Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06591351RecruitingPhase 3
Aspirin plus cilostazol or clopidogrel for minor stroke or TIA
This trial tests whether adding cilostazol or clopidogrel to aspirin is safe and effective for people who recently had a mild stroke or a transient ischemic attack (TIA) caused by a large artery blockage. It aims to prevent another stroke during the first 90 days.
Kafr ash ShaykhAges 18–75 - NCT06591390RecruitingPhase 3
Aspirin plus another drug for minor stroke or TIA
This trial tests whether taking aspirin along with either ticagrelor or cilostazol helps prevent another stroke in people who have had a mild stroke or transient ischemic attack (mini-stroke). You must start treatment within 24 hours of your first symptoms.
Kafr ash ShaykhAges 18–75 - NCT06591377RecruitingPhase 3
Aspirin plus a second drug for minor stroke or TIA
This trial tests whether adding ticagrelor or cilostazol to aspirin is better than aspirin alone for preventing another stroke. It is for patients who recently had a minor stroke or a transient ischemic attack (TIA) caused by a blockage in a large artery.
CairoAges 18–75 - NCT06591429Recruiting
A study on hidden inflammation in multiple sclerosis
This study uses brain scans to look for hidden inflammation in people with multiple sclerosis who have not yet started a strong treatment. It aims to understand how this inflammation affects the disease and to help guide future therapies.
St Louis, MissouriAges 18 years+ - NCT06591793RecruitingPhase 1/Phase 2
Gene therapy for Usher syndrome type 1B vision loss
This trial tests an experimental gene therapy given as an injection under the retina. It aims to slow or stop vision loss in people with Usher syndrome type 1B, a rare genetic condition that causes both hearing and vision problems.
NaplesAges 18–50 - NCT06591975Recruiting
Upper extremity function and balance in Parkinson's disease
This study looks at how arm and hand function relates to balance and mobility in people with Parkinson's disease. Understanding this link may lead to better therapy approaches.
SivasAges 18–80 - NCT06592352RecruitingPhase 2
Modafinil for thinking problems in MS
This study tests whether the medication modafinil can improve thinking and memory problems in people with MS. If you have MS and notice cognitive changes like forgetfulness or trouble focusing, you may be eligible.
BragaAges 18–64 - NCT06592703RecruitingPhase 1
Stem cells for primary progressive MS
This study tests whether stem cells from donated fat tissue can slow down primary progressive multiple sclerosis. You would receive a single injection of the cells into your spinal fluid and be followed for up to 2 years.
CréteilAges 18–55 - NCT06593184Recruiting
Magnetic stimulation for mobility after stroke
This trial tests a non-invasive treatment called trans-spinal magnetic stimulation to help improve walking and movement in people who have had a stroke. It is for those with trouble walking and are at least 6 months past their stroke.
João Pessoa, ParaíbaAges 18–75 - NCT06593951Recruiting
EPM1 natural history study
This study will follow people with EPM1 over time to better understand the disease. It is a registry, meaning you will share information through video calls and questionnaires, with no experimental treatments involved.
Boston, MassachusettsAges Any age - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT06595511Recruiting
Combined sound, light, and games for Alzheimer's
This study tests a new approach combining special audio-visual stimulation (at 40 Hz) with cognitive games to see if it can help people with Alzheimer's disease. It also includes a group of healthy older adults for comparison.
Istanbul, BeykozAges 60–86 - NCT06596187Recruiting
Study of muscle tightness in spinal cord injury and Parkinson's
This study looks at muscle tightness (hypertonia) in people with spinal cord injury, Parkinson's disease, and healthy volunteers. It aims to better understand and measure different types of stiffness to improve treatments.
TaoyuanAges 20 years+ - NCT06596174Recruiting
Spinal stimulation and ankle training for spinal cord injury
This trial tests if adding a non-invasive spinal stimulation technique to ankle movement training can improve recovery in people with chronic spinal cord injury. It might be relevant if you have had a spinal cord injury for more than a year and are not on certain medications.
TaoyuanAges 20 years+ - NCT06596369RecruitingPhase 2/Phase 3
Spinal cord stimulation for arm function after injury or stroke
This trial tests whether a mild electrical stimulation applied to the skin over your spine can improve arm and hand function after a spinal cord injury or stroke. It is for people with some preserved movement in their upper body.
Edmonton, AlbertaAges 18–75 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06596551Recruiting
Coaching for well-being after first stroke
This study explores a personalized coaching program to help you and your main caregiver improve your overall well-being after your first stroke. You will work with a coach to set goals for your recovery and learn mind-body skills that can boost your health and happiness.
SingaporeAges 21 years+ - NCT06596733Recruiting
Testing a new eye ointment for dry eyes (Vit-A-Vision)
This trial tests a medical device eye ointment called Vit-A-Vision for people with dry eye disease. It aims to see if the ointment can improve symptoms and tear film stability over about a month.
CologneAges 18 years+ - NCT06597383Recruiting
Switching to pasireotide for acromegaly not well controlled
This trial tests if switching from a standard somatostatin analog to pasireotide can better control acromegaly in patients whose growth hormone and IGF-1 levels remain high. It aims to offer a more effective treatment option for those not responding well enough to initial therapy.
MilanAges 18 years+ - NCT06597981Recruiting
Sport stacking program for mild dementia and caregivers
This trial tests a fun sport stacking activity for people with mild dementia and their family caregivers. It aims to improve well-being and connection through a simple, home-based program.
ChongqingAges 18 years+ - NCT06598150Recruiting
Brain mapping study for chronic arm weakness after stroke
This study uses MRI scans to understand how the brain controls arm movement in people who have had a stroke. It aims to help develop better rehabilitation therapies for chronic arm weakness.
Chicago, IllinoisAges 18 years+ - NCT06598189Recruiting
Ear-seizure detection study for epilepsy monitoring
This study tests a wearable ear device that may help detect seizures during your stay in the Epilepsy Monitoring Unit. It aims to see if the device can work alongside standard monitoring to improve seizure detection.
Worcester, MassachusettsAges 18 years+ - NCT06598202RecruitingPhase 1/Phase 2
Nasal Drop Therapy for ALS
This trial tests a nasal drop made from tiny cell particles (extracellular vesicles) for ALS. The goal is to see if it's safe and if it can slow down the disease. It may be an option if your ALS is in the early to moderate stage.
Beijing, Beijing MunicipalityAges 18–80 - NCT06598449RecruitingPhase 4
Safety of fenfluramine in children under 2 with Dravet syndrome
This trial tests the safety of a medicine called fenfluramine for children under 2 years old with Dravet syndrome. It aims to see if fenfluramine can help control seizures in very young children.
Aurora, ColoradoAges 1–2
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.