Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06203093Recruiting
CMT sample collection for stem cell research
This study collects blood, saliva, or skin samples from people with Charcot-Marie-Tooth disease (CMT) and healthy volunteers. The samples are used to create stem cells (iPSCs) and build a biobank to help researchers understand and treat CMT.
New York, New YorkAges 5 years+ - NCT06203626Recruiting
Portable MRI for brain imaging at the bedside
This study is testing a new, portable MRI machine that can be used right at your bedside. It aims to see if it can take clear pictures of the brain for people with strokes, brain conditions, or symptoms of a brain problem.
Bethesda, MarylandAges 3–99 - NCT06203860Recruiting
Heart-focused clinic for diabetes and heart disease
This study is testing whether a special heart-focused clinic can help people with type 2 diabetes who also have heart or blood vessel problems. If you have both diabetes and a heart condition like prior heart attack, stroke, heart failure, or hard-to-control high blood pressure, this program may support your health.
Svendborg, Region SyddanmarkAges 19 years+ - NCT06203873Recruiting
Comparing biodegradable vs. metal heart-hole closures for migraine
This trial compares two types of devices (biodegradable vs. metal) to close a small hole in the heart (PFO) in people who have migraine not controlled by usual treatments. It aims to see which device works better to reduce migraine attacks.
Beijing, Beijing MunicipalityAges 18–65 - NCT06204744Recruiting
Home arm and hand exercises after stroke
This trial tests a home-based exercise program for people who have weakness in one arm or hand after their first stroke. It aims to help improve movement and function without needing to go to a clinic.
Chiayi CityAges 20 years+ - NCT06205043Recruiting
Smart DBS tuning for Parkinson's disease
This study tests a new computer-guided method for fine-tuning Deep Brain Stimulation (DBS) settings in people with Parkinson's disease. The goal is to find the best stimulation settings more efficiently and improve symptom control.
Mumbai, MaharashtraAges Any age - NCT06205147Recruiting
Elastic band exercise for strength and mood in older hospital patients
This study tests whether using elastic bands for resistance exercises can help older adults in the hospital improve their muscle strength and reduce symptoms of depression. If you are 65 or older, staying in the hospital for more than a week, and able to follow simple instructions, this might be a good fit.
Taipei, TaiwanAges 65 years+ - NCT06205160Recruiting
Flexible brain electrodes for epilepsy surgery
This trial is testing new flexible brain electrodes during epilepsy surgery. These electrodes may help doctors map brain activity better than standard rigid ones. If you are having surgery for epilepsy caused by a brain lesion, you might be able to join.
UtrechtAges 18 years+ - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06207136Recruiting
Diet and Gut Bacteria in Parkinson's
This study looks at how diet and the bacteria in your gut (microbiome) affect Parkinson's symptoms. You'll work with a coach and take cooking classes to see if changing what you eat can help you feel better.
Vancouver, British ColumbiaAges 40–80 - NCT06207552RecruitingEarly Phase 1
Gene therapy study for children with Fabry disease
This study tests a new gene therapy for children aged 7 to 17 with Fabry disease. The treatment aims to fix the faulty gene that causes the condition, which may help reduce symptoms and prevent organ damage.
ShanghaiAges 7–18 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06207942Recruiting
Extended follow-up for cardiac arrest survivors and caregivers
This study follows up on survivors of out-of-hospital cardiac arrest who were already in the STEPCARE trial. It also looks at the well-being of their main caregiver (like a family member or close friend) to see how everyone is doing over time.
BrisbaneAges 18 years+ - NCT06208332RecruitingPhase 2
Communication support for kids with severe neurological needs
This study tests a new communication program to help families and doctors talk about what matters most to your child with a severe neurological condition. It is for hospitalized children ages 6 months to 25 years old, who have had their condition for more than 6 months.
Seattle, WashingtonAges 6 months+ - NCT06208514Recruiting
Brief Pain Exposure Therapy for chronic pain conditions
This study tests a type of talk therapy called Brief Pain Exposure Therapy (BPET) for people with certain chronic pain conditions like fibromyalgia, lupus, or chronic low back pain. It aims to help reduce pain by changing how your brain responds to it.
Ann Arbor, MichiganAges 18 years+ - NCT06208709Recruiting
Carpal tunnel treatment for right hand without surgery
This study tests a new way to treat carpal tunnel syndrome in the right hand without surgery. It may help people with mild to moderate symptoms who have not had recent injections or other treatments.
Tucson, ArizonaAges 18 years+ - NCT06208657RecruitingPhase 1/Phase 2
Personalized cancer therapy for kids and teens
This trial tests personalized cancer treatments for children and teens whose cancer has not responded to standard therapy. It uses information from precision medicine studies to match the right drug to each child's tumor.
Newcastle, New South WalesAges birth–21 years - NCT06208813Recruiting
Creatine for Concussion Recovery in Young Adults
This study tests whether taking creatine (a natural muscle supplement) can help young adults recover faster after a concussion. The trial starts very soon after injury, within the first 3 days.
San Diego, CaliforniaAges 18–35 - NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT06211257Recruiting
Digital info vs standard leaflets for advanced sarcoma
This trial is testing a digital tool (like videos or online info) to help people with advanced sarcoma understand their treatment better. It compares the digital tool to standard printed leaflets to see which improves understanding and wellbeing.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT06210633Recruiting
Clot removal trial for very large strokes
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
Xiangtan, HunanAges 18 years+ - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06211491Recruiting
Bladder filling speed and autonomic dysreflexia in spinal cord injury
This trial compares how fast the bladder is filled during a urodynamic test and how that affects autonomic dysreflexia (a sudden rise in blood pressure) in people with chronic spinal cord injury. It aims to find safer testing methods.
Yangsan, Gyeongsangnam-doAges Any age - NCT06211712Recruiting
Drug plus clot removal for large vessel stroke
This study tests whether adding a drug called human urinary kallidinogenase to standard clot-removal therapy helps people recover better after a large-vessel stroke. If you qualify, you would receive the drug or a placebo by IV along with the procedure, and doctors will monitor your recovery.
ShanghaiAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.