light therapy can reduce sleepiness in people with Prader-Willi syndrome. It may help by improving daytime alertness, but you must meet specific sleepiness, eye-safety, and mental health criteria to join.
Brooklyn, New YorkAges 6–88 - NCT05939362Recruiting
7T MRI imaging study to predict Alzheimer’s progression
This study uses very high-strength MRI scans (7T) to look for brain imaging patterns that may predict how Alzheimer’s disease will progress. It may help doctors spot which changes are linked to faster or slower decline.
PoitiersAges 60–90 - NCT05939739Recruiting
Testing genes in severe language and learning difficulties
This study uses a special DNA test (trio exome sequencing) on a child or young adult and their two biological parents to look for a genetic cause of language and learning difficulties. If a genetic reason is found, it may help explain the cause and guide future care.
DijonAges 3–40 - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05940350Recruiting
Phone and video coaching after ischemic stroke
This study tests whether tele-rehabilitation coaching delivered by phone or online can help people recover and function better after an ischemic stroke. It may support safer, more consistent rehab guidance from home, tailored through coaching sessions.
AntalyaAges 45 years+ - NCT05940493RecruitingPhase 2
Abemaciclib for newly diagnosed grade 3 meningioma
This trial tests abemaciclib, a targeted medicine, to see if it can help people with newly diagnosed grade 3 meningioma after standard radiation treatment. It may help by slowing tumor growth or improving outcomes after initial therapy.
Phoenix, ArizonaAges 18 years+ - NCT05940584Recruiting
Video rehabilitation at home vs paper aftercare after hospital rehab
This study compares home “tele-rehabilitation” (video/online exercises) with a traditional paper-based aftercare program after you leave inpatient rehabilitation. It may help improve recovery in movement, sensation, thinking, swallowing, or speech by giving the right kind of support after discharge.
Vienna, State of ViennaAges 18–99 - NCT05942339Recruiting
Testing ARC-IM lumbar therapy to help walking after spinal cord injury
This study tests a therapy using an implanted spinal array and a lumbar system (ARC-IM) to support mobility in people with chronic spinal cord injury. It focuses on whether the approach is safe and may improve walking or movement over time.
Lausanne, Canton of VaudAges 18–65 - NCT05942716RecruitingPhase 2
Testing how serotonin changes impulsivity in Tourette
This Phase 2 study looks at whether changing serotonin activity can affect impulsivity and related brain function in people with Tourette disorder. You may be asked to continue aripiprazole and complete brain scans that test how your brain responds during tasks.
BronAges 18–65 - NCT05943002Recruiting
Track symptoms and life effects using a phone survey
This study uses patient-reported questionnaires and health/economics/psychosocial questions for people with Friedreich ataxia. It aims to better understand how the condition affects daily life and what outcomes matter most, which can help future care and research.
InnsbruckAges 12 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.