Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06127264Recruiting
Testing force in a carbon fiber leg brace cuff
This study tests how well a sensor measures force in the top part of a carbon fiber leg brace. It may help improve brace design for people who need them.
Iowa City, IowaAges 18–90 - NCT06127459Recruiting
Virtual reality to help kids with brain injury improve thinking skills
This trial tests if virtual reality exercises can help children aged 8-12 with mild or moderate traumatic brain injury improve their attention and thinking skills. It is designed for children whose challenges were confirmed by a psychologist and who speak Finnish.
OuluAges 8–12 - NCT06128148RecruitingPhase 1
Study of JYP0322 for ROS1 fusion-positive solid tumors
This trial tests an experimental drug called JYP0322 for people with advanced solid tumors that have a specific genetic change called a ROS1 fusion. The goal is to see if the drug is safe and effective against these tumors.
Guangzhou, GuangdongAges 18 years+ - NCT06128746Recruiting
Brain stimulation for muscle tightness in children with cerebral palsy
This trial tests a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to see if it can reduce muscle tightness (spasticity) in the arm of children with cerebral palsy or hemiplegia caused by a brain injury. It is a randomized controlled trial, meaning some children will receive the active treatment and others a placebo, to find out if it really helps.
Hong Kong, Hong KongAges 7–18 - NCT06128720Recruiting
Hyperbaric oxygen therapy for optic nerve damage
This study tests if breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with optic neuropathy, a condition that damages the nerve connecting the eye to the brain.
Palo Alto, CaliforniaAges 18 years+ - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06129175RecruitingPhase 2/Phase 3
Stem cells for recent moderate to severe stroke
This trial is testing a new treatment using stem cells from donated umbilical cord tissue to help people recover from a recent moderate to severe stroke. It is for patients who cannot receive standard clot-busting treatments.
Cheras, Kuala LumpurAges 18 years+ - NCT06129656Recruiting
Cardiac Amyloidosis Registry at Leipzig Hospital
This study is a registry that collects information from people with cardiac amyloidosis. It helps doctors learn more about the condition and how to better treat it.
Leipzig, SaxonyAges Any age - NCT06129838Recruiting
Inflammation in Alzheimer's disease using a brain scan
This study uses a special PET scan to look for inflammation in the brains of people with Alzheimer's or related dementias. It may help researchers understand how inflammation affects memory and thinking problems.
St Louis, MissouriAges 50 years+ - NCT06130449RecruitingEarly Phase 1
Testosterone and brain function in men with spinal cord injury
This study tests whether testosterone can help brain function in men with spinal cord injury and low testosterone. If you qualify, you would receive testosterone treatment and have your brain activity measured over about a month.
The Bronx, New YorkAges 18–80 - NCT06129890Recruiting
Brain stimulation for nerve pain and depression
This trial tests whether a noninvasive brain stimulation technique (rTMS) can help people with long-term nerve pain who also have depression. It aims to see if this treatment can reduce pain and improve mood.
Saint-EtienneAges 18–85 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT06131385Recruiting
Tracking IV clot-busting treatment for stroke in China
This study is tracking patients in southwestern China who have had an acute ischemic stroke and received a clot-busting medicine through an IV. It aims to learn more about how well this treatment works and how it is used in real-world settings.
LuzhouAges Any age - NCT06132399Recruiting
Virtual reality software for recent stroke recovery
This trial tests whether using virtual reality exercises can help people who recently had a stroke regain movement in their arms or legs. If you had a stroke 7 to 14 days ago and have weakness on one side, this study may help with your recovery.
Almería, AlmeríaAges 18 years+ - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06132685RecruitingPhase 2
Dexamethasone dosing after brain tumor surgery
This trial tests how to best use dexamethasone (a steroid) after brain tumor surgery to help recovery and reduce swelling. It looks at different dosing schedules for patients with common brain tumors.
Atlanta, GeorgiaAges 18 years+ - NCT06132893RecruitingPhase 2/Phase 3
Testing BHV-7000 for hard-to-control focal seizures in adults
This study tests a new medicine called BHV-7000 for adults whose focal seizures (starting in one part of the brain) are not controlled by current treatments. The goal is to see if it can reduce seizures safely.
Phoenix, ArizonaAges 18–75 - NCT06133179Recruiting
Super-resolution brain ultrasound for stroke patients
This trial tests a new 3D ultrasound technique to get clearer images of blood flow in the brain after a stroke, which could help doctors better understand and treat the damage.
Paris, Île-de-France RegionAges 18 years+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06133712Recruiting
Injection treatment for carpal tunnel pain
This trial tests whether a local injection of three medications (dexmedetomidine, ozone, and dexamethasone) can relieve pain and symptoms in people with mild-to-moderate carpal tunnel syndrome. It aims to provide a non-surgical option for those who haven't improved with other treatments.
Tanta, El GharbiaAges 20–60 - NCT06135753Recruiting
Mind-Body Treatment for Fibromyalgia
This study tests a mind-body (psychosomatic) approach for people with fibromyalgia to see if it can help manage symptoms. It is not a medication trial, but a psychological treatment program.
Florence, Italia/FirenzeAges 18 years+ - NCT06136572Recruiting
Study on assertiveness and emotions in Tourette's
This study looks at how people with Tourette's syndrome manage emotions and assertiveness. It may help doctors understand the challenges patients face.
Clermont-Ferrand, FranceAges 18 years+ - NCT06136884RecruitingPhase 1
Study of AO-252 for advanced solid tumors with or without brain metastases
This trial tests an experimental oral pill (AO-252) that targets a protein called TACC3 in advanced solid tumors, including those that have spread to the brain. It is for people whose cancer has a specific genetic change (TP53 mutation) or who have prostate cancer, and who have already tried other treatments.
Detroit, MichiganAges 18 years+ - NCT06137664RecruitingPhase 1/Phase 2
New oral polio vaccine study for adults, children, and newborns
This trial tests new oral polio vaccines in healthy adults, children, and newborns. It aims to see if these vaccines are safe and help protect against polio.
DhakaAges birth–45 years
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.