Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06137625Recruiting
Rhythm and dance learning in children with motor disorders
This study looks at how rhythm affects learning dance moves in children ages 8 to 16, both those with motor disorders (like cerebral palsy or developmental coordination disorder) and those without. It may help understand how to make movement therapy more effective.
ToulouseAges 8–16 - NCT06138132RecruitingPhase 1
CAR-T cell therapy for progressive multiple sclerosis
This trial is testing a type of immunotherapy called CAR-T cells (made from your own immune cells) to see if it can help slow or stop progressive multiple sclerosis. It is a very early safety study, so only people with progressive MS who meet strict health criteria can join.
Palo Alto, CaliforniaAges 18–65 - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06138639RecruitingPhase 1/Phase 2
Gene therapy SGT-003 for Duchenne muscular dystrophy
This trial tests a new gene therapy called SGT-003 for children with Duchenne muscular dystrophy. It aims to help the body produce a working version of dystrophin, the protein missing in Duchenne.
Little Rock, ArkansasAges birth–17 years - NCT06138925Recruiting
Walk study for children with cerebral palsy
This study looks at how children with cerebral palsy walk compared to healthy children. Researchers use small sensors to measure movement, and the goal is to better understand walking problems.
DijonAges 7–17 - NCT06139692RecruitingPhase 4
Comparing light sedation during clot removal for stroke
This study compares two types of light sedation (medication to help you relax) during a procedure to remove a blood clot in the brain after a stroke. The goal is to find which sedation method helps patients recover better.
Nanjing, None SelectedAges 18 years+ - NCT06140719Recruiting
Study to speed up DIPG and DMG research
This trial collects information from people with a rare type of brain tumor called DIPG or DMG. The goal is to help researchers learn more about these tumors and find better treatments faster.
Los Altos, CaliforniaAges Any age - NCT06140940Recruiting
Mental imagery study for people with and without aphantasia
This study compares how people who cannot create mental pictures (aphantasia) and people who can perform motor imagery tasks and undergo noninvasive brain stimulation.
BronAges 18 years+ - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT06142448Recruiting
Walking tricks for better gait in Parkinson's
This study tests whether using simple walking tricks (like stepping over lines or listening to a beat) can help people with Parkinson's improve their walking. If you haven't already been using these tricks daily, you may be able to join and see if they help you.
NijmegenAges 18 years+ - NCT06143488Recruiting
Clot removal vs. best medicine for mild stroke with large vessel blockage
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
Wuhu, AnhuiAges 18 years+ - NCT06144021Recruiting
Kefir whey drink for muscle health in adults over 40
This study tests whether a fermented milk drink (kefir whey postbiotics) can help improve muscle mass in people over 40 who have low muscle. It is for generally healthy adults who are not taking certain medications or following special diets.
SeoulAges 40 years+ - NCT06144151Recruiting
Pupil check to predict CAR-T brain side effects
This study tests if checking your pupil size with a small light device can predict brain-related side effects from CAR-T cell therapy. It is for patients with certain lymphomas receiving axi-cel CAR-T treatment in the hospital.
Houston, TexasAges 18 years+ - NCT06145516Recruiting
Sleep program to ease pain after joint replacement
This study tests whether a sleep program can help with pain after knee or hip replacement. If you have insomnia and arthritis pain, you may be able to join before your surgery.
Uppsala, UpplandAges 18–100 - NCT06145711Recruiting
Stem cell therapy for Parkinson's disease
This trial uses special stem cells (made from skin or blood cells) to replace damaged brain cells in people with Parkinson's. The goal is to see if these cells can improve movement and reduce symptoms.
Shanghai, Shanghai MunicipalityAges 30–70 - NCT06145932Recruiting
Repetitive TMS for essential tremor
This trial tests whether repetitive transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to calm overactive brain cells — can help reduce shaking in people with essential tremor. If you have essential tremor and no metal implants or other brain conditions, you may be eligible to participate.
SuzhouAges 18–80 - NCT06146010Recruiting
German leptomeningeal disease registry study
This study collects information from people with leptomeningeal disease, a condition where cancer spreads to the lining of the brain and spinal cord. By joining, you help researchers learn more about this disease and how it affects people.
BonnAges 18 years+ - NCT06146062RecruitingPhase 2
Stem cell therapy for severe traumatic brain injury
This trial tests whether a single infusion of stem cells from donated umbilical cord tissue can help calm inflammation in the brain after severe traumatic brain injury. It is for patients aged 18–50 who need brain pressure monitoring and are not responding to verbal commands 5 days after sedation is stopped.
ClamartAges 18–50 - NCT06146790Recruiting
Endovascular treatment for strokes in smaller brain arteries
This trial tests a minimally invasive procedure to remove blood clots from smaller arteries deep inside the brain. It may help people with moderate to severe stroke symptoms who can be treated within 24 hours of symptom onset.
Hefei, AnhuiAges 18 years+ - NCT06147258Recruiting
Writing to heal grief after a spinal cord injury
This study tests whether writing about your deepest emotions about your spinal cord injury can help you work through feelings of grief. You will write a few times over several weeks, and the study will see if it helps you feel better.
Birmingham, AlabamaAges 18 years+ - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06148077Recruiting
Manual therapy for head and neck cancer survivors with jaw or shoulder issues
This study tests whether manual therapy (hands-on treatment) can improve mouth opening, swallowing, and movement in people who had head and neck cancer surgery or radiation. It may help if you have jaw stiffness, pain, or shoulder problems after treatment.
Temuco, CautinAges 18 years+ - NCT06148051Recruiting
Australian CADASIL study: learning more about this condition
This study is building a group of Australians with CADASIL (a genetic condition that affects blood vessels in the brain) to learn more about the disease. As a participant, you will have a medical exam, a blood test, and a short memory test.
Newcastle, New South WalesAges 18 years+ - NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.